Gene
Genetic diversity of turmeric germplasm (Curcuma longa; Zingiberaceae) identified by microsatellite markers
Authors: M.S. Sigrist, J.B. Pinheiro, J.A. Azevedo Filho and M.I. Zucchi
Turmeric (Curcuma longa) is a triploid, vegetatively propagated crop introduced early during the colonization of Brazil. Turmeric rhizomes are ground into a powder used as a natural dye in the food industry, although recent research suggests a greater potential for the development of drugs and cosmetics. In Brazil, little is k.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1047
- DOI:
- 10.4238/vol10-1gmr1047
A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer
Authors: M.A. Proen�§a, G.M.M. Fernandes, A. Russo, R.B. Lelis, J.G. Netinho, G.S. Cunrath, A.E. Silva, E.M. Goloni-Bertollo and E.C. Pavarino
Polymorphisms in genes encoding P450 cytochrome enzymes may increase the risk of sporadic colorectal cancer (SCRC). Here we investigated the association between SCRC and CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in a case-control study. Moreover, we sought to determine any possible associations between this disease and the sociodemographic factors. We.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.10
- DOI:
- 10.4238/2015.December.22.10
An insight in the genetic control and interrelationship of some quality traits in Brassica napus
Authors: S. Ahmad, H.A. Sadaqat, M.H.N. Tahir and F.S. Awan
A study on three leading lines (KN-256, KN-257, and KN-258) of Brassica napus and an approved variety, Punjab-Sarson, was conducted to gain insight into the genetic control of some quality traits using generation mean analysis. Our results showed that additive gene action predominated in the inheritance of oil content and erucic acid in cross KN-256 x KN-.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.19
- DOI:
- 10.4238/2015.December.22.19
Comparison of eight methods of genomic DNA extraction from babassu
Authors: J.P.G. Viana, A.N.C. Borges, A.C.A. Lopes, R.L.F. Gomes, F.B. Britto, P.S.C. Lima and S.E.S. Valente
Babassu (Orbignya phalerata Martius) is one of the most important palms in Brazil because of the largest morphological variation, wide geographic distribution, and high socio-economic importance. The diversity present in babassu germplasm should be protected against loss to ensure their use with high productivity. Study of the available variability in pop.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.26
- DOI:
- 10.4238/2015.December.22.26
Investigation into withdrawal of entecavir after 20 months in an HBsAb-positive patient who received HBsAg allogeneic stem cell transplantation
Authors: J. Peng, W.F. Luo, B. Zhou and W.Q. Wen
Hepatitis B virus (HBV) infection of donors and recipients is not an absolute contraindication for allogeneic stem cell transplantation (allo-HSCT). We studied a patient who received allo-HSCT from an HBsAg-positive donor. The patient was administered long-term immunosuppressive therapy and treated with the oral anti-viral medication, entecavir (ETV). Dur.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.22
- DOI:
- 10.4238/2015.December.22.22
Sevoflurane induces neurotoxicity in young mice through FAS/FASL signaling
Authors: Q. Song, Y.L. Ma, J.Q. Song, Q. Chen, G.S. Xia, J.Y. Ma, F. Feng, X.J. Fei and Q.M. Wang
Sevoflurane, the most widely used anesthetic in clinical practice, has been shown to induce apoptosis, inhibit neurogenesis, and cause learning and memory impairment in young mice. However, the underlying mechanism is still unknown. In this study, wild-type and the FAS- or FAS ligand (FASL)-knockout mice (age 7 days) were exposed to sevoflurane or pure ox.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.32
- DOI:
- 10.4238/2015.December.22.32
Isolation and analysis of cell-free fetal DNA from maternal peripheral blood in Chinese women
Authors: W.C. Yang, L. Zhu, Y.M. Qiu, B.X. Zhou, J.L. Cheng, C.L. Wei, H.C. Chen, L.Y. Li, X.D. Fu and J.J. Fu
Non-invasive prenatal diagnosis is used to detect the genetic material of the fetus by isolating the cell-free fetal DNA (cffDNA) from maternal peripheral blood. In order to establish an isolation method for cffDNA from maternal peripheral blood in Chinese women, the cffDNA was acquired with a two-step centrifugation using a QlAamp DNA Blood mini kit. The.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.34
- DOI:
- 10.4238/2015.December.22.34
Expression patterns of the STAG gene in intact and regenerating planarians (Dugesia japonica)
Authors: Z.Q. Yuan, B.S. Zhao and J.Y. Zhang
We examined the spatial and temporal expression of the planarian Dugesia japonica STAG-related gene (DjStag), in both intact and regenerating planarians, by whole-mount in situ hybridization and relative quantitative real-time PCR. The first localized transcripts of DjStag were detected in the blastemas three days after amputa.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1042
- DOI:
- 10.4238/vol10-1gmr1042
Genetic characterization of papaya plants (Carica papaya L.) derived from the first backcross generation
Authors: H.C.C. Ramos, M.G. Pereira, F.F. Silva, L.S.A. Gon�§alves, F.O. Pinto, G.A. de Souza Filho and T.S.N. Pereira
The limited number of papaya varieties available reflects the narrow genetic base of this species. The use of backcrossing as a breeding strategy can promote increases in variability, besides allowing targeted improvements. Procedures that combine the use of molecular markers and backcrossing permit a reduction of the time req.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1004
- DOI:
- 10.4238/vol10-1gmr1004
Cloning and characterization of the nicotianamine synthase gene in Eruca vesicaria subsp sativa
Authors: B.L. Huang, C. Cheng, G.Y. Zhang, J.J. Su, Y. Zhi, S.S. Xu, D.T. Cai, X.K. Zhang and B.Q. Huang
Nicotianamine (NA) is a ubiquitous metabolite in plants that bind heavy metals, is crucial for metal homeostasis, and is also an important metal chelator that facilitates long-distance metal transport and sequestration. NA synthesis is catalyzed by the enzyme nicotianamine synthase (NAS). Eruca vesicaria subsp sativa is highly tolerant to Ni, Pb, and Zn. .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.38
- DOI:
- 10.4238/2015.December.22.38