Human Papillomavirus
Synergic effect of oral contraceptives, GSTP1 polymorphisms, and high-risk HPV infection in development of cervical lesions
Authors: B.S. Chagas, A.P.A.D. Gurgel, S.S.L. Paiva J?ºnior, R.C.P. Lima,M.N. Cordeiro, R.R. Moura, A.V.C. Coelho, K.C.G. Nascimento,J.C. Silva Neto, S. Crovella and A.C. Freitas
Human papillomavirus (HPV) infection is considered a risk factor for cervical cancer. Even if the high-risk HPV (HR-HPV) infection is necessary, environmental co-factors and genetic susceptibility also play an important role in cervical cancer development. In this study, a possible association of rs1695 GSTP1 polymorphisms, HR.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039742
- DOI:
- 10.4238/gmr16039742
Comparison of the prevalence and distribution of human papillomavirus infection and cervical lesions between urban and native habitants of an Amazonian region of Peru
Authors: M. Martorell, J.A. Garcia-Garcia, D. Gomez-Cabrero, A. del Aguila
We made a study of the prevalence of human papillomavirus (HPV) and cervix lesions in an Amazonian Bora native population (Bn) and compared it with the prevalence in an urban population in Iquitos (Iq). We also examined the distribution of HPV types among abnormal cervical smears in the Iq population. Swabs and cytologies were collected from 472 females. .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.6.14
- DOI:
- 10.4238/2012.August.6.14
HPV31 and HPV33 incidence in cervical samples from women in Recife, Brazil
Authors: M.F.P.T. Baldez da Silva, B.S. Chagas, V. Guimar?£es, L.M.C. Katz,P.M. Felix, P.M. Miranda, A.A. Lima, L.C. Arraes, D.B.G. Martins, J.L. Lima Filho, R.C. Stocco, S. Crovella,7, A.C. Freitas and W. Be?§ak
Human papillomavirus (HPV) has been extensively studied concerning genomic structure, infection mechanisms, and diversity of types, as well as disease progression stages and development of vaccines. HPV type prevalence can differ in specific populations in different countries, according to ethnicity. This is the first report o.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr677
- DOI:
- 10.4238/vol8-4gmr677
Immunoexpression of HPV 16/18 E6 and E7 oncoproteins in high-grade cervical squamous intraepithelial lesions in HIV-positive women
Authors: L.C. Rodrigues1, N.M. de Gois Speck1, G.R. de Azevedo Focchi2, M.A. Schimidt1, R.M. Marques3 and J.C. Lascasas Ribalta1
The aim of this study was to assess the immunoexpression of human papillomavirus genotypes 16 and 18 (E6 and E7) oncoproteins in cervical high-grade squamous intraepithelial lesions (HSIL) of human immunodeficiency virus (HIV)-positive women. These results were also compared to the persistence and/or recurrence of lesions after loop electrosurgical excisi.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017220
- DOI:
- 10.4238/gmr.15017220
Prevalence of human papillomavirus, Chlamydia trachomatis, and Trichomonas vaginalis infections in Amazonian women with normal and abnormal cytology
Authors: E. Costa-Lira, A.H.V.L. Jacinto, L.M. Silva, P.F.R. Napole?£o,R.A.A. Barbosa-Filho, G.J.S. Cruz, S. Astolfi-Filho and C.M. Borborema-Santos
Sexually transmitted infections are an important cause of morbidity among sexually active women worldwide, and have been implicated as cofactors in the pathogenesis of cervical cancer. We investigated the prevalence of human papillomavirus (HPV), Chlamydia trachomatis (CT), and Trichomonas vaginalis (TV), and accessed the dive.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029626
- DOI:
- 10.4238/gmr16029626
HPV genotyping and p16 expression in Xingu Indigenous Park, Brazil
Authors: V.G. Freitas, G.R. Focchi, E.R. Pereira, J.E. Levi, N.M.G. Speck and J.C. Ribalta
The association between high-risk human papillomavirus (HPV) genotypes and p16 expression in indigenous women from the Xingu Indigenous Park, Brazil, was unknown. This study evaluated p16 expression in women with a histological diagnosis of cervical intraepithelial neoplasia (CIN) 3 or higher and correlated this expression with HPV genotypes to determine .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15036840
- DOI:
- 10.4238/gmr.15036840
Prevalence and genotype distribution of human papillomavirus in women in the Henan Province
Authors: Y.-F. Zhi, X.-X. Cha, X.-F. Li, C. Qiu and S.-H. Rong
We studied human papillomavirus (HPV) prevalence and genotype distribution among women in the Henan Province to provide epidemiological data as a means of preventing cervical cancer and developing a vaccine. A total of 14,873 samples were genotyped by using polymerase chain reaction reverse dot-blot. The overall HPVpositive rate in the sample was 23.98% (.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.15
- DOI:
- 10.4238/2015.May.22.15
Characterization of gene methylation in human papillomavirus associated-head and neck squamous cell carcinoma
Authors: H.Z. Zhang, C.G. Shan, A.P. Huang and J.M. Wang
Head and neck squamous cell carcinoma (HNSCC) has become one of the most common forms of cancer worldwide. Hypermethylation-induced silencing of tumor-associated gene has been proposed as an important cofactor in cancer pathology. This paper aimed to characterize the gene methylation patterns in human papillomavirus (HPV) associated-HNSCC. TIMP3 and APC m.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038206
- DOI:
- 10.4238/gmr.15038206
Human papillomavirus infection in Brazilian women with normal cervical cytology
Authors: P.M. Miranda, B.C.V. Pitol, M.S. Moran, N.N.T. Silva, P.M. Felix, J.L. Lima-Filho, C.M. Carneiro, I.D.C.G. Silva, R.F. Carvalho, A.A. Lima, W. Be?§ak and R.C. Stocco
We examined the prevalence of human papillomavirus (HPV) infection in a sample of Brazilian women presenting normal cervical cytology. Possible interactions between patient characteristics and HPV infection were analyzed in order to provide background data to improve cervical cancer screening and prophylaxis. Cervical samples .. Read More»
- Genet. Mol. Res. 11(2):
- http://dx.doi.org/2012.June.29.8
- DOI:
- http://dx.doi.org/10.4238/2012.June.29.8
Human papillomavirus viral load in cervical intraepithelial neoplasia as a prognostic factor in a Mexican population
Authors: A.E. Bencomo-?lvarez, I. Limones-Perches, A.E. Su?¡rez-Rinc?³n, L.J. Ram?rez-Jirano, E. Borrayo-Carbajal, J. S?¡nchez-Corona and H. Montoya-Fuentes
Persistent infection with human papillomavirus (HPV) has been recognized as the main etiological factor of morbimortality in cervical cancer. Several factors have been associated with the development of cervical disease, but viral load has recently been proposed as an indicator of cervical neoplasia. Therefore, a single measur.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.2
- DOI:
- 10.4238/2012.October.4.2