Mesangial Cell
Effect of 1,25(OH)2D3 on the proliferation of human mesangial cells and their expression of Ki67
Authors: D. Zhao, C.-J. Zhang, R. Yang, J.-P. Chen, L. Ma, G. Liu and X.-P. Yang
Previous studies have found that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3 or VD3] exerts many biological effects, including the inhibition of cell proliferation and induction of apoptosis, but its mechanism of action remains unclear. The goal of our investigation was to explore the effects of 1,25(OH)2D3 on the proliferation of c.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029191
- DOI:
- 10.4238/gmr16029191
Effects of mycophenolate mofetil on the expression of monocyte chemoattractant protein-1 and fibronectin in high glucose cultured human mesangial cells
Authors: F.Q. Chen, Q.Y. Wang, G.Z. Wei, X.Y. Ma, D.W. Ma, W.W. Deng and W.B. Sun
The effects of high glucose on the expression of monocyte chemoattractant protein-1 (MCP-1) and the main component of the extracellular matrix, fibronectin (FN), were explored in human mesangial cells (HMCs), along with the intervention effects of mycophenolate mofetil (MMF) on these indicators. Cultured HMCs were divided into.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.11
- DOI:
- 10.4238/2014.April.17.11
Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion
Authors: C.Y. Liu, L.L. Zhou, Q. Cheng, S.N. Jiang, J. Sheng, J.D. Sun and J.Y. Zhao
Recent studies have found that bradykinin (BK) plays a role in delaying glomerulosclerosis, although the mechanism of this phenomenon remains unclear. Mesangial cell proliferation (MCP) and extracellular matrix (ECM) secretion are important mechanisms for glomerulosclerosis. This study investigated the impact of BK on the plat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.18
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.18