Using artificial neural networks to select upright cowpea (Vigna unguiculata) genotypes with high productivity and phenotypic stability
Authors: L.M.A. Barroso, P.E. Teodoro, M. Nascimento, F.E. Torres, A.C.C. Nascimento, C.F. Azevedo and F.R.F. Teixeira
Cowpea (Vigna unguiculata) is grown in three Brazilian regions: the Midwest, North, and Northeast, and is consumed by people on low incomes. It is important to investigate the genotype x environment (GE) interaction to provide accurate recommendations for farmers. The aim of this study was to identify cowpea genotypes with hig.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049049
- DOI:
- 10.4238/gmr15049049
Upregulation of miR-3658 in bladder cancer and tumor progression
Authors: Y.J. Chen, H.F. Wang, M. Liang, R.C. Zou, Z.R. Tang and J.S. Wang
Despite increasing advances in surgical techniques and adjuvant chemotherapies, bladder cancer remains the ninth leading cause of male malignancy-associated deaths worldwide. Several microRNAs (miRNAs) have been identified to be closely associated with the progression and prognosis of, and response to treatments in various hum.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049048
- DOI:
- 10.4238/gmr15049048
Cloning and expression of the 1-aminocyclopropane-1-carboxylic oxidase gene from Agrostis stolonifera
Authors: G.Z. Xiao, L.J. Li, K. Teng, Y.H. Chao and L.B. Han
A gene encoding 1-aminocyclopropane-1-carboxylic oxidase (ACO), which catalyzes the terminal step in ethylene biosynthesis, was isolated from Agrostis stolonifera. The AsACO gene is composed of 975 bp, encoding 324 amino acids. Three exons interspersed by two introns form AsACO gDNA. A BLAST search of the nucleotide sequence r.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049034
- DOI:
- 10.4238/gmr15049034
Combined effect of traditional Chinese and Western medicine on inflammatory factors in patients with diabetes-induced xerophthalmia
Authors: S.Q. Wu, Q. Dai, J.L. Xu, W.Y. Sheng, Q.B. Xu and L.Y. Zhong
Diabetes-induced xerophthalmia is a general metabolic disorder with high incidence and increased treatment difficulty. Our study aimed to explore the combined effect of traditional Chinese and Western medicines on diabetes-associated xerophthalmia. We recruited 60 diabetic xerophthalmia patients, and randomly assigned them to .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049030
- DOI:
- 10.4238/gmr15049030
Molecular cloning and expression analysis of a matrix Gla protein gene in the spinyhead croaker, Collichthys lucidus
Authors: W. Song, M.D. Zhao, K.J. Jiang, F.Y. Zhang, M. Zhao, Y.Y. Meng and L.B. Ma
The matrix Gla (gamma-carboxyglutamic acid-rich) protein (MGP), a vitamin K-dependent and Gla-containing protein, is a calcification inhibitor that mainly functions in tissue calcification and mineralization. In this study, we obtained the complete cDNA sequence of MGP from the spinyhead croaker (Collichthys lucidus), which we.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049028
- DOI:
- 10.4238/gmr15049028
Novel visual system homeobox 1 gene mutations in Turkish patients with keratoconus
Authors: H. Bardak, M. Gunay, E. Yildiz, Y. Bardak, B. Gunay, H. Ozbas and O. Bagci
The aim of this study was to screen the visual system homeobox 1 (VSX1) gene in Turkish patients with keratoconus (KC). The patient group consisted of 44 patients who had undergone corneal transplant surgery before the age of 30, for advanced and rapidly progressive KC. The control group comprised 250 healthy individuals. We d.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049024
- DOI:
- 10.4238/gmr15049024
Liguisticum wallichii inhibits renal carcinoma progression by downregulating UBE3A and through suppression of NF-�ºB signaling
Authors: J.S. Wu, P.M. Zhang, L.J. Sun and X.Z. Liu
Renal carcinoma accounts for a fifth of the morbidity among malignant tumors in China. Ubiquitin-protein ligase E3A (UBE3A) plays an important role in the occurrence and development of gene mutation-induced diseases. This study was designed to investigate the mechanism of Liguistium wallichii in treating renal carcinoma. Hemat.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049023
- DOI:
- 10.4238/gmr15049023
Cell proliferation and apoptosis in the fetal and neonatal ovary of guinea pigs
Authors: S.Y. Sun, W. Zhang, X. Han, R.H. Huang and F.X. Shi
The guinea pig is an excellent animal model for studying reproductive biology of adult humans and most domestic animals. Yet, whether this animal might serve as a good model for embryonic stage investigations and determinations of signals affecting or directing ovary development remains unknown. These questions were addressed .. Read More»
- Genet. Mol. Res. 13(1):
Effects of Shenkangling intervention on the MAPK pathway in rats with doxorubicin-induced nephropathy
Authors: S. Ai, Y.Y. Lin, J. Zheng, C.X. Qiu, Y.J. Liu and X. Lin
Shenkangling plays a role of Yishenhuoxue effect for the treatment of children with nephrotic syndrome. The aim of this study was to investigate the effects of Shenkangling intervention on the mitogen-activated protein kinase (MAPK) pathway in rats with Adriamycin-induced nephropathy (AN) and its underlying mechanism of action. Nephrosis was induced in he.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038131
- DOI:
- 10.4238/gmr.15038131
Mixed models for selection of Jatropha progenies with high adaptability and yield stability in Brazilian regions
Authors: P.E. Teodoro, L.L. Bhering, R.D. Costa, R.B. Rocha and B.G. Laviola
The aim of this study was to estimate genetic parameters via mixed models and simultaneously to select Jatropha progenies grown in three regions of Brazil that meet high adaptability and stability. From a previous phenotypic selection, three progeny tests were installed in 2008 in the municipalities of Planaltina-DF (Midwest), Nova Porteirinha-MG (Southea.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038824
- DOI:
- 10.4238/gmr.15038824