Toll-like receptor-4-dependence of the lipopolysaccharide-mediated inhibition of osteoblast differentiation
Authors: Y.H. Liu, D. Huang, Z.J. Li, X.H. Li, X. Wang, H.P. Yang, S.P. Tian, Y. Mao, M.F. Liu, Y.F. Wang, Y. Wu and X.F. Han
Bone fractures or bones subjected to open conduction and internal fixation are easily infected by bacteria; bacterial lipopolysaccharide (LPS) has been recognized as an important pathogenic factor affecting bone fracture healing. Therefore, the effect of LPS on bone metabolism is relevant for bone healing. In this study, we in.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027191
- DOI:
- 10.4238/gmr.15027191
Investigating the recheck rules for urine analysis in children
Authors: Y.M. He, S.W. Yao, Y.J. Huang, B.S. Liang and H.Y. Liu
The aim of this study was to establish recheck rules of urinalysis in children by investigating the concordance rate of the results obtained using the LabUMat urine dry chemistry analyzer (referred to as dry chemistry) and the UriSed tangible composition analyzer with that of the microscopic examination. First, 1040 urine samp.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027349
- DOI:
- 10.4238/gmr.15027349
Role of the IL-11/STAT3 signaling pathway in human chronic atrophic gastritis and gastric cancer
Authors: D.Q. Wang, X.P. Ding, S. Yin and Y.D. Mao
The expression of interleukin-11 (IL-11) and its products STAT3 and phospho-STAT3 (p-STAT3) in patients with chronic superficial gastritis (CSG), chronic atrophic gastritis (CAG), and gastric cancer (GC) may provide insight into the diagnostic role of the IL-11/STAT3 signaling pathway in GC. Gastric mucosa specimens and serum .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027358
- DOI:
- 10.4238/gmr.15027358
Evaluation of the taxonomic status of water dropwort (Oenanthe, Apiaceae) accessions from East Asia based on nuclear rDNA internal transcribed spacer sequences
Authors: S. Fu, L.N. Li, Z.C. Long, W.D. Ke, A.H. Ye, Y.H. Guo and J.M. Chen
Oenanthe L. is a taxonomically complex genus, several species of which have long been used as vegetables and traditional medicines in East Asia. In order to clarify the taxonomic status of Oenanthe accessions and provide baseline data for the sustainable use of its genetic resources, we examined sequence variations in the inte.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027363
- DOI:
- 10.4238/gmr.15027363
Relationship between TLR4 and MCP2 expression levels and habitual abortion
Authors: X.P. Li, L.N. Song, L.P. Tian and Y.S. Zhang
Habitual abortion is associated with the altered expression of multiple genes. This study was carried out to investigate the relationship between expression of Toll-like receptor 4 (TLR4) and monocyte chemotactic protein 2 (MCP2 or CCL8) and habitual abortion. This was done by detecting and comparing their relative expression .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027378
- DOI:
- 10.4238/gmr.15027378
Transcriptome expression profiling of fur color formation in domestic rabbits using Solexa sequencing
Authors: L.Z. Qin, W.Z. Wang, L.J. Shi, X.Y. Wan, X.R. Yan, Q.Q. Weng and X.S. Wu
Fur color is an important, genetically determined characteristic of domestic rabbits, and rabbit furs are of great economic value. To investigate the molecular genetics associated with fur color determination in domestic rabbits, we used Solexa-sequencing technology to probe gene expression in dorsal skin tissues sampled from .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027413
- DOI:
- 10.4238/gmr.15027413
Systematic tracking of altered modules identifies disrupted pathways in teratozoospermia
Authors: Z.Q. Huang, G.X. Wang, X.L. Jiang, E.P. Tian, W.L. Yao and T. Zeng
The objective of this study was to identify disrupted pathways in teratozoospermia by systematically tracking dysregulated modules in reweighted protein-protein interaction (PPI) networks. We inferred and reweighted the PPI networks of normal and teratozoospermia groups based on Spearman correlation coefficients. Modules in th.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027514
- DOI:
- 10.4238/gmr.15027514
Mammaglobin and maspin transcripts in blood may reflect disease progression and the effect of therapy in breast cancer
Authors: O. Bitisik, P. Saip, S. Saglam, D. Derin and N. Dalay
Detection of residual tumor cells in the circulation can provide prognostic as well as therapeutic information and help in identifying patients at high risk for developing metastases. Maspin and mammaglobin are two molecules that are specifically associated with breast cancer. We looked for mammaglobin and maspin transcripts i.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr649
- DOI:
- 10.4238/vol9-1gmr649
Association of lipase lipoprotein polymorphisms with high-density lipoprotein and triglycerides in elderly men
Authors: L.M.Q. Ara�ºjo, M.S. Cendoroglo, C.O. Gigek, E.S. Chen and M. de A.C. Smith
Lipoprotein lipase is essential for triglyceride hydrolysis. The polymorphisms S447X in exon 9 and HindIII in intron 8 have been associated with lower triglyceride levels and lower cardiovascular risk in adult men. We examined the association of these lipoprotein lipase polymorphisms with high-density lipoprotein (HDL) and tri.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr689
- DOI:
- 10.4238/vol9-1gmr689
Analysis of genetic diversity of Brassica rapa var. chinensis using ISSR markers and development of SCAR marker specific for Fragrant Bok Choy, a product of geographic indication
Authors: X.L. Shen, Y.M. Zhang, J.Y. Xue, M.M. Li, Y.B. Lin, X.Q. Sun and Y.Y. Hang
Non-heading Chinese cabbage [Brassica rapa var. chinensis (Linnaeus) Kitamura] is a popular vegetable and is also used as a medicinal plant in traditional Chinese medicine. Fragrant Bok Choy is a unique accession of non-heading Chinese cabbage and a product of geographic indication certified by the Ministry of Agriculture of C.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027557
- DOI:
- 10.4238/gmr.15027557