Association of plasma B-type natriuretic peptide concentration with myocardial infarct size in patients with acute myocardial infarction
Authors: J.M. Niu, Z.L. Ma, C. Xie and Z.Q. Zhang
B-type natriuretic peptide (BNP) is widely used in the treatment of early-stage heart failure and coronary heart disease. In this study, the association of plasma BNP concentration with myocardial infarct (MI) size in patients with acute myocardial infarction (AMI) was investigated. Eighty patients with AMI were enrolled in th.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.21.6
- DOI:
- 10.4238/2014.February.21.6
Association of interleukin-6 gene polymorphisms and circulating levels with keloid scars in a Chinese Han population
Authors: X.J. Zhu, W.Z. Li, H. Li, C.Q. Fu and J. Liu
The aim of the present study is to explore the effect of IL-6 gene polymorphisms on the development of keloid scar (KS) in the Chinese Han population. Genotyping of IL-6 was performed by the polymerase chain reaction (PCR), followed by restriction fragment length polymorphism assays (PCR-RFLP). Serum level of IL-6 was measured.. Read More»
- Genet. Mol. Res. 16(2):
cDNA-AFLP transcriptional profiling reveals genes expressed during flower development in Oncidium Milliongolds
Authors: X. Qian, M.J. Gong*, C.X. Wang and M. Tian
The flower developmental process, which is crucial to the whole lifecycle of higher plants, is influenced by both environmental and endogenous factors. The genus Oncidium is commercially important for cut flower and houseplant industry and is ideal for flower development studies. Using cDNA-amplified restriction fragm.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.21.5
- DOI:
- 10.4238/2014.February.21.5
A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil
Authors: A.C.S. Ferreira, M.P.A. Orlandi, V.C. Oliveira, F.S.V. Malta,F.A. Caxito, K.B. Gomes, E.R. Valadares and A.L.B. Godard
In view of the serious consequences of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency and the absence of information about its incidence in the Brazilian population, we examined the frequency of the A985G mutation in the MCAD gene. A retrospective analysis was made of data on 1722 individuals (844 females) genotyped for.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2gmr579
- DOI:
- 10.4238/vol8-2gmr579
Prevalence of human papillomavirus, Chlamydia trachomatis, and Trichomonas vaginalis infections in Amazonian women with normal and abnormal cytology
Authors: E. Costa-Lira, A.H.V.L. Jacinto, L.M. Silva, P.F.R. Napole�£o,R.A.A. Barbosa-Filho, G.J.S. Cruz, S. Astolfi-Filho and C.M. Borborema-Santos
Sexually transmitted infections are an important cause of morbidity among sexually active women worldwide, and have been implicated as cofactors in the pathogenesis of cervical cancer. We investigated the prevalence of human papillomavirus (HPV), Chlamydia trachomatis (CT), and Trichomonas vaginalis (TV), and accessed the dive.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029626
- DOI:
- 10.4238/gmr16029626
Biochip analysis of prostate cancer
Authors: M.Q. Fan, P.X. Wang, J.Y. Feng, Y. Xiao and C.B. Huang
Microarray expression analysis was used to forecast the roles of differentially co-expressed genes (DCG) and DCG and links in the pathogenesis of prostate cancer. In addition, we demonstrate that the relationship between transcriptional factors (TFs) and their targets can be considered a key factor in determining the differenc.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.6
- DOI:
- 10.4238/2014.January.10.6
Use of weaning management group as a random effect for a more robust estimation of genetic parameters for post-weaning traits in Nellore cattle
Authors: V.B. Pedrosa, J.P. Eler, J.B.S. Ferraz and E. Groeneveld
Data from 69,525 animals were used to compare two types of analyses, one of them having the weaning management group (WEMANG) included as an effect in the contemporary group (F_WEMANG) and the other considering the weaning management group as a random effect, not related to the mathematical model (R_WEMANG) for post-weaning tr.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.February.21.7
- DOI:
- 10.4238/2014.February.21.7
Treatment of silicosis with hepatocyte growth factor-modified autologous bone marrow stromal cells: a non-randomized study with follow-up
Authors: W.W. Liu, H.X. Wang, W. Yu, X.Y. Bi, J.Y. Chen, L.Z. Chen, L. Ding, D.M. Han, Z.K. Guo and Y.X. Lei
Pulmonary silicosis is an irreversible and untreatable disease that is characterized by interstitial lesions and perpetual fibrosis in the lungs. This study was performed to determine whether mesenchymal stem cells (MSCs) and hepatocyte growth factor (HGF) could exhibit therapeutic effects on human silicosis. This non-randomized uncontrolled trial compris.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.7
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.7
Validation of a reaction volume reduction protocol for analysis of Y chromosome haplotypes targeting DNA databases
Authors: C.A. Souza, T.C. Oliveira, S. Crovella, S.M. Santos, K.C.N. Rab�ªlo, E.P. Soriano, M.V.D. Carvalho, A.F. Caldas Junior, G.G. Porto, R.I.C. Campello, A.A. Antunes, R.A. Queiroz and S.M. Souza
The use of Y chromosome haplotypes, important for the detection of sexual crimes in forensics, has gained prominence with the use of databases that incorporate these genetic profiles in their system. Here, we optimized and validated an amplification protocol for Y chromosome profile retrieval in reference samples using lesser .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029652
- DOI:
- 10.4238/gmr16029652
Association between a single nucleotide polymorphism of the XRCC1 gene and hepatocellular carcinoma susceptibility in the Chinese Han population
Authors: X.F. Li, Y.X. Chen, W.W. Ye, X.F. Tao, J.H. Zhu, S. Wu and L.Q. Lou
The human X-ray repair cross-complementing protein 1 (XRCC1) gene is a potentially gene determining hepatocellular carcinoma (HCC) susceptibility. The purpose of this study was to evaluate the association between XRCC1 and susceptibility to HCC. The association of XRCC1 polymorphisms with HCC susceptibility was investigated in.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.7
- DOI:
- 10.4238/2014.January.10.7