Animal Genetics
Effects of Shenkangling intervention on the MAPK pathway in rats with doxorubicin-induced nephropathy
Authors: S. Ai, Y.Y. Lin, J. Zheng, C.X. Qiu, Y.J. Liu and X. Lin
Shenkangling plays a role of Yishenhuoxue effect for the treatment of children with nephrotic syndrome. The aim of this study was to investigate the effects of Shenkangling intervention on the mitogen-activated protein kinase (MAPK) pathway in rats with Adriamycin-induced nephropathy (AN) and its underlying mechanism of action. Nephrosis was induced in he.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038131
- DOI:
- 10.4238/gmr.15038131
Estimation of genetic parameters and genetic changes for growth characteristics of Santa Ines sheep
Authors: E.L. Aguirre, E.C. Mattos, J.P. Eler, A.D. Barreto Neto and J.B. Ferraz
Studying genetic parameters and genetic changes in Santa Ines sheep is important, because it is the commonest breed in Brazil. This study obtained genetic data from 37,735 pedigree records of lambs over 12 years (2003-2014) from 33 flocks in 10 Brazilian States; 11,851 records of performance were available. (Co)variance components, genetic parameters and .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038910
- DOI:
- 10.4238/gmr.15038910
Association between a non-synonymous HSD17B4 single nucleotide polymorphism and meat-quality traits in Berkshire pigs
Authors: J.L. Jo, J.H. Hwang, S.G. Kwon, D.H. Park, T.W. Kim, D.G. Kang, G.E. Yu, I.S. Kim, J. Ha and C.W. Kim
Single nucleotide polymorphisms (SNPs) are useful genetic markers that allow correlation of genetic sequences with phenotypic traits. It is shown here that HSD17B4, a bifunctional enzyme mediating dehydrogenation and anhydration during β-oxidation of long-chain fatty acids, contains a non-synonymous SNP (nsSNP) of chr2:12.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048970
- DOI:
- 10.4238/gmr15048970
Histone H3K9 acetylation influences growth characteristics of goat adipose-derived stem cells in vitro
Authors: X. Wang, F.X. Zhang, Z.M. Wang, Q. Wang, H.F. Wang, Y. Ren,D.P. Tai, H. Liang and D.J. Liu
Adipose-derived stem cells (ADSCs) show nearly unlimited potential in medical and animal science. Currently, understanding of the biological mechanisms regulating ADSC growth in vitro remains very limited. Histone acetylation, an epigenetic modification, plays a key role in maintaining stem cell properties. To further study it.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048954
- DOI:
- 10.4238/gmr15048954
Wnt7b gene expression and functional analysis in the mussel Mytilus coruscus
Authors: Y.F. Xu, X. Liang, Y.R. Chen, Y.F. Li and J.L. Yang
To understand the potential functions of Wnt7b in different developmental stages and adult tissues of the mussel Mytilus coruscus, the Wnt7b gene was cloned using the rapid amplification of cDNA ends technique. The full-length Wnt7b gene was 1910 bp long, with a 1059-bp open reading frame encoding 352 amino acids. The amino ac.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048866
- DOI:
- 10.4238/gmr15048866
Development and characterization of microsatellite markers for Brazilian four-eyed frogs (genus Pleurodema) endemic to the Caatinga biome
Authors: M.T.C. Thom�©, J. Alexandrino, S. Lopes, C.F.B. Haddad and F. Sequeira
We used pyrosequencing to develop microsatellite markers for the Brazilian four-eyed frog Pleurodema diplolister and tested the microsatellite markers for cross-amplification in its sister Pleurodema alium, which are both endemic species of the Caatinga biome in northeastern Brazil. We used multiplex sets to amplify and genoty.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.12.12
- DOI:
- http://dx.doi.org/10.4238/2014.March.12.12
Limitations of cytochrome oxidase I for the barcoding of Neritidae (Mollusca: Gastropoda) as revealed by Bayesian analysis
Authors: S.Y. Chee
The mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) gene has been universally and successfully utilized as a barcoding gene, mainly because it can be amplified easily, applied across a wide range of taxa, and results can be obtained cheaply and quickly. However, in rare cases, the gene can fail to distinguish between species, particularly when expose.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.20
- DOI:
- 10.4238/2015.May.25.20
Isolation and characterization of polymorphic microsatellite markers in the endangered species Bretschneidera sinensis Hemsl.
Authors: M. Li, H.F. Chen, Z.F. Wang and S. Zhang
Bretschneidera sinensis is an endangered species that is mainly distributed in South China. As a tertiary relict and the single species in the Bretschneideraceae family, it has a high conservation value. To investigate the influence of human disturbance on its mating system, 63 new microsatellites were developed using restriction-site-associated DNA seque.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038234
- DOI:
- 10.4238/gmr.15038234
Genetic variation of bovine leukemia virus (BLV) after replication in cell culture and experimental animals
Authors: M.F. Camargos, D.S. Raj�£o, R.C. Leite, D. Stancek, M.B. Heinemann and J.K.P. Reis
This article reports the selection of bovine leukemia virus (BLV) variants after continuous passage in cell lines or experimental animals. Two wild BLV strains isolated from 2 naturally infected Holstein dairy cows in Brazil (cow codes: 485 and 141) were used for the experimental infection of 1 sheep and FLK cells, and 1 rabbi.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.22.11
- DOI:
- http://dx.doi.org/10.4238/2014.January.22.11
Differential expression of genes during mastitis in Holstein-Zebu crossbreed dairy cows
Authors: I. Fonseca, G.R. Antunes, D.S. Paiva, C.C. Lange, S.E.F. Guimar�£es and M.F. Martins
Among the potential public health problems of animal production, infectious-contagious diseases stand out. Mastitis is among the main diseases affecting dairy cattle. One of the most promising options to reduce the problems caused by this disease, besides proper sanitary and management practices, is selective breeding of resis.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1096
- DOI:
- 10.4238/vol10-3gmr1096