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Gene

Animal Genetics   Research Article

B chromosome prevalence and physical mapping of 18S rDNA and H4 histone sites in the grasshopper Xyleus discoideus angulatus (Romaleidae)

Authors: C.B. Machado, L.C. Silva Neto, V. Loreto and M.J. Souza

We sampled 11 natural populations of the grasshopper Xyleus discoideus angulatus in Northeastern Brazil to analyze B chromosome frequency and meiotic behavior. We observed a single large B chromosome, resembling the X chromosome, in 29 of the 402 specimens. Eight of the 11 populations had B chromosomes, with a rather .. Read More»

Genet. Mol. Res. 13(3):
2014.March.26.4
DOI:
10.4238/2014.March.26.4
Human Genetics   Research Article

Repair of cartilage defects in BMSCs via CDMP1 gene transfection

Authors: G. Wu, Y. Cui, Y.T. Wang, M. Yao, J. Hu, J.X. Li, Y. Wang andB. Zhang

This study aimed at investigating the ability of cartilage-derived morphogenetic protein 1 (CDMP1) gene-transfected bone marrow mesenchymal stem cells (BMSCs) loaded on the poly(lactic-co-glycolic acid) (PLGA) scaffold for the repair of laryngeal cartilage defects and make a preliminary assessment of its repair effect. The mRN.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.14
DOI:
10.4238/2014.January.17.14
Medical Genetics   Research Article

Toll-like receptor 3 polymorphism is not associated with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in the Chinese

Authors: Y. Cheng, M.W. Li, H.P. Li, W.T. Zeng, P. Zhou, L.Z. Huang, X.X. Li and Y.Y. Sun

Toll-like receptor 3 (TLR3) variants in mainland northern Chinese patients with polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (nAMD) were investigated. The complete genes of TLR3, including all exons and the promoter region, were assessed using direct sequencing technology of 284 unre.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.15
DOI:
10.4238/2014.January.17.15
Plant Genetics   Research Article

Genetic diversity in sugarcane varieties in Brazil based on the Ward-Modified Location Model clustering strategy

Authors: B.P. Brasileiro, C.D. Marinho, P.M.A. Costa, E.F.A. Moreira, L.A. Peternelli and M.H.P. Barbosa

We evaluated the genetic diversity of 77 clones of sugarcane used in crosses made by the Brazilian interuniversity network for the development of the sugar/energy sector (RIDESA) breeding program. Characterization of the genotypes was carried out at the ratoon stage, based on eight morphological traits and seven agronomic trai.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.2
DOI:
10.4238/2014.January.17.2
Plant Genetics   Research Article

Morphology and photosynthetic enzyme activity of maize phosphoenolpyruvate carboxylase transgenic rice

Authors: W.C.Li, J. Wang, Y.L. Sun, S.D. Ji, S.W. Guo

The morphology and photosynthetic enzyme activity were studied in maize phosphoenolpyruvate carboxylase transgenic rice and non-transgenic rice. The results showed that compared with non-transgenic rice, phosphoenolpyruvate carboxylase transgenic rice was taller and had a stronger stalk, wider leaves, and more exuberant root s.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.8
DOI:
10.4238/2015.December.1.8
Plant Genetics   Research Article

Computational identification of miRNAs and their targets in Phaseolus vulgaris

Authors: J. Han, H. Xie, M.L. Kong, Q.P. Sun, R.Z. Li and J.B. Pan

MicroRNAs (miRNAs) are a class of non-coding small RNAs that negatively regulate gene expression at the post-transcriptional level. Although thousands of miRNAs have been identified in plants, limited information is available about miRNAs in Phaseolus vulgaris, despite it being an important food legume worldwide. The high cons.. Read More»

Genet. Mol. Res. 13(1):
2014.January.17.16
DOI:
10.4238/2014.January.17.16
Human Genetics   Research Article

Matrix metalloproteinase-3 gene polymorphism and its mRNA expression in rheumatoid arthritis

Authors: M.J. Ma, H.C. Liu, X.Q. Qu, J.L. Wang

Matrix metalloproteinase-3 (MMP-3) can mediate the occurrence and development of rheumatoid arthritis (RA). The MMP3 promoter gene exhibits polymorphism with 5A/6A alleles. We investigated the correlation between the expression of MMP3 gene polymorphism and RA to provide an objective basis for prognosis evaluation. We enrolled.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.17
DOI:
10.4238/2015.December.1.17
Animal Genetics   Research Article

Polymorphisms associated with egg number at 300 days of age in chickens

Authors: H.P. Xu, H. Zeng, D.X. Zhang, X.L. Jia, C.L. Luo, M.X. Fang, Q.H. Nie and X.Q. Zhang

We looked for variations that could be associated with chicken egg number at 300 days of age (EN300) in seven genes of the hypothalamic-pituitary-gonadal axis, including gonadotrophin-releasing hormone-I (GnRH-I), GnRH receptor (GnRHR), neuropeptide Y (NPY), dopamine D2 receptor (DRD2), vasoactive intestinal polypeptide (VIP),.. Read More»

Genet. Mol. Res. 10(4):
2011.October.3.5
DOI:
10.4238/2011.October.3.5
Human Genetics   Research Article

Association of a transforming growth factor-�²1 polymorphism with acute coronary syndrome in a Chinese Han population

Authors: Y.N. Yang, B. Zhao, X.M. Li, X. Xie, F. Liu and B.D. Chen

Acute coronary syndrome (ACS) is a complex multifactorial and polygenic disorder that is thought to result from the interaction between an individual’s genetic makeup and various environmental factors. The aim of this study was to investigate the association of a transforming growth factor-β1 (TGF-β1) polymorph.. Read More»

Genet. Mol. Res. 13(3):
2014.April.3.2
DOI:
10.4238/2014.April.3.2
Animal Genetics   Research Article

Diversity of arthropod community in transgenic poplar-cotton ecosystems

Authors: D.J. Zhang,Z.Y. Lu,J.X. Liu,C.L. Li, M.S. Yang

Poplar-cotton agro-ecosystems are the main agricultural planting modes of plain cotton fields in China. Here, we performed a systematic survey of the diversity and population of arthropod communities in four different combination of poplar-cotton eco-systems, including I) non-transgenic poplar and non-transgenic cotton fields;.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.23
DOI:
10.4238/2015.December.1.23