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Gene

Human Genetics   Research Article

Lack of association between IL-6 -174G>C polymorphism and lung cancer: a meta-analysis

Authors: Y. Liu, X.L. Song, G.L. Zhang, A.M. Peng, P.F. Fu, P. Li, M. Tan, X. Li, M. Li and C.H. Wang

The objective of the current study was to assess the utility of 64-row helical computed tomography angiography (CTA) in the evaluation of extremity vascular traumas. The extremities from 17 clinical cases of suspected traumatic vascular damage were evaluated using 64-row helical CTA. To evaluate extremity vascular traumas using CTA, volume rendering, mult.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.19
DOI:
10.4238/2015.January.15.19
Animal Genetics   Research Article

Absence of the exon 1 coding sequence of the androgen receptor gene associated with teratozoospermia in a Brazilian population

Authors: W.E.J.C. Mesquita, M.S. Approbato, K.K.V.O. Moura, and R.S.A. Jesu�­no

The androgen receptor (AR) is a protein encoded by the AR gene, which when mutated may affect spermatogenesis, the process in which spermatozoa are produced; thus, AR mutations could lead to male infertility. We examined exon 1 of the AR gene in men with idiopathic infertility. Blood or semen samples from 111 infertile, oligoz.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr686
DOI:
10.4238/vol8-4gmr686
Human Genetics   Research Article

Construction and identification of recombinant adenovirus carrying human TIMP-1shRNA geneg

Authors: Y.L. Sun, H. Xie, H.L. Lin, Q. Feng and Y. Liu

The aim of this study was to construct the recombinant adenovirus carrying human TIMP-1shRNA gene expression system for preliminary identification to lay the foundation for the further study of gene therapy. Using the Adeno-XTM system, the recombinant adenovirus plasmid pAdeno-XTM green fluorescent protein (GFP)-tissue inhibitor of metalloprotease (TIMP)-.. Read More»

Genet. Mol. Res. 14(1):
2015.January.16.3
DOI:
10.4238/2015.January.16.3
Animal Genetics   Research Article

Estimates of genetic parameters for stayability and their associations with traits of economic interest in Gir dairy cows

Authors: R.M.O. Silva1,2, A.A. Boligon2, A.R. Fernandes3, A.E. Vercesi Filho4, L. El Faro4, H. Tonhati2, L.G. Albuquerque2 and A.B. Fraga1

The objective of the present study was to estimate genetic parameters for stayability at 60 months of age (STAY60) and its association with first lactation cumulative milk yield (P305), age at first calving (AFC), and first calving interval (FCI), in order to adopt these traits as selection criteria for longevity in Gir dairy cattle. Records for 2770 cows.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016958
DOI:
10.4238/gmr.15016958
Animal Genetics   Research Article

Genetic study of skin thickness and its association with postweaning growth in Nellore cattle: estimation of the genetic parameters

Authors: A.M. Maiorano1, M.C.S. Oliveira2, J.N.S.G. Cyrillo3, L.G. Albuquerque1,R.A. Curi4 and J.A.IIV. Silva4

The objective of the present study was to estimate genetic parameters for skin thickness (ST) and postweaning weight gain (PWG550) in Nellore cattle. Records were obtained from 152,392 Nellore animals born between 2001 and 2011. ST was measured in the posterior region of the animal’s scapula with a millimeter caliper. The animals were assigned to di.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017124
DOI:
10.4238/gmr.15017124
Animal Genetics   Research Article

Indirect selection of industrial tomato genotypes that are resistant to spider mites (Tetranychus urticae)

Authors: J.E. Baier, J.T.V. Resende, M.V. Faria, K. Schwarz and L. Meert

Acyl sugars present in the tomato Solanum lycopersicum ‘LA-716’ accession confer good levels of resistance to arthropod pests. The objective of the present study was to select F2 plants from the interspecific cross Solanum pennellii ‘LA-716’ x Solanum lycopersicum ‘Redenção’ to assess resistance to spider .. Read More»

Genet. Mol. Res. 14(1):
2015.January.16.8
DOI:
10.4238/2015.January.16.8
Plant Genetics   Research Article

Genetic control and transgressive segregation of zinc, iron, potassium, phosphorus, calcium, and sodium accumulation in cowpea (Vigna unguiculata) seeds

Authors: C.A. Fernandes Santos1 and L.S. Boiteux2

Cowpea crop, through combining a range of essential minerals with high quality proteins, plays an important role in providing nutritional security to human population living in semi-arid regions. Studies on genetics of biofortification with essential minerals are still quite scarce, and the major objective of the present study was to provide genetic informat.. Read More»

Genet. Mol. Res. 14(1):
2015.January.16.10
DOI:
10.4238/2015.January.16.10
Plant Genetics   Research Article

Genetic diversity of Saccharum officinarum accessions in Pakistan as revealed by random amplified polymorphic DNA

Authors: F.A. Khan, A. Khan, F.M. Azhar and S. Rauf

Genetic diversity of 20 sugarcane accessions in Pakistan was studied using 21 random amplified polymorphic DNA markers. The mean genetic distance between the cultivars was 39.03%, demonstrating that a large part of the genome is similar among the accessions. This probably arises from a lack of parental diversity, with few clon.. Read More»

Genet. Mol. Res. 8(4):
Human Genetics   Research Article

Genetic variability of CYP3A4 in a heterogeneous Brazilian population from Maranh�£o

Authors: S.C. Moutinho Monteiro1, I.H. de Sousa1, I.K. Pereira Belfort1,J.D. Nunes1, B.A. Sousa Penha1, M. dos Santos2, I. Drumond Louro3 and I.D.C. Guerreiro da Silva4

Inter-individual variability in drug metabolism may result in adverse drug responses. Pharmacogenetic studies have shown that polymorphisms in drug metabolizing enzymes may contribute to this variability. Among these enzymes, CYP3A4 is responsible for metabolizing over 50% of the clinically used drugs. The Brazilian population is composed of people with N.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017275
DOI:
10.4238/gmr.15017275
Plant Genetics   Research Article

Cloning and characterization of SPL-family genes in the peanut (Arachis hypogaea L.)

Authors: M. Li1*, S.Z. Zhao1*, C.Z. Zhao1, Y. Zhang1, H. Xia1, J. Lopez-Baltazar2, S.B. Wan1 and X.J. Wang1

SQUAMOSA promoter-binding protein-like (SPL) proteins play crucial roles in plant growth, development, and responses to environmental stressors. The peanut (Arachis hypogaea L.) is a globally important oil crop. In this study, we cloned the full-length cDNA of 15 SPLs in the peanut by transcriptome sequencing and rapid amplification of cDNA ends, and anal.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017344
DOI:
10.4238/gmr.15017344