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Animal Genetics   Research Article

Polymorphisms of AluI and Hin1I loci of the IGF-1R gene and their genetic effects on growth traits in Bian chickens

Authors: P.F. Wu, D. Wang, C.F. Jin, X.Q. Zhang, H.Q. Wu, L. Zhang, F.X. Ding, K. Z. Xie and G.X. Zhang

Growth traits are important economic traits in broiler chicken production. AluI and Hin1I loci are two restriction sites, which are respectively located in exons 2 and 3 of the IGF-1R gene. These two loci are significantly related to the growth traits in Jinghai Yellow chickens. In this study, a correlation analysis was perfor.. Read More»

Genet. Mol. Res. 16(2):
gmr16029619
DOI:
10.4238/gmr16029619
Microbial Genetics   Research Article

Protection against Taenia pisiformis larval infection induced by a recombinant oncosphere antigen vaccine

Authors: L. Chen, D.Y. Yang, Y. Xie , X. Nong, X. Huang , Y. Fu, X.B. Gu, S.X. Wang, X.R. Peng and G.Y. Yang

Taenia pisiformis larvae cause significant health problems to rabbits. At present, it is not known whether the recombinant antigen from the T. pisiformis oncosphere is able to confer protective immunity against T. pisiformis larval infection. The full-length cDNA was cloned into a pET32a (+) vector, .. Read More»

Genet. Mol. Res. 13(3):
2014.February.13.14
DOI:
10.4238/2014.February.13.14
Plant Genetics   Review Article

Genotype x environment interaction on experimental hybrids of chili pepper

Authors: N.S.S. Cabral, A.M. Medeiros, L.G. Neves, C.P. Sudr�©, S. Pimenta, V.J. Coelho, M.E. Serafim and R. Rodrigues

In Brazil, cultivation of hybrid plants comprise near 40% of the area grown with vegetables. For Capsicum, hybrids of bell and chili peppers have already exceeded 50% and over 25% of all are commercialized seeds. This study aimed to evaluate new pepper hybrids in two environments, Cáceres, MT, and Campos dos Goytacazes,.. Read More»

Genet. Mol. Res. 16(2):
gmr16029551
DOI:
10.4238/gmr16029551
Animal Genetics   Research Article

Study of different structures of additive genetic groups to increase the efficiency of genetic selection in beef cattle

Authors: G.A. Oliveira Junior

The structure of genetic groups is a technique that allows animals with unknown paternity to be included in genetic evaluation programs. The ways these groups are formed are still arbitrary, making it important to study different formation strategies for genetic groups, aiming for a suitable framework for the genetic evaluatio.. Read More»

Genet. Mol. Res. 13(1):
2014.January.10.1
DOI:
10.4238/2014.January.10.1
Plant Genetics   Research Article

Genetic variability of Brazilian Indian landraces of Arachis hypogaea L.

Authors: F.O. Freitas, M.C. Moretzsohn, J.F.M. Valls

The Kayabi Indians who inhabit the Xingu Indigenous Park, located in West Central Brazil, have grown and managed peanuts for a long time. A great number of landraces are being maintained by these tribes and some of this germplasm has morphological traits that exceed the variation described in the taxonomic literature. Here, we.. Read More»

Genet. Mol. Res. 6(3):
Animal Genetics   Research Article

Acute heat stress and dietary methionine effects on IGF-I, GHR, and UCP mRNA expression in liver and muscle of quails

Authors: A.P. Del Vesco, E. Gasparino, V. Zancanela, D.O. Grieser, S.E.F. Guimar�£es, C.S. Nascimento, D.M. Voltolini, J. Constantin and F.S. Gasparin

This study evaluated the expression of insulin-like growth factor I (IGF-I), growth hormone receptor (GHR), and uncoupling protein (UCP) mRNA in muscle and liver of quails that were in thermal comfort or exposed to heat stress and that were fed diets with or without methionine supplementation. Meat quails were fed a diet that .. Read More»

Genet. Mol. Res. 13(3):
2014.February.13.12
DOI:
10.4238/2014.February.13.12
Human Genetics   Research Article

Correlation of E6 and E7 levels in high-risk HPV16 type cervical lesions with CCL20 and Langerhans cells

Authors: B. Jiang and M. Xue

The human papillomavirus (HPV)16 E6 and E7 correlation with chemokine ligand (CCL)20 expression and Langerhans cells (LCs) in cervical lesions was investigated. We enrolled 43 patients with surgically treated cervical lesions from the Department of Gynecology in our hospital, and 20 controls without cervical lesions. Subjects were divided by pathology: HP.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.8
DOI:
http://dx.doi.org/10.4238/2015.September.8.8
Human Genetics   Research Article

BCR-ABL1 transcript types showed distinct laboratory characteristics in patients with chronic myeloid leukemia

Authors: A.P. Vasconcelos, I.F. Azevedo, F.C.B.C. Melo, W.B. Neves, A.C.A.C. Azevedo and R.A.M. Melo

In chronic myeloid leukemia (CML) two main types of messenger RNA (e14a2 and e13a2) can be produced by BCR-ABL1 gene rearrangement. Due to conflicting results, the clinical value of these transcripts remains controversial. The aim of this study was to identify associations of e14a2 and e13a2 transcripts with laboratory variabl.. Read More»

Genet. Mol. Res. 16(2):
gmr16029541
DOI:
10.4238/gmr16029541
Animal Genetics   Research Article

Tissue- and breed-specific expression of the chicken fat mass- and obesity-associated gene (FTO)

Authors: C. Song, W.T. Song, J.T. Shu, Z.Y. Tao, W.Q. Zhu, C. Di and H.F. Li

The fat mass- and obesity-associated gene (FTO) is involved in energy metabolism, but little is known about the chicken FTO gene. The objective of the current study was to detect chicken FTO expression patterns in the hypothalamus, liver, and skeletal muscle during development, and analyze the effects of age and breed on FTO expression. Real-time quantita.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.11
DOI:
http://dx.doi.org/10.4238/2015.September.8.11
Medical Genetics   Research Article

Association between angiogenic growth factor genetic polymorphisms and the risk of osteosarcoma

Authors: H.F. Zhang, J.P. Yan, Y.S. Zhuang and G.Q. Han

The aim of this study was to assess the role of the VEGF -2578C/A, +936C/T, and -460T/C gene polymorphisms in the development of osteosarcoma. A total of 182 patients with osteosarcoma and 182 age- and gender-matched healthy controls were enrolled into our study during January 2011 and December 2013. Genotype frequencies of the VEGF -2578C/A and -460T/C a.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.14
DOI:
http://dx.doi.org/10.4238/2015.September.8.14