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Medical Genetics   Research Article

Effect of chronic hypoxia on penile erectile function in rats

Authors: D.P. Yu, X.H. Liu and A.Y. Wei

We examined the relationship between chronic hypoxia and erectile dysfunction in rat and its possible pathogenic mechanism. Forty-eight white male adult Sprague-Dawley rats were randomly divided into a test group and a control group. In accordance with the experimental time (2, 6, and 10 weeks), each group was divided into 3 subgroups, with 8 rats in each.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.8.9
DOI:
http://dx.doi.org/10.4238/2015.September.8.9
Human Genetics   Research Article

A proposed selection index for feedlot profitability based on estimated breeding values

Authors: R.R. van der Westhuizen and J. van der Westhuizen

It is generally accepted that feed intake and growth (gain) are the most important economic components when calculating profitability in a growth test or feedlot. We developed a single post-weaning growth (feedlot) index based on the economic values of different components. Variance components, heritabilities and genetic corre.. Read More»

Genet. Mol. Res. 8(2):
vol8-2gmr599
DOI:
10.4238/vol8-2gmr599
Microbial Genetics   Research Article

Antimicrobial activity and chemical composition of Brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide

Authors: L.C.T. Thiesen, E.Y.Y. Sugauara, V. Te?¡evi??, J. Glamo?lija, M. Sokovi??, J.E. Gon?§alves, Z.C. Gazim, G.A. Linde and N.B. Colauto

Brunfelsia genus is traditionally utilized in popular medicine due to its antibacterial and antifungal properties to name but a few. However, studies on the antimicrobial activity of Brunfelsia uniflora flower oleoresin have not been found yet. This study aimed to evaluate the chemical composition and antimicrobial activity of.. Read More»

Genet. Mol. Res. 16(2):
gmr16029548
DOI:
10.4238/gmr16029548
Medical Genetics   Research Article

Differentiation of Nijmegen breakage syndrome from Fanconi anemia

Authors: V.B. Rao, K. Ghosh, L. Kerketta, S. Korgaonkar

Nijmegen breakage syndrome (NBS) is a rare auto-somal recessive condition with chromosomal instability. Clinical and biological overlap between Fanconi anemia and ataxia telangiectasia has been reported. We report two cases of NBS born to consanguineous parents. Case one had NBS and Falconi anemia clinical features but relativ.. Read More»

Genet. Mol. Res. 6(3):
Plant Genetics   Research Article

Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population....

Authors: H.M. Wang, N.F. Li, J. Hong, L. Zhou and J.H. Chang

Genetic variation is thought to contribute to etiology of metabolic syndrome (MS). Neural precursor cell expressed developmentally downregulated 4-like gene (NEDD4L) is a candidate gene for MS. This study investigated the relationship between variations of NEDD4L and MS in the Kazakh, which is an ideal population to study the genetic mechanisms of complex.. Read More»

Genet. Mol. Res. 13(1):
2014.January.8.1
DOI:
10.4238/2014.January.8.1
Human Genetics   Research Article

Genotoxicity testing of Ambelania occidentalis (Apocynaceae) leaf extract in vivo

Authors: L.S. Castro, F.F. Perazzo and E.L. Maistro

Ambelania occidentalis is routinely used in folk medicine for treating gastrointestinal disorders, even though there have been no safety trials. We evaluated the genotoxic potential of hydro-alcoholic extracts of this plant in mice; induced DNA damage was assessed in peripheral blood leukocytes and micronucleus induction was a.. Read More»

Genet. Mol. Res. 8(2):
vol8-2gmr588
DOI:
10.4238/vol8-2gmr588
Plant Genetics   Research Article

Industrial tomato lines: morphological properties and productivity

Authors: J.V.M. Peixoto, C. de M.S. Neto, L.F.C. Campos, W. de S. Dourado, A.P.O. Nogueira and A. dos R. Nascimento

The tomato is the second most produced vegetable in the world, with significant participation in the human diet. In addition, the production of tomatoes generates jobs and family income. The availability of improved cultivars that provide greater profitability to the producer and satisfactorily meets the needs of the fresh fru.. Read More»

Genet. Mol. Res. 16(2):
gmr16029540
DOI:
10.4238/gmr16029540
Human Genetics   Research Article

A patient with ascending aortic dilatation, similar to phenotypes of connective tissue disorders

Authors: S.T. Onrat, M. Emmiler, Y. S?±vac?±, Z. S?¶ylemez,A. ??zg?¶z, N. Imirzal?±o??lu

We report on the clinical and molecular findings of a patient who presented alopecia, epicanthus, micrognathia, retrognathia, high arched palate, hypertelorism, Chiari type I malformation, mixed-type hearing loss but with normal heartbeat Q-T interval, malformed earlobes, down-slanted palpebral fissures, downturned corners of .. Read More»

Genet. Mol. Res. 8(2):
Plant Genetics   Research Article

Sample size for estimation of direct effects in path analysis of corn

Authors: M. Toebe, A. Cargnelutti Filho, L. Storck and A.D. L?ºcio

The objective of this study was to assess the sample size required for estimating the direct effects of explanatory variables on the grain yield of corn in the combinations formed by three types of hybrids x two harvests x nine scenarios of explanatory variables x two types of path analyses x four levels of accuracy. A total o.. Read More»

Genet. Mol. Res. 16(2):
gmr16029523
DOI:
10.4238/gmr16029523
Plant Genetics   Research Article

Cytogenetic characterization of Rhamdia quelen (Siluriformes, Heptapteridae) from the Bodoquena Plateau, Mato Grosso do Sul, Brazil

Authors: V.P.O. Moraes, S.S. Cereali, O. Froehlich, A.L. Dias

We made a cytogenetic study of the fish Rhamdia quelen collected from the Bodoquena Plateau, an isolated national park region in Mato Grosso do Sul State, Brazil. The diploid number was 2n = 58, with 36 metacentric + 16 submetacentric + 6 subtelocentric chromosomes. We found one to three B chromosomes, which were metacentric a.. Read More»

Genet. Mol. Res. 6(3):