Gene
Association of chicken growth hormone polymorphisms with egg production
Authors: Y.J. Su, J.T. Shu, M. Zhang, X.Y. Zhang, Y.J. Shan, G.H. Li, J.M. Yin, W.T. Song, H.F. Li and G.P. Zhao
Growth hormone (GH) has diverse functions in animals, together with other hormones from the somatotropic axis. Here, chicken GH (cGH) was investigated in recessive white chickens and Qingyuan partridge chickens as a candidate gene affecting egg production traits. Chicken egg production traits were studied in association with 4.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.3
- DOI:
- 10.4238/2014.July.4.3
Correlation between polymorphisms in the estrogen receptor �± gene and coronary heart disease: A meta-analysis
Authors: W. Zhou, K.H. He and M.H. Chen
The aim of this study was to conduct a systematic evaluation the correlation between polymorphisms in the estrogen receptor α gene (ESRα) and coronary heart disease susceptibility. Case-control studies until August 2015 analyzing the correlation between the ESRα PvuII T/C polymorphism and coronary heart disease were obtained from various.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037835
- DOI:
- 10.4238/gmr.15037835
Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays
Authors: Y.D. Apalasamy , F.M. Moy, S. Rampal, A. Bulgiba and Z. Mohamed
A genome-wide association study showed that the tagging single nucleotide polymorphism (SNP) rs7566605 in the insulin-induced gene 2 (INSIG2) was associated with obesity. Attempts to replicate this result in different populations have produced inconsistent findings. We aimed to study the association between the rs7566.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.4
- DOI:
- 10.4238/2014.July.4.4
Two genetic stocks of Steindachneridion melanodermatum living in sympatry in nature and genetic variability of wild parents and F1 generation
Authors: D.A. Matoso, M. da Silva, M.C.S. Cortinhas, M.M. Cestari, M.C. de Almeida, M.R. Vicari and R.F. Artoni
Steindachneridion melanodermatum is a large Brazilian catfish, highly prized for sport fishing and for its meat. Specimens of this species, both caught in nature from Iguacu River and F1 fish born in captivity, were analyzed with regard to patterns of RAPD molecular markers. Genetic similarity ranged from 0.57 to 0.95; two gro.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.8
- DOI:
- 10.4238/2011.October.25.8
Bone morphogenetic protein 9 facilitates osteocarcinoma cell apoptosis and inhibits in vivo tumor growth
Authors: J. Zhang, J.H. Liang and J.G. Huang
Osteosarcoma (OS) causes millions of death worldwide and, since there is no effective therapy, it is necessary to identify the molecular mechanism of OS, which can direct the development of new therapies. This study investigated the role of bone morphogenetic protein 9 (BMP9), a member of the transforming growth factor (TGF)-β family, in OS developme.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038036
- DOI:
- 10.4238/gmr.15038036
Clinical study of the correlation between complement factor H polymorphism and age-related macular degeneration
Authors: H.T. Dong, J.X. Zhang, Q.M. Li and F.Z. Li
This study aimed to investigate the correlation between age-related macular degeneration (AMD) of the liver-kidney yin-deficiency type and complement factor H (CFH) polymorphism, and to determine whether the C allele of the T1277C (Y402H) variant is a risk factor for this condition. We performed a case-control investigation of 60 patients with liver-kidne.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038457
- DOI:
- 10.4238/gmr.15038457
Cytochrome c oxidase subunit I barcoding of the green bee-eater (Merops orientalis)
Authors: I.A. Arif, H.A. Khan, M. Shobrak and J. Williams
DNA barcoding using mitochondrial cytochrome c oxidase subunit I (COI) is regarded as a standard method for species identification. Recent reports have also shown extended applications of COI gene analysis in phylogeny and molecular diversity studies. The bee-eaters are a group of near passerine birds in the family Meropidae. .. Read More»
- Genet. Mol. Res. 10(4):
Effect of pregnane X receptor polymorphisms on tacrolimus blood concentrations and the resulting adverse reactions in kidney transplantation recipients
Authors: Z.P. Wang, M. Zhao, Q.S. Qu and S.Z. Miao
We investigated the effect of pregnane X receptor (PXR) polymorphisms on tacrolimus (FK506) blood trough concentrations and the associated adverse reactions in kidney transplantation recipients (KTRs). Polymerase chain reaction (PCR)-restriction fragment length polymorphism was used to detect the genotypes of single nucleotide polymorphism loci in 336 KTR.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038464
- DOI:
- 10.4238/gmr.15038464
Sexing single bovine blastomeres using TSPY gene amplification
Authors: M.C.A. Carneiro, P.L. Takeuchi, A. Ara�ºjo, R.B. L�´bo, F.P. Elias, R.A. Vila, C.L. Miranda-Furtado and E.S. Ramos
The testis-specific protein Y-encoded gene (TSPY) is a Y-specific gene present in variable copy number in many mammalian species, including cattle. We tested the applicability of the TSPY gene as a Y-specific marker to predict preimplantation embryo sex in Nelore (Bos indicus) cattle. Two blastomeres were removed from each emb.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.1
- DOI:
- 10.4238/2011.October.25.1
Isolation and characterization of microsatellite loci in Sisyrinchium (Iridaceae) and cross amplification in other genera
Authors: R.B. Miz, L.O. Tacuati�¡, F.W. Cidade, A.P. de Souza, F. Bered, L. Eggers and T.T. de Souza-Chies
Recent phylogenetic studies on Sisyrinchium strongly suggest that species classified in section Hydastylus and section Viperella belong to a single group of plants in recent adaptive radiation (Clade IV). These species neither present clear morphological differentiation among them nor show clear identification using DNA barcode markers. Thus, the main goa.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038474
- DOI:
- 10.4238/gmr.15038474