Marker-assisted selection in breeding silkworm strains with high silk production and resistance to the densonucleosis virus
Authors: C.X. Hou1, P.J. Sun1, X.J. Guo1,2, Y.P. Huang3 and M.W. Li1,2
In the silkworm (Bombyx mori), resistance to the Zhenjiang (China) strain of the densonucleosis virus (DNV-Z) is controlled by the recessive gene nsd-Z (non-susceptible to DNV-Z), which is linked to 7 simple-sequence repeat markers. Marker-assisted evaluation and selection of DNV-Z-resistant silkworms were used for predicting DNV-resistance in backcrossed.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.7.3
- DOI:
- 10.4238/2013.October.7.3
Low-frequency ultrasound induces apoptosis of rat aortic smooth muscle cells (A7r5) via the intrinsic apoptotic pathway
Authors: B. Zhang, H.S. Zhou, Q. Cheng, L. Lei and B. Hu
Ultrasound, a non-invasive therapy method, is a potential tool for medical applications, but its biological effects on vascular smooth muscle cells (VSMCs) have not been characterized. The aim of this study was to explore the effect and possible apoptotic mechanism of VSMCs that were induced by low-frequency ultrasound (LFU). .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.10
- DOI:
- 10.4238/2014.April.17.10
A novel SCAR marker for detecting Psathyrostachys huashanica Keng chromatin introduced in wheat
Authors: W.L. Du, J. Wang, L.M. Wang, Y.H. Pang, J. Wu, J.X. Zhao, Q.H. Yang and X.H. Chen
In this study, we cloned and sequenced a 938-base pair polymorphic band, pHs27, in the tightly linked random amplified polymorphic DNA marker OPU10 and converted it into a sequence-characterized amplified region (SCAR) marker referred to as RHS141, which was specific for the Ns genome of Psathyrostachys huashanica. A GenBank basic local alignment search t.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.16
- DOI:
- 10.4238/2013.October.18.16
Interleukin-7 receptor gene polymorphism at +1237 locus and its effect on susceptibility to opportunistic infections among HIV and AIDS patients in Limpopo Province, South Africa
Authors: A. Samie, G.T. Moloro and T.C. Nangammbi
Over the past decade, an increasing number of studies have demonstrated correlations between host genetics and susceptibility to diseases. However, few studies have investigated the effects of host genetics on the occurrence of opportunistic infections among human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients. In the .. Read More»
- Genet. Mol. Res. 13(4):
Association of beta 2 adrenoceptor gene polymorphisms in Malaysian hypertensive subjects
Authors: M. Komara, R. Vasudevan, P. Ismail, S.A. Bakar, S.R. Pishva and F. Heidari
The sympathetic nervous system plays a major role in blood pressure regulation. Beta 2 (β2) adrenoceptor gene polymorphisms have been associated with hypertension in different populations with conflicting results. We examined the association of three common polymorphisms, Arg16Gly, Gln27Glu, and Thr164Ile, of the β2 .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.2
- DOI:
- 10.4238/2014.April.16.2
Expression profiling analysis of hypoxic pulmonary disease
Authors: L. Zhou, L.M. Wang, H.M. Song, Y.Q. Shen, W.J. Xu, J.H. Xu, Y. Liu, W.W. Yan and J.F. Jiang
Exposure of humans to low levels of environmental oxygen results in alveolar hypoxia and normally causes chronic pulmonary hypertension and morphological alterations of precapillary pulmonary vessels. In this study, the microarray dataset GSE11341 was used to identify potential differentially expressed genes related with human lung microvascular endotheli.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.7.2
- DOI:
- 10.4238/2013.October.7.2
Association study of polymorphisms between the Radixin gene and rheumatoid arthritis in a Korean population
Authors: H.-K. Kim, J.-S. Joo, H.-Y Lee, J.-T. Kwon, D.-R. Sohn, S.-J. Hong and H.-J. Kim
Radixin (RDX) is part of the ezrin-radixin-moesin (ERM) protein family. It functions as a membrane-cytoskeletal linker in actin-rich cell surface structures and is thought to be essential for cortical cytoskeleton organization, cell motility, adhesion, and proliferation. An increase in phosphorylated ERM in fibroblast-like syn.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.14
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.14
Differential expression and effect of the porcine ANGPTL4 gene on intramuscular fat
Authors: Z.Q. Ren, W.J. Wu, W.H. Liu, R. Zheng, J.L. Li, B. Zuo, D.Q. Xu, F.E. Li, M.G. Lei, D.B. Ni and Y.Z. Xiong
In a previous study, we investigated differences in gene expression in backfat between Meishan and Large White pigs and their F1 hybrids, Large White x Meishan, and Meishan x Large White pigs. One potential differentially expressed sequence tag from the mRNA differential display was a homolog of the human angiopoietin-like 4 (.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.3
- DOI:
- 10.4238/2014.April.16.3
Expression of ERCC1 and BRCA1 predict the clinical outcome of non-small cell lung cancer in patients receiving platinum-based chemotherapy
Authors: T.B. Wang, N.L. Zhang, S.H. Wang, H.Y. Li, S.W. Chen and Y.G. Zheng
We examined mRNA expression levels of ERCC1, BRCA1, RRM1, and human β-tubulin-III (TUBB3) in non-small-cell lung carcinoma (NSCLC) patients and investigated the association between expression of these genes and the clinical outcome of NSCLC treatment. A total of 366 patients who underwent surgery for NSCLC were included i.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.15
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.15
A tiered barcode authentication tool to differentiate medicinal Cassia species in India
Authors: N. Purushothaman, S.G. Newmaster, S. Ragupathy, N. Stalin, D. Suresh, D.R. Arunraj, G. Gnanasekaran, S.L. Vassou, D. Narasimhan and M. Parani
DNA barcoding is a desirable tool for medicinal product authentication. DNA barcoding is a method for species identification using short DNA sequences that are conserved within species, but variable between species. Unlike animals, there is no single universal DNA barcode locus for plants. Coding markers, matK and rbcL, and no.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.16.4
- DOI:
- 10.4238/2014.April.16.4