Warfarin
Pharmacogenetics-based warfarin dose prediction algorithm for patients with heart valve replacement in Southeast China
Authors: M.Q. Lin, J. Zhang, H.F. Qiu, X.B. Xie and H.T. Song
This study was designed to analyze the influence of polymorphisms in CYP2C9, VKORC1, CYP4F2, GGCX, and EPHX1 genes on the optimal warfarin dosage in patients who have undergone artificial heart valve replacement and establish an algorithm for use by physicians in Southeast China to predict each patient’s optimal steady-s.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16038881
- DOI:
- 10.4238/gmr16038881
Pharmacogenomics: accessing important alleles by imputation from commercial genome-wide SNP arrays
Authors: R. Liboredo and S.D.J. Pena
Personalized medicine is becoming a medical reality, as important genotype-phenotype relationships are being unraveled. The availability of pharmacogenomic data is a key element of individualized care. In this study, we explored genotype imputation as a means to infer important pharmacogenomic alleles from a regular commercial.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.27
- DOI:
- 10.4238/2014.July.25.27