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Animal Genetics   Research Article
Polymorphism in the Beta Casein Gene and analysis of milk characteristicsin Gir and Guzer�¡ dairy cattle

Authors: A.H.N. Rangel, L.G. Zaros, T.C. Lima, L.H.F. Borba, L.P. Novaes, L.F.M. Mota and M.S. Silva

Several human health problems have been related to the allergenic constitution of bovine milk due to the body’s immune reaction to milk proteins. It is necessary find solutions to minimize the occurrence of such reactions, given the importance of milk as a source of animal protein. The aim of this study was to evaluate t.. Read More»

Genet. Mol. Res. 16(2): gmr16029592

DOI: 10.4238/gmr16029592

Human Genetics   Case Reports
Cytogenetic aspects of a canine breast carcinosarcoma - a case report

Authors: C.S.D. Morais, P.R.A.M. Affonso, J.A. Bitencourt and A.A. Wenceslau

This study searched a rare and aggressive type of cancer in dogs and humans, the breast carcinosarcoma. Both clinical and pathological traits of mammary carcinosarcomas in dogs are similar to humans, such as infrequent occurrence, fast tumor growth, and unfavorable prognosis when compared to carcinomas. Other possible alterati.. Read More»

Genet. Mol. Res. 16(2): gmr16029433

DOI: 10.4238/gmr16029433

Animal Genetics   Review Article
Effects of cell death-inducing DFF45-like effector B on meat quality traits in Berkshire pigs

Authors: G.E. Yu, S. Kwon, J.H. Hwang, S.M. An, D.H. Park, D.G. Kang, T.W. Kim, I.-S. Kim, H.C. Park, J. Ha and C.W. Kim

Cell death-inducing DFF45-like effector (CIDE) B is a member of the CIDE family of apoptosis-inducing factors. In the present study, we detected a single nucleotide polymorphism (SNP), c.414G>A, which corresponds to the synonymous SNP 414Arg, in CIDE-B in the Berkshire pigs. We also analyzed the relationships between the CI.. Read More»

Genet. Mol. Res. 16(2): gmr16029408

DOI: 10.4238/gmr16029408

Human Genetics   Research Article
Effect of 1,25(OH)2D3 on the proliferation of human mesangial cells and their expression of Ki67

Authors: D. Zhao, C.-J. Zhang, R. Yang, J.-P. Chen, L. Ma, G. Liu and X.-P. Yang

Previous studies have found that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3 or VD3] exerts many biological effects, including the inhibition of cell proliferation and induction of apoptosis, but its mechanism of action remains unclear. The goal of our investigation was to explore the effects of 1,25(OH)2D3 on the proliferation of c.. Read More»

Genet. Mol. Res. 16(2): gmr16029191

DOI: 10.4238/gmr16029191

Plant Genetics   Research Article
Analysis of protein profile of tomato root infected with Fusarium oxysporum f. sp lycopersici

Authors: T.D. Silva, C.M.A. Almeida, C.B. Malafaia, L.M.S. Oliveira, M.V. Silva and M.T.S. Correia

Fusarium wilt caused by Fusarium oxysporum f. sp lycopersici (Fol) is one of the main diseases affecting tomatoes. The BHRS 2,3 genotype of tomato is, however, resistant to this disease. A proteomic approach was used to understand the defense mechanisms of this genotype using the tomato root, the first tissue that interacts wi.. Read More»

Genet. Mol. Res. 16(2): gmr16027209

DOI: 10.4238/gmr16027209

Human Genetics   Research Article
Study on the association of UGT1A9 gene c.98T>C polymorphism and mycophenolic acid plasma levels in renal transplant patients

Authors: L.R. Ruschel, V.M. Schmitt, A.B. Silva, C.S.A. Oliveira, K. Flach, D.O. d�Avila and F.V. Thiesen

Mycophenolate mofetil (MMF) is a prodrug active only after its hydrolysis to mycophenolic acid (MPA). The UGT1A9 enzyme is of special interest since it is the main enzyme involved in the glucuronidation of MPA. Single nucleotide polymorphisms (SNPs) in the UGT1A9 gene may be responsible for individual differences in the pharma.. Read More»

Genet. Mol. Res. 16(2): gmr16029598

DOI: 10.4238/gmr16029598

Plant Genetics   Research Article
Minimum number of measurements for evaluating soursop (Annona muricata L.) yield

Authors: C.F.B. S�¡nchez, P.E. Teodoro, S. Londo�±o, L.A. Silva, L.A. Peixoto and L.L. Bhering

Repeatability studies on fruit species are of great importance to identify the minimum number of measurements necessary to accurately select superior genotypes. This study aimed to identify the most efficient method to estimate the repeatability coefficient (r) and predict the minimum number of measurements needed for a more a.. Read More»

Genet. Mol. Res. 16(2): gmr16029594

DOI: 10.4238/gmr16029594

Human Genetics   Research Article
Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population

Authors: V.R.Z.B. Pereira, J.M. Wolf, G.Z. Stumm, T.R. Boeira, J. Galvan, D. Simon and V.R. Lunge

Hepatitis B virus (HBV) infection is a serious public health problem worldwide. The progression of the disease depends on several host and viral factors and may result in fulminant hepatitis (very rare), acute hepatitis with spontaneous clearance, and chronic hepatitis B infection. Previous studies demonstrated that variations.. Read More»

Genet. Mol. Res. 16(2): gmr16029565

DOI: 10.4238/gmr16029565