Gene
Polymorphisms in the PPAR�³ gene and their association with metabolic syndrome in Uyghurs and Kazakhs from Xinjiang, China
Authors: J. Chen, R.L. Ma, H. Guo, Y.S. Ding, J.Y. Zhang, J.M. Liu, M. Kerm, M. Zhang, S.Z. Xu, S.G. Li and S.X. Guo
We investigated the association between polymorphisms rs1801282 and rs3856806 of the PPARγ gene and metabolic syndrome (MS) among Uyghurs and Kazakhs. Mass spectrometry techniques were used to detect the PPARγ genotypes rs1801282 and rs3856806 in 987 subjects, CC genotype and C allele frequencies were 83.6 and 91.7%, respectively, at rs1801282.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.1
- DOI:
- 10.4238/2015.June.11.1
Estimating additive and dominance variances for complex traits in pigs combining genomic and pedigree information
Authors: E.V. Costa, D.B. Diniz, R. Veroneze, M.D.V. Resende, C.F. Azevedo, S.E.F. Guimaraes, F.F. Silva and P.S. Lopes
Knowledge of dominance effects should improve genetic evaluations, provide the accurate selection of purebred animals, and enable better breeding strategies, including the exploitation of heterosis in crossbreeds. In this study, we combined genomic and pedigree data to study the relative importance of additive and dominance genetic variation in growth and.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.4
- DOI:
- 10.4238/2015.June.11.4
Screening the first set of polymorphic microsatellite loci in Lunella coronata granulata (Turbinidae)
Authors: Z.B. Li, Q.H. Li, J.B. Shangguan, Y.F. Ning and G. Dai
Lunella coronata granulata, from the family Turbinidae, is an economically important species. The first set of 10 polymorphic microsatellite loci was screened from L. coronata granulata, and 30 individuals were used to analyze the degree of polymorphism in these loci. The level of observed and expected heterozygosity was 0.0667-0.7333 and 0.0644-0.6628, r.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.6
- DOI:
- 10.4238/2015.June.11.6
Isolation and characterization of microsatellite markers in Atrina vexillum Born
Authors: Y.F. Ning, Z.B. Li, Y.S. Huang, X.Q. Mao, B.B. Li, Y. Yuan and J.B. Shangguan
Atrina vexillum Born is an economically valuable species, widely distributed in the coastal waters of temperate and tropical areas of the Asia Pacific region. Twenty one novel microsatellite loci were identified in the genome of A. vexillum Born using the protocol for fast isolation by amplified fragment length polymorphism of.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027204
- DOI:
- 10.4238/gmr.15027204
Prediction of genetic risk factors of atherosclerosis using various bioinformatic tools
Authors: H.X. Wang and Y.X. Zhao
The aim of this study was to identify potential markers of atherosclerosis development in familial hypercholesterolemia (FH) patients. GSE13985 microarray data, generated using blood samples from 5 FH patients and 5 matched controls, was downloaded from the Gene Expression Omnibus. Differentially expressed genes (DEGs) between.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027347
- DOI:
- 10.4238/gmr.15027347
Assessment of genetic relationship in Persea spp by traditional molecular markers
Authors: J.C. Reyes-Alem�¡n, E. Valadez-Moctezuma and A.F. Barrientos-Priego
Currently, the reclassification of the genus Persea is under discussion with molecular techniques for DNA analysis representing an alternative for inter- and intra-specific differentiation. In the present study, the traditional random-amplified polymorphic DNA (RAPD) and the inter simple sequence repeat (ISSR) markers were use.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027359
- DOI:
- 10.4238/gmr.15027359
Post-transcriptional silencing of the SGE1 gene induced by a dsRNA hairpin in Fusarium oxysporum f. sp cubense, the causal agent of Panama disease
Authors: J.S. Fernandes, P.C.S. Angelo, J.C. Cruz, J.M.M. Santos, N.R. Sousa and G.F. Silva
Fusarium oxysporum f. sp cubense (Foc), the causal agent of Panama disease, is responsible for economic losses in banana crops worldwide. The identification of genes that effectively act on pathogenicity and/or virulence may contribute to the development of different strategies for disease control and the production of resista.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027941
- DOI:
- 10.4238/gmr.15027941
BacPP: a web-based tool for Gram-negative bacterial promoter prediction
Authors: S. de Avila e Silva, D.L. Notari, F.A. Neis, H.G. Ribeiro and S. Echeverrigaray
Bacterial Promoter Prediction (BacPP) is a tool used to predict given sequences as promoters of Gram-negative bacteria according to the σ factor that recognizes it. The first version of BacPP was implemented in Python language in a desktop version without a friendly interface. For this reason, a web version of BacPP is n.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027973
- DOI:
- 10.4238/gmr.15027973
Comparison of EGFR mutation rates in lung adenocarcinoma tissue and pleural effusion samples
Authors: Y. Guan, Z.J. Wang, L.Q. Wang, D.F. Hua and J. Liu
The goal of the current study was to investigate the differences in epidermal growth factor receptor (EGFR) mutation rates in tumor tissue and pleural effusion specimens from patients with lung adenocarcinoma. PCR amplification and gene sequencing were used to detect EGFR mutations in exons 18, 19, 20, and 21 in tumor tissue a.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027001
- DOI:
- 10.4238/gmr.15027001
Sheep YAP1 temporal and spatial expression trend and its relation with MyHCs expression
Authors: W. Gao, W. Sun, R. Su, X.Y. Lv, Q.Z. Wang, D. Li, H.H. Musa, L. Chen, H. Zhou, H.S. Xu and W.H. Hua
RT-PCR was used to study the temporal and spatial pattern of Yes-associated protein 1 (YAP1) and myosin heavy chain (MyHC) expression in four different skeletal muscles (i.e., longissimus dorsi muscle, soleus muscle, gastrocnemius muscle, and extensor digitorum longus) and three growth stages (i.e., 2 days old, 2 and 6 months .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027260
- DOI:
- 10.4238/gmr.15027260