RAPD assay of wild-type olives in Turkey
Authors: M. Sesli and E.D. YeÃ?Â?enoÃ?Â?lu
Genetic similarities and distances between wild-type olives in Turkey were studied using an RAPD-PCR assay. Seven wild olive tree samples were collected from villages in Manisa and Izmir provinces. Genomic DNA was extracted from young leaves and the RAPD-PCR assay was used to generate RAPD markers. Sixty-five random primers ob.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr783
- DOI:
- 10.4238/vol9-2gmr783
Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation
Authors: A.D.B. Melo, H. Silveira, C. Bortoluzzi, L.J. Lara, C.A.P. Garbossa, G. Preis, L.B. Costa and M.H. Rostagno
In this study, we evaluated the effect of intestinal alkaline phosphatase (IAP) and sodium butyrate (NaBu) on lipopolysaccharide (LPS)-induced intestinal inflammation. Intestinal alkaline phosphatase and RelA/p65 (NF-κB) gene expressions in porcine jejunum explants were evaluated following exposure to sodium butyrate (Na.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048875
- DOI:
- 10.4238/gmr15048875
Protective effect and mechanism of probucol in the treatment of spinal cord injury
Authors: W.B. Zhu, Y.H. Wang, G.F. Sun and J.H. Wu
To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally inj.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.11
- DOI:
- 10.4238/2015.July.17.11
Abnormal gene expression profile reveals the common key signatures associated with clear cell renal cell carcinoma: a meta-analysis
Authors: H.J. Zhang, Z.Q. Sun, W.Q. Qian and L. Sheng
The aims of this study were to identify the common gene signatures of clear cell renal cell carcinoma (CCRCC), and to expand the respective protein-protein interaction networks associated with CCRCC regulation. For the latter, we utilized multiple gene expression data sets from the National Center for Biotechnology Information (NCBI) Gene Expression Omnib.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.7
- DOI:
- 10.4238/2015.March.27.7
The Caenorhabditis elegans genome: a multifractal analysis
Authors: P.E. VÃ?©lez, L.E. Garreta, E. MartÃ?Ânez, N. DÃ?Âaz, S. Amador, I. Tischer, J.M. GutiÃ?©rrez and P.A. Moreno
The Caenorhabditis elegans genome has several regular and irregular characteristics in its nucleotide composition; these are observed within and between chromosomes. To study these particularities, we carried out a multifractal analysis, which requires a large number of exponents to characterize scaling properties. We looked f.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr756
- DOI:
- 10.4238/vol9-2gmr756
Path analysis of agro-industrial traits in sweet sorghum
Authors: G.M.R. Lombardi, J.A.R. Nunes, R.A.C. Parrella, D.H.L. Teixeira1, A.T. Bruzi, N.N.L. Dur�£es and T.G. Fagundes
Sweet sorghum has considerable potential for ethanol production due to its succulent stalks that contain directly fermentable sugars. Since many traits need to be considered in the selection process to breed superior cultivars for ethanol production, then correlations between the traits might be of use to help the breeder define optimal improvement strate.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Case study of a patient presenting both type II bipolar affective disorder and Klinefelter syndrome
Authors: H. Delavenne, J.M. Khoury, F. Thibaut and F.D. Garcia
Klinefelter syndrome (KS) is the most common sex chromosomal disorder with an estimated prevalence of 1 in 500-1000. Increased incidences of anxiety, depression, substance abuse, psychotic and behavioral disorders, and sexual disorders have been reported in patients with KS. The aim of this case study was to report a case of a.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048872
- DOI:
- 10.4238/gmr15048872
Isolation and characterization of cancer stem cells from medulloblastoma
Authors: J. Liu, N. Chi, J.Y. Zhang, W. Zhu, Y.S. Bian and H.G. Chen
Brain cancer stem cells are a subset of tumor cells present in several types of brain tumor that evade treatment regimens and are responsible for tumor recurrence. Recent reports on several tumors have suggested that Hoechst 33342 dye exclusion is a powerful technique for isolating cancer stem cell-like side population (SP) cells. In the present study, we.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.13.15
- DOI:
- http://dx.doi.org/10.4238/2015.April.13.15
Association between growth differentiation factor-15 and chronic heart failure in coronary atherosclerosis patients
Authors: Z.D. Zhu and T. Sun
We explored the association between plasma growth differentiation factor 15 (GDF-15) levels and chronic heart failure (CHF) in coronary heart disease patients. We measured plasma GDF-15 and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in 269 untreated coronary heart disease patients (98 with CHF, 84 without CHF, and 87 control patients) us.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.8
- DOI:
- 10.4238/2015.March.27.8
A simple, fast, and inexpensive CTAB-PVP-silica based method for genomic DNA isolation from single, small insect larvae and pupae
Authors: W. Huanca-Mamani, D. Rivera-Cabello and J. Maita-Maita
In this study, we report a modified CTAB-PVP method combined with silicon dioxide (silica) treatment for the extraction of high quality genomic DNA from a single larva or pupa. This method efficiently obtains DNA from small specimens, which is difficult and challenging because of the small amount of starting tissue. Maceration with liquid nitrogen, phenol.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.8
- DOI:
- 10.4238/2015.July.17.8