Gstt1
Contribution of the GSTP1 gene polymorphism to the development of osteosarcoma in a Chinese population
Authors: W.R. Qu, J. Wu and R. Li
We conducted a case-control study to investigate the associations between GSTT1, GSTM1, and GSTP1 gene polymorphisms and development of osteosarcoma in a Chinese population. Between January 2013 and February 2015, 153 patients diagnosed with osteosarcoma and 252 control subjects were enrolled in the current study from the Orthopedic Hospital of the Second.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038034
- DOI:
- 10.4238/gmr.15038034
Analysis of the prevalence of polymorphisms in the glutathione S transferase gene (GST) in cataract patients from Goi�¢nia
Authors: I.R. Costa, R.S. Mascarenhas, J.F. Corr�ªa, F.R.B. Oliveira, S.G. Fernandes, F.O. Souza, G.M. dos Reis, A. de P.R. J�ºnior, D.A. Rodrigues, J.V.M. Martins, K.S.F. e Silva and K.K.V.O. Moura
The aim of this study was to determine the prevalence of polymorphisms in the glutathione S-transferase genes GSTM1 and GSTT1 in patients with lens opacity (cataract). Peripheral blood samples were obtained from male and female patients (N = 23) with cataract. The GSTM1 and GSTT1 polymorphic regions were amplified by polymerase chain reaction, and the amp.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038050
- DOI:
- 10.4238/gmr.15038050
Pterygium in patients from Goi�¢nia, Goi�¡s, Brazi
Authors: G.M. dos Reis, A. de P.R. J�ºnior, K.S.F. e Silva, D.A. Rodrigues,M.C.S. Gomes, J.V.M. Martins, I.R. da Costa, G.A. Freitas andK.K.O. Moura
Pterygium is an inflammatory and degenerative ocular surface disease in which the conjunctiva on the cornea grows to form a fibrous tissue in the shape of a triangle. The disorder may be characterized by cell proliferation, inflammatory processes, fibrosis, angiogenesis, and destruction of the extracellular matrix. The anomaly is considered a degenerative.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.4
- DOI:
- 10.4238/2015.June.9.4
Association between CYP19A1, GSTM1, GSTT1, and GSTP1 genetic polymorphisms and the development of endometriosis in a Chinese population
Authors: Y. Tuo, J.Y. He, W.J. Yan and J. Yang
Endometriosis is a common, complicated, and highly heterogeneous endocrine disease. Many genetic factors could affect the development of endometriosis. We performed a case-control study to evaluate the association between polymorphisms in CYP19A1 rs2899470, GSTM1, GSTT1, and GSTP1 rs1695 and the development of endometriosis in.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048837
- DOI:
- 10.4238/gmr15048837
GSTM1 and GSTT1 polymorphisms in endometriosis in women from Goi�¡s, Brazil
Authors: A.B. Frare, A.M. Barbosa, I.R. Costa, S.R. Souza, R.C.P.C. Silva, B.M. Bordin, C.L. Ribeiro J�ºnior and K.K.V.O. Moura
Endometriosis is a gynecologic pathology with a high prevalence and unknown etiology. Therefore, an increasing number of studies has been undertaken to search for associations between endometriosis and alterations or polymorphisms in candidate genes, including glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1). We analyze.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.2.1
- DOI:
- 10.4238/2013.August.2.1
Association of glutathione S-transferase (GST) genetic polymorphisms with treatment outcome of cisplatin-based chemotherapy for advanced non-small cell lung cancer in a Chinese population
Authors: H.L. Xiao, Z.T. Yang, F. Han and H.X. Wei
The aim of this study was to evaluate the association of GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms with the chemotherapy response and overall survival of advanced NSCLC. Two hundred and sixty-two patients with histologically confirmed advanced NSCLC (inoperable TNM stages IIIA, IIIB, and IV) wer.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027320
- DOI:
- 10.4238/gmr.15027320
Genetic polymorphisms in patients with endometriosis: an analytical study in Goi�¢nia (Central West of Brazil)
Authors: K.S.F. Silva and K.K.V.O. Moura
In healthy women, intra- and extracellular controls prevent the attachment and proliferation of ectopic endometrial cells. During endometriosis, abnormalities in these control mechanisms permit the survival of endometrial cells, their subsequent attachment to the peritoneal cavity, and disease progression. These abnormal cells.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028135
- DOI:
- 10.4238/gmr.15028135
Effect of GSTM1, GSTT1, and GSTP1 IIe105Val polymorphisms on susceptiblity to gestational diabetes mellitus
Authors: Y.H. Qiu, Y.L. Xu and W.H. Zhang
We investigate the role of the GSTM1, GSTT1, and GSTP1 IIe105Val genetic polymorphisms in the susceptibility to gestational diabetes mellitus. A total of 223 pregnant women with gestational diabetes mellitus and 265 healthy pregnant women were examined at The Second Affiliated Hospital of Shaanxi University of Chinese Medicine.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027711
- DOI:
- 10.4238/gmr.15027711
Glutathione S-transferase polymorphisms in varicocele patients: a meta-analysis
Authors: B. Zhu, L. Yin and J.Y. Zhang
The glutathione S-transferase (GST) family represents a major group of detoxification and antioxidant enzymes. Studies have shown that high oxidative stress levels are associated with varicocele. The objective of this study was to assess the relationship between GSTM1 and GSTT1 null polymorphisms and varicocele using a study group of 497 varicocele patien.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.34
- DOI:
- 10.4238/2015.December.28.34