Genetic polymorphisms in �²-defensin II gene in Amazon sheep from Brazil
Authors: B.B. Souza, E.M. Barbosa, J.S.N. Azevedo, J.E.G. Campelo,L.F.S. Rodrigues, L.M.L. Pinheiro, S.C.B Silva, A.S. Schierholt, P.H. Souza, E.C. Gon�§alves and E. Silva Filho
The northern region of Brazil produces a large number of sheep, with Pará being the largest sheep breeding state in the region. In the Amazon region, livestock production is a challenge due to the high diversity of pathogens affecting humans and animals. Defensins are antimicrobial peptides acting as a first barrier aga.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.24
- DOI:
- 10.4238/2015.October.19.24
Molecular characterization of accessions of Cratylia argentea (Camaratuba) using ISSR markers
Authors: G.A. Luz, S.O. Gomes, R.B. Araujo Neto, M.S.C.B. Nascimento and P.S.C. Lima
Cratylia argentea (Desv.) Kuntze (Fabaceae) is a drought-tolerant, perennial legume found primarily in Brazil, Bolivia, and Peru. The shrub is well adapted to acid soils and exhibits high productivity and nutritional value, characteristics that would favor its use as a dry season animal forage supplement in semiarid r.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.12
- DOI:
- 10.4238/2015.November.25.12
Genetic variability in local Brazilian horse lines using microsatellite markers
Authors: A.C.M. Silva, S.R. Paiva, M.S.M. Albuquerque, A.A. Egito, S.A. Santos, F.C. Lima, S.T. Castro, A.S. Mariante, P.S. Correa and C.M. McManus
Genetic variability at 11 microsatellite markers was analyzed in five naturalized/local Brazilian horse breeds or genetic groups. Blood samples were collected from 328 animals of the breeds Campeira (Santa Catarina State), Lavradeira (Roraima State), Pantaneira (Pantanal Mato-Grossense), Mangalarga Marchador (Minas Gerais Stat.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.4
- DOI:
- 10.4238/2012.April.10.4
Genetic diversity analysis of faba bean (Vicia faba L.) germplasms using sodium dodecyl sulfate-polyacrylamide gel electrophoresis
Authors: W.W. Hou1*, X.J. Zhang2*, J.B. Shi1 and Y.J. Liu1
To investigate genetic diversity and relationships of 101 faba bean (Vicia faba L.), landraces and varieties from different provinces of China and abroad were analyzed by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis (PAGE). A total of 2625 unambiguous and stable bands from 101 germplasms were detected, and 36 different bands were classi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.15
- DOI:
- 10.4238/2015.October.29.15
Association of CD226 polymorphisms with the susceptibility to type 1 diabetes in Chinese children
Authors: J.S. Xi, C.L. Nie, J. Wang, Y. Ma and A.H. Ma
Polymorphisms in the CD226 gene have been reported to be associated with autoimmune diseases. The aim of our study was to investigate the association between two single nucleotide polymorphisms (SNPs) (rs763361 and rs727088) in the CD226 gene and the risk for developing type 1 diabetes (T1D) in Chinese Han children. This case-.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.13
- DOI:
- 10.4238/2015.November.25.13
NLRP3 rs35829419 polymorphism is associated with increased susceptibility to multiple diseases in humans
Authors: Q. Zhang, H.W. Fan, J.Z. Zhang, Y.M. Wang and H.J. Xing
Using a meta-analysis framework, we investigated the association between the NLRP3 rs35829419 polymorphism and increased susceptibility to diverse diseases in humans. Relevant published studies were identified through a comprehensive and systematic electronic search, using the following scientific literature databases: Science Citation Index, the Cochrane.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.17
- DOI:
- 10.4238/2015.October.29.17
Angiotensin-converting enzyme gene I/D dimorphism does not play a major role in the susceptibility of Malaysian systemic lupus erythematosus patients
Authors: L.-H. Lian, T.-P. Lau, A.-S. Ching and K.-H. Chua
Systemic lupus erythematosus (SLE) is an autoimmune disease that causes systemic damage, involving auto-reactive antibodies and over-deposition of immune complexes. Susceptibility to SLE is believed to be multifactorial, and genetics is one of the proven etiological factors; it can affect SLE development, severity and prognosi.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.2
- DOI:
- 10.4238/2012.April.10.2
Molecular barcoding of venomous snakes and species-specific multiplex PCR assay to identify snake groups for which antivenom is available in Thailand
Authors: A. Supikamolseni1,2, N. Ngaoburanawit3, M. Sumontha4, L. Chanhome5,S. Suntrarachun6, S. Peyachoknagul2,7 and K. Srikulnath1,2,7
DNA barcodes of mitochondrial COI and Cytb genes were constructed from 54 specimens of 16 species for species identification. Intra- and interspecific sequence divergence of the COI gene (10 times) was greater than that of the Cytb gene (4 times), which suggests that the former gene may be a better marker than the latter for species delimitation in snakes.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.18
- DOI:
- 10.4238/2015.October.29.18
Sex differential marker FD for rapid sex identification of Litsea cubeba
Authors: Q. Wu, Y. Chen, Y. Wang and L. Lin
Litsea cubeba is an important economic tree in China. Sex identification of the species is required to reduce breeding costs. Molecular biology is an ideal method to achieve this aim because of the lack of morphological differences between male and female plants, especially at the seedling stage. Sequence-related amplified pol.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.21.1
- DOI:
- 10.4238/2015.October.21.1
Alternative splicing isoform of T cell factor 4K suppresses the proliferation and metastasis of non-small cell lung cancer cells
Authors: Y.C. Fan, L. Min, H. Chen and Y.L. Liu
The Wnt pathway has been implicated in the initiation, progression, and metastasis of lung cancer. T cell factor 4, a member of TCF/LEF family, acts as a transcriptional factor for Wnt pathways in lung cancer. Increasing amounts of evidence have shown that TCF-4 has multiple alternative splicing isoforms with transactivation or transrepression activity to.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.29.20c
- DOI:
- 10.4238/2015.October.29.20c