Molecular characterization and expression analysis of purple acid phosphatase gene from pearl oyster Pinctada martensii
Authors: Q.H. Wang, Y. Jiao, X.D. Du, X.X. Zhao, R.L. Huang,Y.W. Deng and F. Yan
Purple acid phosphatases (PAPs), also known as type 5 acid phosphatases, are widely present in animals, plants, and fungi. In mammal, PAP was reported to participate in immune defense and bone resorption. In this study, the characteristics and potential functions of a PAP gene from pearl oyster Pinctada martensii (pm-PAP) were examined. The Pm-PAP cDNA wa.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.26.10
- DOI:
- 10.4238/2015.January.26.10
Mechanism of pingyangmycin-induced apoptosis of cultured human umbilical vein endothelial cells
Authors: Y.D. Huang, X. Tong, Q. Chen, S.W. Xia, Y. Zhuo, Z.H. Kang and X.Y. Xue
In this study, we investigated the effects of pingyangmycin (PYM) on the growth inhibition and apoptosis of human umbilical vein endothelial cells (HUVEC). In this study, we aimed to explore the optimal concentration of PYM to induce the apoptosis of HUVEC and to determine its mechanism of action. After treatment of HUVEC with.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029298
- DOI:
- 10.4238/gmr16029298
Genetic structure and diversity in the Dioscorea cayenensis/D. rotundata complex revealed by morphological and isozyme markers
Authors: E.A. Bressan, T. Briner Neto M.I. Zucchi R.J. Rabelloand E.A. Veasey
Of the 600 known yam species, only 10 are utilized as food, and the Dioscorea cayenensis/D. rotundata species complex is among the most cultivated. In Brazil, these species are commercially cultivated in the northeast region and are cultivated in the south and southeast regions as subsistence crops by traditional agriculturist.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.10
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.10
Conjugated linoleic acid-induced milk fat reduction associated with depressed expression of lipogenic genes in lactating Holstein mammary glands
Authors: L.Q. Han K. Pang H.J. Li S.B. Zhu L.F. Wang Y.B. Wang G.Q. Yang G.Y. Yang
The efficacy of conjugated linoleic acid (CLA) in diet supplements for milk fat reduction is well documented in several species. However, the mechanisms by which fatty acids regulate mammary lipogenesis remain largely unknown, especially with regard to gene expression of enzyme and regulators. In this study, 8 Holstein dairy cows in their mid-lactation pe.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.17.2
- DOI:
- 10.4238/2012.September.17.2
Molecular DNA identification of medicinal plants used by traditional healers in Malaysia
Authors: N.A.A. Aziz, M.I. Ahmad, D.M. Naim
Plants have been used throughout human history for food and medicine. However, many plants are toxic, and cannot easily be morphologically distinguished from non-toxic plants. DNA identification solves this problem and is widely used. Nonetheless, plant DNA barcode identification faces a number of challenges, and many studies .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.5
- DOI:
- 10.4238/2015.December.7.5
TNF-�± G-308A polymorphism is associated with insulin resistance: a meta-analysis
Authors: H.G. Wang, J. Yang, H. Han, F. Xu, Y. Bian, H. Zhang and J.L. Wang
Tumor necrosis factor-α (TNF-α) promoter polymorphisms has been reported to be associated with obesity and insulin resistance and gained widespread attention. However, results obtained so far are quite conflicting. We therefore performed a meta-analysis to address this issue, basing on 17 studies from electronic databases (MEDLINE an.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.26.11
- DOI:
- 10.4238/2015.January.26.11
CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue
Authors: J.B. Qian, H.B. Liu, Y. Zhu, F. Lu, Q.C. Yang and Y. Shen
The mRNA expression of cell adhesion molecule 1 (CADM1) and its clinicopathological significance in esophageal squamous cell carcinoma (ESCC) tissues were investigated. CADM1 mRNA and protein expression were detected in tissue samples from 50 patients with ESCC by reverse transcription-polymerase chain reaction (RT-PCR) and st.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029178
- DOI:
- 10.4238/gmr16029178
Study of the antimicrobial peptide indolicidin and a mutant in micelle medium by molecular dynamics simulation
Authors: C.A. Fuzo, J.R.M. Castro and L. Degr�¨ve
The antimicrobial peptide indolicidin (IND) and the mutant CP10A in hydrated micelles were studied using molecular dynamics simulations in order to observe whether the molecular dynamics and experimental data could be sufficiently correlated and a detailed description of the interaction of the antimicrobial peptides with a model of the membrane provided b.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr477
- DOI:
- 10.4238/vol7-4gmr477
Association study of circulating endothelial progenitor cells and plasma prostacyclin levels in pulmonary hypertension rats
Authors: Y. Song
The aim of this study was to investigate the correlation between circulating endothelial progenitor cell (EPC) levels and plasma prostacyclin (PGI2) concentrations in pulmonary hypertension (PH) rat models. Monocrotaline was used to induce PH, and the number of CD34/Flk-1-double-positive mononuclear cells in peripheral CD45-ne.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.11
- DOI:
- 10.4238/2014.January.21.11
Relationship between male sterility and �²-1,3-glucanase activity and callose deposition-related gene expression in wheat (Triticum aestivum L.)
Authors: H.Z. Liu, G.S. Zhang, W.W. Zhu, Q.S. Ba, N. Niu, J.W. Wang,S.C. Ma and J.S. Wang
In previous studies, we first isolated one different protein β-1,3-glucanase using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry from normal wheat (Triticum aestivum L.) and chemical hybridization agent-induced male sterility (CIMS) wheat. In this experiment, β-1,3-glucanase acti.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.26.12
- DOI:
- 10.4238/2015.January.26.12