Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia
Authors: D.D. Nabinger, L.E. Mazzoleni, G.B. Sander, F. Mazzoleni, M.C. Os�³rio, M.G. Klein, T.F. Rech, L. Basso da Silva, G.S. de Moraes, R.A. Cristovam, E.F. Nardelli, C.F.M. Francesconi and D. Simon
The aim of this study was to examine the effect of polymorphisms in the cytochrome P450 (CYP) 2C19 gene (CYP2C19) on the Helicobacter pylori eradication rate in Brazilian patients with functional dyspepsia. Adults diagnosed with functional dyspepsia based on the ROME III criteria and infected with H. pylori were recruited to this study. The patients were .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038734
- DOI:
- 10.4238/gmr.15038734
Microsporogenesis analysis validates the use of artificially tetraploidized Brachiaria ruziziensis in breeding programs
Authors: C.M.P. Paula, K.G. Figueiredo, F. Souza Sobrinho, F.R.G. Benites, L.C. Davide1and V.H. Techio
The genus Brachiaria contains species that have great economic importance in the Brazilian agricultural sector, as they enable cattle ranching on acid and poor soils with species that are resistant to spittlebugs and form crop-livestock-forest integration systems. The genus mainly consists of tetraploid (2n = 4x = 36) and apomictic species such as B. decu.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038737
- DOI:
- 10.4238/gmr.15038737
Physiological analysis and transcriptome comparison of two muskmelon (Cucumis melo L.) cultivars in response to salt stress
Authors: L.M. Wang, L.D. Zhang, J.B. Chen, D.F. Huang and Y.D. Zhang
Melon (Cucumis melo L.) is an important vegetable crop that ranks second in salt tolerance among the Cucurbitaceae. Previous studies on the two muskmelon cultivars ‘Bing XueCui’ (BXC) and ‘Yu Lu’ (YL) revealed that they had different characteristics under salt stress, but the molecular basis underlying their different physiological.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038738
- DOI:
- 10.4238/gmr.15038738
Classification and phylogenetic analysis of Chinese hawthorn assessed by plant and pollen morphology
Authors: S.L.Y. Ma and Y.M. Lu
The Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.) is uniquely originated in northern China. The ecological and horticultural importance of Chinese hawthorn is considerable and some varieties are valued for their fruit or medicine extracts. Its taxonomy and phylogeny remain poorly understood. Apart from general plant morphological traits.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038739
- DOI:
- 10.4238/gmr.15038739
Identification of a novel SLC45A2 mutation in albinism by targeted next-generation sequencing
Authors: J.J. Xue, J.F. Xue, H.Q. Xue, Y.Y. Guo, Y. Liu and N. Ouyang
Albinism is a diverse group of hypopigmentary disorders caused by multiple-genetic defects. The genetic diagnosis of patients affected with albinism by Sanger sequencing is often complex, expensive, and time-consuming. In this study, we performed targeted next-generation sequencing to screen for 16 genes in a patient with albinism, and identified 21 genet.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038743
- DOI:
- 10.4238/gmr.15038743
Single base substitution causing the fragrant phenotype and development of a type-specific marker in aromatic coconut (Cocos nucifera
Authors: A. Vongvanrungruang, C. Mongkolsiriwatana, T. Boonkaew, O. Sawatdichaikul, K. Srikulnath and S. Peyachoknagul
The fragrance gene, betaine aldehyde dehydrogenase 2 (Badh2), has been well studied in many plant species. The objectives of this study were to clone Badh2 and compare the sequences between aromatic and non-aromatic coconuts. The complete coding region was cloned from cDNA of both aromatic and non-aromatic coconuts. The nucleotide sequences were highly ho.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038748
- DOI:
- 10.4238/gmr.15038748
Association between peptidyl arginine deiminase 4 (PADI4)-104C/T polymorphism and rheumatoid arthritis: a meta-analysis in the Chinese population
Authors: L.L. Gong, J. Chang and Y.M. Yang
The correlation between the -104C/T polymorphism in the peptidyl arginine deiminase 4 (PADI4) gene and rheumatoid arthritis (RA) risk has been analyzed in several studies. However, the results are inconclusive and remain to be confirmed in several ethnic groups. The effect of the PADI4-104C/T polymorphism on RA risk in the Chinese population was evaluated.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038750
- DOI:
- 10.4238/gmr.15038750
Biometric analysis of arabica coffee grown in low potassium nutrient solution under greenhouse conditions
Authors: W.M. Moura, Y.J.B. Soares, A.T. Amaral J�ºnior, G.A. Gravina, L.D. Barili and H.D. Vieira
Genetic parameters and associations between morpho-agronomic traits and nutritional efficiencies of arabica coffee cultivars were estimated to identify promising traits to assist in the selection of coffee genotypes efficient in potassium use, under limiting conditions of this nutrient. The experiment was conducted in a greenhouse with 20 arabica coffee c.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038753
- DOI:
- 10.4238/gmr.15038753
Identification of SNPs in growth-related genes in Colombian creole cattle
Authors: R. Martinez, J.F. Rocha, D. Bejarano, Y. Gomez, Y. Abuabara and J. Gallego
Colombian creole cattle have important adaptation traits related to heat tolerance and reproductive and productive efficiency. Romosinuano (ROMO) and Blanco Orejinegro (BON) are the most common breeds used by Colombian cattle breeders. Growth traits are of prime importance in these animals, which are mainly raised for beef production. Genes encoding growt.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038762
- DOI:
- 10.4238/gmr.15038762
Development of the first polymorphic microsatellite markers for the Roman snail Helix pomatia L., 1758 (Helicidae) and cross-species amplification within the genus Helix
Authors: A.M. Krapal, O.P. Popa, E.I. Iorgu, L.B. Cojocaru, A.F. Popa and L.O. Popa
The terrestrial snail Helix pomatia (Gastropoda: Stylommatophora: Helicidae) is one of the largest gastropod species in Europe. This species is strictly protected in some European Union countries; however, at the same time, it is also farmed and commercialized for human consumption. Here, we describe 11 microsatellite markers that are very useful in popul.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038817
- DOI:
- 10.4238/gmr.15038817