Animal Genetics

Leishmania (Viannia) braziliensis in dogs in Brazil: epidemiology, co-infection, and clinical aspects

Authors: F.S. Carvalho, A.A. Wenceslau, G.R. Albuquerque, A.D. Munhoz, E. Gross, P.L.S. Carneiro, H.C. Oliveira, J.M. Rocha, I.A. Santos and R.P. Rezende

Leishmaniasis is an endemic disease present in 98 countries. In Brazil, the northeast region accounts for approximately half of the cases in humans, and has experienced an increased number of positive cases in dogs. In this study, we investigated the epidemiology of canine leishmaniasis in the city of Ilhéus, Bahia, usi.. Read More»

Genet. Mol. Res. 14(4):

2015.October.5.19

DOI:

10.4238/2015.October.5.19

Case-control study and meta-analysis of Ser311Cys polymorphism in the DRD2 gene demonstrate lack of association with risk for schizophrenia in the Japanese population

Authors: Y. Watanabe, A. Nunokawa, N. Kaneko, M. Shibuya, J. Egawa, N. Fukui and T. Someya

Genet. Mol. Res. 11(2):

2012.April.27.13

DOI:

10.4238/2012.April.27.13

Assessment of correlation between pre-miRNA-1757 polymorphism and chicken performance traits

Authors: H. Li, K.R. Jiang, S.H. Wang, X.J. Liu, X.T. Kang, R.R. Jiang,Z.J. Li and G.R. Sun

Single nucleotide polymorphism in microRNAs (miRNA) may influence their target gene selection and regulation efficiency, leading to animal phenotypic variation. The aim of this study was to evaluate the possible effect of single nucleotide polymorphisms in the miRNA-1757 gene precursor region (pre-mir-1757) on economic-related.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.7

DOI:

10.4238/2015.October.9.7

DNA sequence variants in the carbonyl reductase 1 (cbr1) gene in seven breeds of Canis lupus familiaris

Authors: Q. Cheng, C. Sanborn, D. Ferguson and J.G. Blanco

The anticancer anthracyclines doxorubicin and daunorubicin are used to treat a variety of cancers in dogs. The therapeutic utility of anthracyclines is limited by cardiotoxicity in some cases. Synthesis of anthracycline alcohol metabolites by carbonyl reductase 1 (CBR1) is crucial for the pathogenesis of cardiotoxicity. We hyp.. Read More»

Genet. Mol. Res. 11(2):

2012.April.27.10

DOI:

10.4238/2012.April.27.10

Differences in H3K4 trimethylation in in vivo and in vitro fertilization mouse preimplantation embryos

Authors: F.-R. Wu, Y. Liu, M.-B. Shang, X.-X. Yang, B. Ding, J.-G. Gao, R. Wang and W.-Y. Li

Trimethylation of lysine 4 at histone 3 (H3K4me3) is considered a marker of active transcription; it plays an important role in transcription reprogramming efficiency. We compared the levels of H3K4me3 in mouse preimplantation embryos from MII stage oocytes produced by in vivo and in vitro fertilization (IVF) using immunofluor.. Read More»

Genet. Mol. Res. 11(2):

2012.April.27.9

DOI:

10.4238/2012.April.27.9

Single nucleotide polymorphisms of Ã?Â?6-desaturase and Elovl5 segments and their associations with common carp (Cyprinus carpio) growth traits

Authors: H. Ren, J. Yu, P. Xu and Y. Tang

Highly unsaturated fatty acids (HUFAs) are crucial for the nutritional health, physiology, and reproduction of vertebrates. The Δ6-desaturase and Elovl5 elongase genes produce essential enzymes in the biosynthetic pathway of HUFAs. Single nucleotide polymorphism (SNP) analysis of genes functionally related to the growth traits of the common carp (Cy.. Read More»

Genet. Mol. Res. 14(4):

2015.October.21.4

DOI:

10.4238/2015.October.21.4

Changes in cFLIP expression in the corpus luteum throughout the estrous cycle of Shibagoats

Authors: H.Z. Jin, Y. Wang, Y. Liu, X.P. Li and Y. Jin

Changes in the expression of the anti-apoptotic protein cFLIP (cellular FLICE inhibitory protein) were examined in the caprine corpus luteum (CL), during development and subsequent maintenance. Corpora lutea at four different stages were collected from Shiba goats, to measure the expression of cFLIP mRNA, protein and immunolocalization. Expression of shor.. Read More»

Genet. Mol. Res. 14(4):

2015.October.21.16

DOI:

10.4238/2015.October.21.16

Repairing rabbit radial defects by combining bone marrow stroma stem cells with bone scaffold material comprising a core-cladding structure

Authors: H. Wu, G.H. Liu, Q. Wu and B. Yu

We prepared a bone scaffold material comprising a PLGA/β-TCP core and a Type I collagen cladding, and recombined it with bone marrow stroma stem cells (BMSCs) to evaluate its potential for use in bone tissue engineering by in vivo and in vitro experiments. PLGA/β-TCP without a cladding was used for comparison. The ad.. Read More»

Genet. Mol. Res. 14(4):

2015.October.5.7

DOI:

10.4238/2015.October.5.7

Association of CRTC2 gene polymorphisms with growth and meat quality traits of Qinchuan cattle

Authors: H.C. Xu, L.S. Gui, N. Song, Y.Y. Zhang, H.C.Wang and L.S. Zan

Growth and meat quality traits play important roles in the evaluation of cattle productivity and are influenced by genetic and environmental factors. CRTC2 is a recently discovered gene related to obesity that may influence fat deposition. The aim of the current study was to detect polymorphisms of bovine CRTC2 and explore their relationships to growth an.. Read More»

Genet. Mol. Res. 14(4):

2015.October.21.12

DOI:

10.4238/2015.October.21.12

Genome-wide identification of copy number variations in Holstein cattle from Baja California, Mexico, using high-density SNP genotyping arrays

Authors: R. Salom�³n-Torres, V.M. Gonz�¡lez-Vizcarra, G.E. Medina-Basulto,M.F. Monta�±o-G�³mez, P. Mahadevan, V.H. Yaurima-Basald�ºa, C. Villa-Angulo1 and R.Villa-Angulo

Copy number variations (CNVs) are an important source of genomic structural variation, and can be used as markers to investigate phenotypic and economic traits. CNVs also have functional effects on gene expression and can contribute to disease susceptibility in mammals. Currently, single nucleotide polymorphism genotyping arra.. Read More»

Genet. Mol. Res. 14(4):

2015.October.2.18

DOI:

10.4238/2015.October.2.18