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Plant Genetics   Research Article

Complete sequence analysis of mitochondrial DNA of aplastic anemia patients

Authors: X. Cui, F. Liu, J.Q. Wang, W.J. Zhang, J.Y. Wang, K. Liu, S.Y. Cui, J. Zhang and R.R. Xu

This study was primarily undertaken to test the hypothesis that mitochondrial DNA (mtDNA) mutations may be associated with aplastic anemia (AA). We analyzed mtDNA sequences from 15 patients with AA. The samples were obtained from bone marrow, and patients’ oral epithelial cells were collected for normal tissue comparison. Total DNA was amplified by .. Read More»

Genet. Mol. Res. 11(3):
Plant Genetics   Research Article

Genetic variability among the chloroplast genomes of sugarcane (Saccharum spp) and its wild progenitor species Saccharum spontaneum L.

Authors: J.-R. Zhu, H. Zhou, Y.-B. Pan and X. Lu

A striking characteristic of modern sugarcane is that all sugarcane cultivars (Saccharum spp) share a common cytoplasm from S. officinarum. To explore the potential value of S. spontaneum cytoplasm, new Saccharum hybrids with an S. spontaneum cytoplasm were developed at the United States Department of Agriculture-Agricultural .. Read More»

Genet. Mol. Res. 13(2):
Microbial Genetics   Research Article

Arm-Gal4 inheritance influences development and lifespan in Drosophila melanogaster

Authors: F.A. Slade and B.E. Staveley

The UAS-Gal4 ectopic expression system is a widely used and highly valued tool that allows specific gene expression in Drosophila melanogaster. Yeast transcription factor Gal4 can be directed using D. melanogaster transcriptional control elements, and is often assumed to have little effect on the organism. By evaluation of the.. Read More»

Genet. Mol. Res. 14(4):
Human Genetics   Research Article

Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes

Authors: F.M. Amaral, A.L. Miranda-Vilela, G.S. Lordelo, I.F. Ribeiro, M.B. Daldegan and C.K. Grisolia

High plasma homocysteine (Hcy) ​​levels may be responsible for vaso-occlusive episodes and may have acquired and/or genetic causes. This cross-sectional study aimed to investigate the role of methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C) and cystathionine-β-synthase (CBS; T833C/844ins68, G919A) polymorphi.. Read More»

Genet. Mol. Res. 16(1):
Plant Genetics   Research Article

Genetic analysis and identification of SSR markers associated with rice blast disease in a BC2F1 backcross population

Authors: N. Hasan, M.Y. Rafii, H. Abdul Rahim, S.A. Nusaibah, N. Mazlan and S. Abdullah

Rice (Oryza sativa L.) blast disease is one of the most destructive rice diseases in the world. The fungal pathogen, Magnaporthe oryzae, is the causal agent of rice blast disease. Development of resistant cultivars is the most preferred method to achieve sustainable rice production. However, the effectiveness of resistant cult.. Read More»

Genet. Mol. Res. 16(1):
Human Genetics   Research Article

Construction of polycythemia vera protein interaction network and prediction of related biological functions

Authors: L.-J. Liu1, X.-J. Cao2, C. Zhou1, Y. Sun3, Q.-L. Lv3, F.-B. Feng1, Y.-Y. Zhang4 and C.-G. Sun1

Here, polycythemia vera (PV)-related genes were screened by the Online Mendelian Inheritance in Man (OMIM), and literature pertaining to the identified genes was extracted and a protein-protein interaction network was constructed using various Cytoscape plugins. Various molecular complexes were detected using the Clustervize plugin and a gene ontology-enr.. Read More»

Genet. Mol. Res. 15(1):
Human Genetics   Research Article

Characterization of mitochondrial genotypes in the foundation herd of the Canchim beef cattle breed

Authors: S.C. Méo C.R. Ferreira M.R. Chiaratti F.V. Meirelles L.C.A. Regitano M.M. Alencar P.F. Barbosa

The Canchim (5/8 Charolais + 3/8 Zebu) beef cattle breed was developed at Southeast-Embrapa Cattle to take advantage of hybrid vigor and to combine the higher growth rate and beef quality of Charolais with tropical adaptations of Zebu. The development of three lineages (old, new, and crossbred) has increased its genetic basis... Read More»

Genet. Mol. Res. 8(1):
Medical Genetics   Research Article

Recent progress in identification and characterization of loci associated with sex-linked congenital cataract

Authors: D.D. Zhang, J.Z. Du, J. Topolewski and X.M. Wang

Congenital cataract is a common cause of blindness in children; however, its pathogenesis remains unclear. Genetic factors have been shown to play an important role in the pathogenesis of congenital cataract. The current genetic models of congenital cataract include autosomal dominant, autosomal recessive, and sex-linked inheritance. Sex-linked congenital.. Read More»

Genet. Mol. Res. 15(3):
Plant Genetics   Research Article

Soybean rust resistance sources and inheritance in the common bean (Phaseolus vulgaris L.)

Authors: T.L.P.O. Souza, S.N. Dessaune, M.A. Moreira and E.G. Barros

Soybean rust (SBR), caused by the fungus Phakopsora pachyrhizi, has been reported in common bean (Phaseolus vulgaris L.) cultivars and elite lines that were infected under controlled and natural field conditions in South Africa, the United States, Argentina, and Brazil. Although SBR is currently not a top pri.. Read More»

Genet. Mol. Res. 13(3):
Plant Genetics   Research Article

Combining ability of tropical and temperate inbred lines of popcorn

Authors: V.Q.R. da Silva, A.T. do Amaral Júnior, L.S.A. Gonçalves, S.P. Freitas Júnior, L.S. Candido, C. Vittorazzi, L.M. Moterle, R.A. Vieira and C.A. Scapim

In Brazil, using combining ability of popcorn genotypes to achieve superior hybrids has been unsuccessful because the local genotypes are all members of the same heterotic group. To overcome this constraint, 10 lines (P1 to P10) with different adaptations to tropical or temperate edaphoclimatic environments were used to obtain.. Read More»

Genet. Mol. Res. 9(3):


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