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Human Genetics   Research Article
Phenotypic classification of gastric signet ring cell carcinoma and its relationship with K-ras mutation

Authors: Z.F. Xiong, J. Shi, Z.H. Fu, H.P. Wan and L.X. Tu

We aimed to analyze gastric signet ring cell (SRC) carcinoma subtypes by investigating gastric and intestinal phenotypic marker expression, and explore the relationship between phenotype and K-ras mutation. Immunohistochemistry was performed on 163 SRC carcinoma patient specimens to detect gastric (MUC1, MUC5AC, and MUC6) and .. Read More»

Genet. Mol. Res. 16(2): gmr16029181

DOI: 10.4238/gmr16029181

Human Genetics   Research Article
Polymorphism of the gene eNOS G894T (Glu298Asp) in symptomatic patients with aterosclerosis

Authors: F.L. Campedelli, K.S.F. e Silva, D.A. Rodrigues, J.V.M. Martins, I.R. Costa, M.H. Lagares, A.M. Barbosa, M.P. de Morais and K.K.V.O. Moura

Atherosclerotic and its cardiovascular complications are responsible for 17.5 million deaths a year, according to the World Health Organization. There is consensus that atherosclerosis involves multiple pathogenic processes initiated by endothelial dysfunction, with inflammation and vascular proliferation determining alteratio.. Read More»

Genet. Mol. Res. 16(2): gmr16029550

DOI: 10.4238/gmr16029550

Animal Genetics   Research Article
Hsp70 gene polymorphisms in farmed marine shrimp Litopenaeus vannamei populations exposed to white spot disease and infectious myonecrosis

Authors: A.L. Ferreira Jr, R. Maggioni, D. Concei�§�£o, L.M. Perazzolo and R.L. Petersen

Single nucleotide polymorphisms (SNPs) are the best genetic markers for associative studies of the immune system in invertebrates. In the marine shrimp Litopenaeus vannamei, SNPs linked to disease resistance have been reported for some genes, such as hemocyanin, anti-lipopolysaccharide factor, and heat-shock protein 70 (Hsp70).. Read More»

Genet. Mol. Res. 16(2): gmr16029668

DOI: 10.4238/gmr16029668

Plant Genetics   Research Article
Mendelian inheritance, genetic linkage, and genotypic disequilibrium for nine microsatellite loci in Cariniana estrellensis (Raddi) Kuntze (Lecythidaceae)

Authors: T.Y.K. Kubota, A.M. Silva, J. Cambuim, A.A. Silva, S. Pupin, M.S. Silva, M.A. Moraes, M.L.T. Moraes and A.M. Sebbenn

Cariniana estrellensis is one of the largest trees found in Brazilian tropical forests. The species is typical of advanced stages of succession, characteristic of climax forests, and essential in genetic conservation and environmental restoration plans. In this study, we assessed Mendelian inheritance, genetic linkage, and gen.. Read More»

Genet. Mol. Res. 16(2): gmr16029653

DOI: 10.4238/gmr16029653

Plant Genetics   Research Article
Contribution of morphoagronomic traits to grain yield and earliness in grain sorghum

Authors: K.J. da Silva, P.E. Teodoro, C.B. de Menezes, M.P.M. J�ºlio,V.F. de Souza, M.J. da Silva, L.D. Pimentel and A. Bor�©m

Given the importance of selecting lines to obtain hybrids, we aimed to verify the relationship between morphological traits that can be used as the criteria for the selection of sorghum lines with high grain yield and earliness. A total of 18 traits were evaluated in 160 sorghum elite lines, in an incomplete block design with .. Read More»

Genet. Mol. Res. 16(2): gmr16029649

DOI: 10.4238/gmr16029649

Plant Genetics   Research Article
DNA methylation in sugarcane somaclonal variants assessed through methylation-sensitive amplified polymorphism

Authors: J.H.M.B. Francischini, E.L. Kemper, J.B. Costa, J.R.V. Manechini and L.R. Pinto

Micropropagation is an important tool for large-scale multiplication of plant superior genotypes. However, somaclonal variation is one of the drawbacks of this process. Changes in DNA methylation have been widely reported as one of the main causes of somaclonal variations in plants. In order to investigate the occurrence of ch.. Read More»

Genet. Mol. Res. 16(2): gmr16029585

DOI: 10.4238/gmr16029585

Plant Genetics   Research Article
Genetic divergence among Psidium accessions based on single nucleotide polymorphisms developed for Eucalyptus

Authors: S.R. Costa and C.A.F. Santos

The goal of this study was to analyze the genetic divergence among Psidium species accessions based on SNPs developed for Eucalyptus. Fifty-three Psidium accessions, including 47 P. guajava, were genotyped with EUCHIP60K. The dendrogram similarity ranged from 0.58 to 1.00, with a cophenetic value of 0.97. Five groups were iden.. Read More»

Genet. Mol. Res. 16(2): gmr16029566

DOI: 10.4238/gmr16029566

Plant Genetics   Research Article
Analysis of genetic diversity of Leuciscus leuciscus baicalensis using novel microsatellite markers with cross-species transferability

Authors: D.J. Lei, G. Zhao, P. Xie, Y. Li, H. Yuan, M. Zou, J.G. Niu and X.F. Ma

We used next-generation sequencing technology to characterize 19 genomic simple sequence repeat (SSR) markers and 11 expressed sequence tag (EST) SSR markers from Leuciscus leuciscus baicalensis, a small freshwater fish that is widely distributed in Xinjiang, China. Primers were used to test for polymorphisms in three L. leuci.. Read More»

Genet. Mol. Res. 16(2): gmr16029376

DOI: 10.4238/gmr16029376