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Plant Genetics   Research Article

Molecular identity of ramie germplasms using simple sequence repeat markers

Authors: M.B. Luan, B.F. Chen, Z.Z. Zou, J.J. Zhu, X.F. Wang, Y. Xu,Z.M. Sun and J.H. Chen

DNA identity is highly effective and efficient for distinguishing crop varieties regardless of their phenotypic similarities. To establish DNA identity in ramie, 21 simple sequence repeat primers were amplified in 108 accessions of domestic and exotic ramie germplasms. Sixty polymorphic bands were obtained, with an average of 2.9 bands per locus and 2-8 b.. Read More»

Genet. Mol. Res. 14(1):
2015.March.27.15
DOI:
10.4238/2015.March.27.15
Human Genetics   Research Article

GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

Authors: A.L. Oliveira, F.F.O. Rodrigues, R.E. Santos, T. Aoki, M.N. Rocha, C.A. Longui and M.B. Melo

The glutathione S-transferase (GST) family consists of phase II detoxification enzymes that catalyze the conjugation of toxic substances, such as chemotherapeutic agents, to glutathione. We examined whether GSTT1/GSTT1“null”, GSTM1/GSTM1“null” and GSTP1Ile105Ile/GSTP1Ile105Val polymorphisms are associat.. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr726
DOI:
10.4238/vol9-2gmr726
Animal Genetics   Research Article

Divergence and polymorphism analysis of IGF1Ra and IGF1Rb from orange-spotted grouper, Epinephelus coioides (Hamilton)

Authors: L. Guo, S. Yang, M.M. Li, Z.N. Meng and H.R. Lin

Orange-spotted grouper (Epinephelus coioides) is one of the most important marine fish and has a high market value. The insulin-like growth factor type 1 receptor (IGF1R) is a component of the insulin-like growth factor signaling system, and demonstrates important roles during growth. Based on information from livestock, we us.. Read More»

Genet. Mol. Res. 15(4):
gmr15048768
DOI:
10.4238/gmr15048768
Animal Genetics   Research Article

Survival of the thriftiest: restricted nurture reveals the thrifty nature of a growth gene in Bos indicus

Authors: S.U. Dani, M.A.C. Dani, I.L. Freire, S.P. Gouvea, F.B. Knackfuss, F.P. Lima, M.E.Z. Mercadante, E. Monteiro, S.M.G. Paggiaro, A.G. Razook and H.C. Yehia

Growth hormone (GH) is a part of the somatotropic axis that controls metabolism, growth, development and aging in a wide range of animals. Mutations that reduce GH signaling have been associated with extended life spans and increased longevity in ways similar to what is observed in dietary restriction (DR) models. However, the.. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr844
DOI:
10.4238/vol9-2gmr844
Human Genetics   Research Article

Correlation of plasma soluble cluster of differentiation 40 ligand, alpha fetoprotein A, and pregnancy-associated plasma protein A with carotid plaque in patients with ischemic stroke

Authors: Y.J. Wang, Z.Q. Gong, X.M. Bi and Y.L Li

This study investigated the correlation of plama levels of inflammatory biomarkers [soluble cluster of differentiation 40 ligand (sCD40L), alpha fetoprotein A (fetuin-A), and pregnancy-associated protein A (PAPP-A)] with carotid plaque in patients with acute ischemic stroke. After undergoing color Doppler ultrasonography of the bilateral carotid arteries,.. Read More»

Genet. Mol. Res. 14(3):
2015.July.17.18
DOI:
10.4238/2015.July.17.18
Human Genetics   Research Article

Correlation between neuronal antibodies and limbic encephalitis in Chinese Han subjects

Authors: Q.M. Chen, H.D. Qu, W.D. Qian, L. Shen, L. Xu, Y.H. Chen,D.Q. Sang, L.N. Zhang, L. Yin, L. Li and H. Wang

A variety of anti-neuronal cell membrane antibodies such as voltage-gated potassium channel antibody, N-methyl-D-aspartate-2B-antibody, and glutamic acid decarboxylase antibody, are correlated with limbic encephalitis (LE). In this study on patients with LE, the clinical manifestations, psychology Wechsler Adult Intelligence Scale, cerebrospinal fluid, el.. Read More»

Genet. Mol. Res. 14(1):
2015.March.27.16
DOI:
10.4238/2015.March.27.16
Animal Genetics   Research Article

TcZFP8, a novel member of the Trypanosoma cruzi CCHC zinc finger protein family with nuclear localization

Authors: A.O. Ericsson, L.O. Faria, W.B. Cruz, C. Martins de S�¡ and B.D. Lima

In a 17-kb genomic fragment of Trypanosoma cruzi chromosome XX, we identified three tandemly linked genes coding for CX2CX4HX4C zinc finger proteins. We also showed that similar genes are present in T. brucei and Leishmania major, sharing three monophyletic groups among these trypanosomatids. In T. cruzi, TcZFP8 corresponds to.. Read More»

Genet. Mol. Res. 5(3):
Animal Genetics   Research Article

Detection of genetic polymorphism among and within Echinococcus granulosus strains by heteroduplex analysis of a microsatellite from the U1 snRNA genes

Authors: P.A. Roratto, M.L. Bartholomei-Santos, A.M. Gutierrez, L. Kamenetzky, M.C. Rosenzvit and A. Zaha

Polymerase chain reaction of a pentanucleotide microsatellite in the U1 snRNA gene complex generated a multiple band pattern due to the priming of paralogous sequences. Denaturation and slow renaturation of polymerase chain reaction products allow the formation of heteroduplex DNA that can be detected by its differential mobil.. Read More»

Genet. Mol. Res. 5(3):
Plant Genetics   Research Article

The synthesis of a new cassava-derived species, Manihot vieiri Nassar*

Authors: N.M.A. Nassar

A new species was synthesized artificially by chromosome doubling in a hybrid. The ensuing polyploid type exhibits an apomictic nature and maintains its morphological characteristics in the progeny. It showed a frequency of multiembryonic sacs of 29% in the ovules examined, whereas sacs were absent in the diploid type... Read More»

Genet. Mol. Res. 5(3):
Plant Genetics   Research Article

Drought tolerant stem anatomy characteristics in Manihot esculenta (Euphorbiaceae) and a wild relative

Authors: N.M.A. Nassar, L.F.A. Abreu, D.A.P. Teodoro and D. Graciano-Ribeiro

The stem structure of two cassava cultivars, UnB 99 and UnB 110, known for being adapted to humid conditions and tolerant to drought, respectively, and of a wild species, Manihot glaziovii, was examined anatomically. Free-hand sections of secondary stems were made, clarified with 50% sodium hypochlorite solution, stained with .. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr800
DOI:
10.4238/vol9-2gmr800