Animal Genetics
RAPD and barcode analyses of groupers of the genus Epinephelus
Authors: K. Noikotr1, A. Chaveerach1, K. Pinthong2, A. Tanomtong1, R. Sudmoon1 and T. Tanee3
The diversity of Epinephelus species was investigated throughout Thailand. Random amplified polymorphic DNA successfully produced 1300 bands that were phylogenetically informative and used to construct cladograms. Values of pairwise genetic similarity (S) within species ranged from 0.65 in E. erythrurus to 0.99 in E. malabaricus. The interspecific values .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.21
- DOI:
- 10.4238/2013.November.18.21
The role of Hsp90�± in heat-induced apoptosis and cell damage in primary myocardial cell cultures of neonatal rats
Authors: A. Islam, Y.J. Lv, A. Abdelnasir, B. Rehana, Z.J. Liu, M. Zhang S. Tang, Y.F. Cheng, H.B. Chen, J. Hartung, E.D. Bao
To understand the mechanism underlying the sudden animal death caused by acute heart failure during heat stress, the relationships among the heat-induced pathological changes and apoptosis and the variations in the levels of protective Hsp90α and its mRNA in the heat-stressed primary myocardial cells of neonatal rats in .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.6
- DOI:
- 10.4238/2013.December.2.6
Co-transfection of adeno-associated virus-mediated human vascular endothelial growth factor165 and transforming growth factor-�²1 into annulus fibrosus cells of rabbit degenerative intervertebral discs
Authors: Y.M. Xi, Y.F. Dong, Z.J. Wang, Y. Liu, Z.Z. Diao and Y.G. Hu
Intervertebral disc degeneration is a common condition that may lead to low back pain and radiculopathy. Understanding the pathophysiology and cellular and molecular events of degenerative disc disease has resulted in the proposal of a gene therapy approach to halt and reverse disc degeneration. We explored the feasibility of reversing intervertebral disc.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.11
- DOI:
- 10.4238/2013.February.28.11
Genetic diversity analysis of oriental river prawn, Macrobrachium nipponense, in Yellow River using microsatellite marker
Authors: H. Qiao1, D. Lv2, S.F. Jiang1, S.M. Sun1, Y.S. Gong1, Y.W. Xiong1, S.B. Jin1 and H.T. Fu1
To assess the genetic status of this species, the genetic diversity of wild Macrobrachium nipponense from seven geographic locations in the Yellow River basin were investigated using 20 polymorphic microsatellite DNA loci. The genetic diversity between populations was indicated by the mean number of alleles per locus and mean observed heterozygosity (H) a.. Read More»
- Genet. Mol. Res. 12(4):
Association between the Rs3087243 polymorphism and risk for diabetes: a meta-analysis
Authors: J. Liu and H.-X. Zhang
The aim of this study was to evaluate the association between the rs3087243 polymorphism of the cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene and the risk of type 1 diabetes mellitus (T1D). A comprehensive meta-analysis of case-control studies was conducted to determine the association between the rs3087243 polymorphism (CT60A/G) and T1D and a.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.6.1
- DOI:
- 10.4238/2013.December.6.1
Construction and characterization of a cDNA expression library from the endangered Hu sheep
Authors: P.-F. Hu1,2*, X.-C. Li1*, H.-K. Liu1, W.-J. Guan1 and Y.-H. Ma1
Hu sheep is one of the most important species in China; it is also listed as one of the 78 nationally protected domestic animals by the Chinese government in 2000. The construction of cDNA expression library of Hu sheep is of great significance for protecting individual genomes, generating transgenic sheep, and conducting clinical research using cDNA from.. Read More»
- Genet. Mol. Res. 13(4):
Myf5 gene polymorphisms and production performance traits in Songliao white geese
Authors: J.B. Wu, L.P. Cao, M.M. Li, N.N. Du, H.L. Huang and Y. Jin
To explore the relationship between Myf5 gene polymorphisms and production performance traits in Songliao white geese, we used the chicken Myf5 sequence to design primers and amplified part of the exon 1 sequence of the Songliao white goose Myf5 gene. Results of single-strand conformation polymorphism polymerase chain reaction.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.3
- DOI:
- 10.4238/2013.December.2.3
A novel synthetic Cry1Ab gene resists rice insect pests
Authors: F.S. Song, D.H. Ni, H. Li, Y.B. Duan, Y.C. Yang, J.L. Ni, X.Z. Lu, P.C. Wei, L. Li and J.B. Yang
A few insect control genes of Bacillus thuringiensis have been modified successfully to increase the expression in plants by replacing rare codons, increasing GC content, and avoiding the DNA elements that could cause premature transcription termination, mRNA instability, and potential methylation. However, th.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.12
- DOI:
- 10.4238/2014.April.3.12
Kin structure and parallel dispersal in the black-and-gold howler monkey Alouatta caraya (Platyrrhini, Atelidae)
Authors: R.G. Collevatti, A.C. Souza-Neto, N.J. Silva-Jr, M.P.C. Telles
We here investigated the kin structure and pattern of dispersal in the black-and-gold howler monkey (Alouatta caraya, Platyrrhini, Atelidae) based on genotype differences at nine microsatellite loci of 48 individuals from eight social groups along the riparian forest of the Tocantins River, Brazil. The genetic diversity (HE = .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.27.1
- DOI:
- 10.4238/2013.November.27.1
Effect of ERCC1 polymorphism on the response to chemotherapy and clinical outcome of non-small cell lung cancer..
Authors: H. Gao1, R.C. Ge2, H.Y. Liu3, Y. Wang4 and S. Yan4....
We conducted a cohort study to investigate the role of 3 single-nucleotide polymorphisms of the excision repair cross-complementation group 1 (ERCC1) gene on the response to chemotherapy and clinical outcomes of non-small cell lung cancer (NSCLC). A total of 163 patients with newly diagnosed and histopathologically confirmed primary NSCLC were examined in.. Read More»
- Genet. Mol. Res. 13(4):