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Bioinformatics   Research Article

Development of polymorphic microsatellite markers for Dioscorea zingiberensis and cross-amplification in other Dioscorea species

Authors: Q.-Q. Yan, X.-Q. Sun, J.-L. Guo, Y.-Y. Hang and M.-M. Li

Dioscorea zingiberensis C.H. Wright (Dioscoreaceae) is an endemic species in central and southwestern China. In order to study the genetic diversity and population structure of this species, 19 novel polymorphic microsatellite loci were developed using a dual-suppression PCR technique. The number of alleles per locus ranged from 3 to 21, with an average o.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.10
DOI:
10.4238/2013.September.19.10
Human Genetics   Research Article

Genetic structure of Aedes aegypti populations determined using pairwise comparisons

Authors: T. de F. Patarro, M.M. Guirado, L.M. Ravazzi and H.E.M. de C. Bicudo

The biological characteristics of Aedes aegypti (Diptera, Culicidae), which is a vector of dengue and yellow fever, make this organism a good model for studying population structure and the events that may influence it under the effect of human activity. We assessed the genetic variability of five A. aegypti populations using RAPD-PCR technique and six pr.. Read More»

Genet. Mol. Res. 12(3):
2013.September.19.9
DOI:
10.4238/2013.September.19.9
Animal Genetics   Research Article

Neuroprotective effect of ketamine on acute spinal cord injury in rats

Authors: S.H. Tang, J.G. Yu, J.J. Li and J.Y. Sun

The aim of this study was to investigate the neuroprotective effects of ketamine during acute spinal cord injury in rats. Sprague Dawley (SD) rats (N = 70) were randomly divided into three groups: sham-operated (N = 10), control (N = 30), and treatment (N = 30) groups. The moderate spinal cord injury model was established. After injury, the sham-operated .. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.4
DOI:
http://dx.doi.org/10.4238/2015.April.17.4
Animal Genetics   Research Article

Genetic analysis of QTL for eye cross and eye diameter in common carp (Cyprinus carpio L.) using microsatellites and SNPs

Authors: S.B. Jin, X.F. Zhang, J.G. Lu, H.T. Fu, Z.Y. Jia and X.W. Sun

A group of 107 F1 hybrid common carp was used to construct a linkage map using JoinMap 4.0. A total of 4877 microsatellite and single nucleotide polymorphism (SNP) markers isolated from a genomic library (978 microsatellite and 3899 SNP markers) were assigned to construct the genetic map, which comprised 50 linkage groups. The total length of the linkage .. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.5
DOI:
http://dx.doi.org/10.4238/2015.April.17.5
Animal Genetics   Research Article

Health and production traits in bovine are associated with single nucleotide polymorphisms in the NOD2 gene

Authors: W. Wang, L. Cheng, J. Yi, J. Gan, H. Tang, M.Z. Fu, H. Wang and S.J. Lai

The NOD2 gene plays a fundamental role in initiating the inflammatory and subsequent immune response. NOD2 was previously identified as a susceptibility locus for inflammatory bowel diseases in humans. In this study, we detected 2 mutations in exon 12 (A→T, G→A) among 5 cattle breeds (N = 315) and analyzed their associations with production trai.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.6
DOI:
http://dx.doi.org/10.4238/2015.April.17.6
Animal Genetics   Research Article

Population genetic structure and historical demography of the ground beetle Chlaenius costiger in the Tsinling-Dabashan Mountains of central China

Authors: L.-N. Su, X.-C. Li, H.-Z. Meng, X.-Y. Gao, H. Yin and K. Li

Population genetic structure and demographic history of the ground beetle Chlaenius costiger (Coleoptera: Carabidae) in the Tsinling-Dabashan Mountains of central China were estimated using mitochondrial DNA sequences (Cox1-tRNALeu-Cox2) of 144 individuals from 16 local populations. The high haplotype diversity was accompanied by low nucleotide diversity... Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.7
DOI:
http://dx.doi.org/10.4238/2015.April.17.7
Human Genetics   Research Article

Meta-analytical association between angiotensin-converting enzyme gene polymorphisms and sarcoidosis risk

Authors: R. Zhu, L.Q. Bi, H. Kong, S.L. Tilley, H. Wang and W.P. Xie

Previous reports identified an association between sarcoidosis and an insertion/deletion (I/D) polymorphism in angiotensin-converting enzyme. Our meta-analysis of articles published between March 1996 and June 2013 identified studies in the PubMed, EMBASE, and the China National Knowledge Infrastructure databases. We examined whether angiotensin-convertin.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.8
DOI:
http://dx.doi.org/10.4238/2015.April.17.8
Human Genetics   Research Article

Microsatellite markers reveal genetic divergence among wild and cultured populations of Chinese sucker Myxocyprinus asiaticus

Authors: W.W. Cheng, D.Q. Wang, C.Y. Wang, H. Du and Q.W. Wei

Studies of genetic diversity and genetic population structure are critical for the conservation and management of endangered species. The Chinese sucker Myxocyprinus asiaticus is a vulnerable monotypic species in China, which is at a risk of decline owing to fluctuations in effective population size and other demographic and e.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027581
DOI:
10.4238/gmr.15027581
Human Genetics   Research Article

Description of the pre-reductional sex chromosome during male meiosis of Pachylis laticornis (Heteroptera: Coreidae)

Authors: C.A. Banho, K.C.C. Alevi, L.L.V. Pereira, T.S. Souza-Firmino and M.M. Itoyama

In Heteroptera, the division of sex chromosomes is well defined as post-reductional for most of species, i.e., the first meiotic division is equational and the second is reductional. However, in some species pre-reductional division has been observed, whereby the first meiotic division is reductional and the second is equation.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027592
DOI:
10.4238/gmr.15027592
Medical Genetics   Research Article

Xuemaitong granules attenuate carotid atherosclerosis by decreasing the expression of CD14+CD16+ monocytes, IL-6, TNF-�±, and hsCRP

Authors: Q. Zhang, G. Qian and Z. Ding

Carotid atherosclerosis (CAS) has been extensively studied because its position can be easily observed. Our objective was to investigate the effects of Xuemaitong granules on the generation and activation of CD14+CD16+ monocytes on the inflammatory reaction in CAS patients. In this study, 22 male apolipoprotein E (apoE)-defici.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.19
DOI:
10.4238/2014.September.12.19