Polymorphisms in interleukin-6 and interleukin-10 may be associated with risk of preeclampsia
Authors: D.M. Fan, Y. Wang, X.L. Liu, A. Zhang and Q. Xu
Preeclampsia is a common condition unique to pregnant women. Previous studies have suggested that several cytokines may contribute to defective placental invasion and endothelial damage in this condition. We investigated the influence of four single nucleotide polymorphisms (SNPs) in the promoters of IL-6 (-572G/C, -597G/A, an.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018588
- DOI:
- 10.4238/gmr16018588
C3435T polymorphism of the MDR1 gene is not associated with blood levels of hypothalamus-pituitary-adrenal axis hormones in healthy male subjects
Authors: A. Suzuki, Y. Matsumoto, T. Shirata, K. Goto, M. Enokido, K. Otani
In vitro studies have shown that multidrug resistance protein 1 (MDR1) has an affinity for cortisol; however, in vivo association studies on the relationship between MDR1 gene polymorphisms and blood cortisol levels have produced inconsistent results. Therefore, we examined the effects of the C3435T polymorphism of the MDR1 ge.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019447
- DOI:
- 10.4238/gmr16019447
MicroRNA-122 is involved in oxidative stress in isoniazid-induced liver injury in mice
Authors: L. Song, Z.R. Zhang, J.L. Zhang, X.B. Zhu, L. He, Z. Shi, L. Gao, Y. Li, B. Hu and F.M. Feng
Many studies have shown that the pathogenesis of liver injury includes oxidative stress. MicroRNA-122 may be a marker for the early diagnosis of drug-induced liver injury. However, the relationship between microRNA-122 and oxidative stress in anti-tuberculosis drug-induced liver injury remains unknown. We measured changes in tissue microRNA-122 levels and.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.22
- DOI:
- 10.4238/2015.October.26.22
Digital expression analysis of the genes associated with salinity resistance after overexpression of a stress-responsive small GTP-binding RabG protein in peanut
Authors: J.M. Sui, G. Li, G.X. Chen, M.Y. Yu, S.T. Ding, J.S. Wang and L.X. Qiao
The Rab protein family is the largest family of the small GTP-binding proteins. Among them, the RabG genes are known to be responsive to abiotic stresses, but the molecular mechanisms of the stress responses mediated by RabG genes in plants is poorly understood. To investigate the molecular mechanism of AhRabG gene in peanut, .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019432
- DOI:
- 10.4238/gmr16019432
Microbial diversity in raw milk and traditional fermented dairy products (Hurood cheese and Jueke) from Inner Mongolia, China
Authors: M.L. Gao, H.M. Hou, X.X. Teng, Y.L. Zhu, H.S. Hao and G.L. Zhang
Hurood cheese (HC) and Jueke (Jk) are 2 traditional fermented dairy products produced from raw milk (RM) in the Inner Mongolia region of China. They have a long history of production and consumption. The microbial compositions of RM, HC, and Jk vary greatly, and are influenced by their geographical origins and unique processin.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019451
- DOI:
- 10.4238/gmr16019451
Changes on microsatellites of expressed sequence tag of sugarcane (Saccharum spp) during vegetative propagation
Authors: R. Augusto, R.C. Maranho, C.A. Mangolin, J.C. Bespalhok Filho and M.F.P.S. Machado
The reduction in sugarcane productivity in subsequent cutting stages may be related to a gradual decrease of the allele number and mean observed heterozygosity (HO) in the sugarcane ratoon. This hypothesis was tested assessing the number of alleles and HO values in 10 expressed sequence tag microsatellites (Est-SSR loci) of th.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019519
- DOI:
- 10.4238/gmr16019519
Expression of the stem cell factor in fibroblasts, endothelial cells, and macrophages in periapical tissues in human chronic periapical diseases
Authors: S.Q. Shen, R. Wang and S.G. Huang
Stem cell factor (SCF), an important stem cell cytokine, has multiple functions. Fibroblasts (FBs), mature mast cells, endothelial cells (ECs), and eosinophil granulocytes can produce SCF in the inflammatory process. Therefore, we aimed to observe SCF expression in FBs, ECs, and macrophages (MPs) in periapical tissues in human.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019394
- DOI:
- 10.4238/gmr16019394
MiR-214 regulates oral cancer KB cell apoptosis through targeting RASSF5
Authors: T.K. Li, K. Yin, Z. Chen, Y. Bao and S.X. Zhang
Ras association domain family member 5 (RASSF5), a member of the Ras association domain family, induces cell apoptosis by phosphorylating FOXO3a, which triggers target gene BIM (pro-apoptotic factor) activation. MiR-214 is overexpressed in oral cancer tissue, indicating its possible involvement in oral cancer pathogenesis. Bio.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019327
- DOI:
- 10.4238/gmr16019327
Establishment and application of molecular ID in the main inbred lines of Chinese cabbage
Authors: X.X. Zhang, X.B. Tang, Y. Liu and Y.W. Zhang
Chinese cabbage is an important cruciferous vegetable in China. The differences in the morphology and other characteristics of the different varieties of Chinese cabbage are generally caused by their different genes. Using the simple sequence repeat (SSR) DNA molecular markers is an effective way to identify different genotype.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019144
- DOI:
- 10.4238/gmr16019144
Selection of experimental strawberry (Fragaria x ananassa) hybrids based on selection indices
Authors: S.D. Vieira, D.C. de Souza, I.A. Martins, G.H.M.R. Ribeiro, L.V. Resende, A.K.L. Ferraz, A.G. Galv�£o and J.T.V. de Resende
The strawberry (Fragaria x ananassa Dutch.), is the only vegetable belonging to the rosacea family. All strawberry species have now emerged from wild species and belong to the genus Fragaria, being that this genus presents more than 45 described species, and only 11 are considered natural species. Due to the octoploid nature o.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019052
- DOI:
- 10.4238/gmr16019052