Gene
Association between ACP1 genetic polymorphism and favism
Authors: V. Polzonetti, V. Passini and N. Lucarini
An association between favism (a hemolytic reaction to consumption of fava beans), glucose-6-phosphate dehydrogenase deficiency (G6PD-) and acid phosphatase locus 1 (ACP1) phenotypes has been reported; the frequency of carriers of the pa and pc ACP1 alleles was found to be significantly higher in G6PD- individuals showing favi.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1062
- DOI:
- 10.4238/vol10-2gmr1062
Molecular mapping of quantitative trait loci for drought tolerance in maize plants
Authors: H. Rahman, S. Pekic, V. Lazic-Jancic, S.A. Quarrie, S.M.A. Shah, A. Pervez and M.M. Shah
Drought tolerance is one of the most important but complex traits of crops. We looked for quantitative trait loci (QTLs) that affect drought tolerance in maize. Two maize inbreds and their advanced lines were evaluated for drought-related traits. A genetic linkage map developed using RFLP markers was used to identify QTLs asso.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1139
- DOI:
- 10.4238/vol10-2gmr1139
Protective effect of icariin on kidney in 5/6 nephrectomized rats and its mechanism
Authors: S.R. Liang, J.W. Bi, Z.L. Guo, Y. Bai and Z. Hu
The aim of this study was to investigate the renal protective effect of icariin in 5/6 nephrectomized rats and the molecular mechanisms involved. Forty male Sprague-Dawley rats were randomly divided into 5 groups: sham-operated group, 5/6 nephrectomy model group, icariin groups (20 and 40 mg/kg), and benazepril group. After 12.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.10
- DOI:
- 10.4238/2014.August.25.10
Identification of 18 genes encoding necrosis-inducing proteins from the plant pathogen Phytophthora capsici (Pythiaceae: Oomycetes)
Authors: B.Z. Feng, P.Q. Li, L. Fu, B.B. Sun and X.G. Zhang
Phytophthora capsici is an aggressive plant pathogen that affects solanaceous and cucurbitaceous hosts. Necrosis-inducing Phytophthora proteins (NPPs) are a group of secreted toxins found particularly in oomycetes. Several NPPs from Phytophthora species trigger plant cell death and activate host defense gene expression. We iso.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1248
- DOI:
- 10.4238/vol10-2gmr1248
Development of a cassava core collection based on single nucleotide polymorphism markers
Authors: E.J. Oliveira, C.F. Ferreira, V.S. Santos and G.A.F. Oliveira
Single nucleotide polymorphism (SNP) markers were used in the largest cassava (Manihot esculenta Crantz) germplasm collection from Brazil to develop core collections based on the maximization strategy. Subsets with 61, 64, 84, 128, 256, and 384 cassava accessions were selected and named PoHEU, MST64, PoRAN, MST128, MS.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.25.11
- DOI:
- 10.4238/2014.August.25.11
Polymorphisms in the delta-like 2 homolog gene and their association with growth and meat-quality traits in Qinchuan cattle
Authors: N. Yang, L.S. Zan, Y.K. Li, J.B. Gao, X.H. Ma, C.Z. Fu, H. Wang and C. Adoligbe
The delta-like 2 homolog (DLK2) modulates adipogenesis, hematopoiesis, osteogenesis, and other cell-differentiation processes. In the present study, we detected potential polymorphisms in the DLK2 gene in 604 individuals of Qinchuan cattle by using PCR-RFLP and DNA-sequencing methods. Herein, we identified five novel single-nu.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.20
- DOI:
- 10.4238/2014.March.24.20
Genetic assessment of the Atlantic Forest bristle porcupine, Chaetomys subspinosus (Rodentia: Erethizontidae), an endemic species threatened with extinction
Authors: C.G. Oliveira, R.A. Martinez, G.A.F. Gin�©, D.M. Faria and F.A. Gaiotto
The bristle-spined porcupine, Chaetomys subspinosus, an endemic rodent from Atlantic Forest, was considered to be abundant in the recent past, but population reductions due to habitat loss and expansion of human activities caused this species to be included in the “vulnerable” category of the World Conservation Uni.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1039
- DOI:
- 10.4238/vol10-2gmr1039
TP53 gene polymorphisms at codons 11, 72, and 248 and association with endometriosis in a Brazilian population
Authors: C.M. Camargo-Kosugi, P. D�Amora, J.P.F.O. Kleine, C.V. Carvalho, H. Sato, E. Schor and I.D.C.G. Silva
We evaluated the association between TP53 gene polymorphisms and endometriosis in Brazilian women. Genomic DNA was extracted from swabs of buccal cells collected from hospital patients. TP53 gene polymorphisms were investigated at three codons: TP53*11 Glu/Gln or Lys (GAG->CAG or AAG), TP53*.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.26.1
- DOI:
- 10.4238/2014.August.26.1
Relationship between the cholesterol ester transfer protein TaqIB polymorphism and the lipid-lowering effect of atorvastatin in patients with coronary atherosclerotic heart disease
Authors: J. Li, L. Zhang, N.Z. Xie, B. Deng2, L.X. Lv and L.Q. Zheng
This study aimed to investigate the relationship between the cholesterol ester transfer protein (CETP) gene TaqIB polymorphism and the lipid-lowering effect of atorvastatin in patients with coronary atherosclerotic heart disease. Two hundred eighty-eight patients were divided into a control group, an acute coronary syndrome (A.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.21
- DOI:
- 10.4238/2014.March.24.21
Association of variable number of tandem repeats polymorphism in the IL-4 gene with end-stage renal disease in Malaysian patients
Authors: R. Vasudevan, M.N. Norhasniza and I. Patimah
Variable number of tandem repeats (VNTR) polymorphism in the interleukin 4 (IL-4) gene has been associated with end-stage renal disease (ESRD) subjects in many different populations, although with conflicting results. We determined the 70 bp of VNTR polymorphism at intron 3 of the IL-4 gene in Malaysian ESRD subjects. Buccal c.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1066
- DOI:
- 10.4238/vol10-2gmr1066