Vitiligo
IGF2BP2 gene polymorphism in the pathogenesis of vitiligo
Authors: Kursat Kargun, Betul Demir, Demet Cicek, Ozge Sevil Karstarli
Vitiligo is a disorder of pigmentation presenting with loss of melanocytes in the epidermis and hair follicles. The gene for insulin-like growth factor binding protein 2 (IGF2BP2) is located on the third chromosome and it plays role in growth, development, cellular differentiation, and metabolism. In the present study, we aime.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039808
- DOI:
- 10.4238/gmr16039808
Detection of serum anti-melanocyte antibodies and identification of related antigens in patients with vitiligo
Authors: M.C. Zhu,C.G. Liu, D.X. Wang,Z. Zhan
We detected autoantibodies against melanocytes in serum samples obtained from 50 patients, including 4 with HBV, with vitiligo and identified the associated membrane antigens. Heat shock protein 70 (HSP70) and anti-tyrosinase-related protein 1 (TRP-1) antibody levels were analyzed. The associated antigens in normal human melan.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.19
- DOI:
- 10.4238/2015.December.7.19
Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population
Authors: H. Bulut, M. Pehlivan, S. Alper, A.G. Tomatir, H. Onay, S.E. Y�¼ksel, F. ��zkinay and S. Pehlivan
Accumulation of hydrogen peroxide (H2O2) and low catalase (CAT) activity have been demonstrated in the epidermis of vitiligo patients. We investigated a possible association between the CAT exon 9 (Asp-389) gene and vitiligo susceptibility in the Turkish population. Thirty-four patients with vitiligo and 49 gender, age and eth.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.13
- DOI:
- 10.4238/2011.October.31.13
Associations between TNF-�± polymorphisms and susceptibility to rheumatoid arthritis and vitiligo: a meta-analysis
Authors: Y.H. Lee and S.C. Bae
We investigated whether the tumor necrosis factor-a (TNF-α) promoter -238 A/G and -308 A/G polymorphisms are associated with rheumatoid arthritis (RA) and vitiligo susceptibility. MEDLINE and EMBASE databases and a manual search were used to identify articles in which TNF-α polymorphisms were determined in RA or vitiligo patients and controls... Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.6
- DOI:
- 10.4238/2015.May.25.6
Tumor necrosis factor-�± and -�² genetic polymorphisms as a risk factor in Saudi patients with vitiligo
Authors: F. Al-Harthi, A. Zouman, M. Arfin, M. Tariq and A. Al-Asmari
Vitiligo is an acquired depigmentary disorder of the skin, characterized by multiple susceptibility loci and genetic heterogeneity. The etiology of vitiligo is unknown but several hypotheses, including an autoimmune origin, have been proposed. Tumor necrosis factor (TNF)-α, a pleiotropic proinflammatory cytokine, has been shown to play a critical ro.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.8.1
- DOI:
- 10.4238/2013.July.8.1
Meta-analysis of the TNF-�±-308G/A polymorphism and vitiligo risk
Authors: G. Nie, J.H. Qi, C.W. Huang, T. Yang, N. Shi and Y.J. Chen
Several case-control studies have been conducted to investigate the association between the tumor necrosis factor-α (TNF-α)-308G/A polymorphism and vitiligo risk. However, the results of these studies are inconsistent; therefore, we attempted to comprehensively evaluate the association between TNF-α-308G/A polymorphism and vitiligo risk .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.30
- DOI:
- 10.4238/2015.December.16.30