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Gene

Human Genetics   Research Article

Correlation analysis of the PNPLA7 gene polymorphism and susceptibility to menstrual disorder

Authors: Y. Su, G.L. Kong, Y.L. Su, Y. Zhou, L.F. Lv, Q. Wang, B.P. Huang,R.Z. Zheng, Q.Z. Li, H.J. Yuan and Z.G. Zhao

We examined the correlation between PNPLA7 gene polymorphisms at the rs61754920 and rs11137410 loci and menstrual disorder in women of reproductive age in the Central Plain. Genomic DNA was extracted from peripheral blood; polymerase chain reaction-ligase detection reaction and SNaPshot genotyping were used to detect polymorphisms in the rs61754920 and rs.. Read More»

Genet. Mol. Res. 14(1):
2015.March.6.20
DOI:
10.4238/2015.March.6.20
Human Genetics   Research Article

Mechanism of the reversal effect of mifepristone on drug resistance of the human cervical cancer cell line HeLa/MMC

Authors: H. Chen, J. Duan and F. Zuo

We examined the ability of mifepristone to reverse the in vitro drug resistance of human cervical cancer cells resistant to mitomycin-C (HeLa/MMC) cells and investigated the mechanism of this effect. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was performed to detect the drug resistance of HeLa/MMC cel.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.27.14
DOI:
http://dx.doi.org/10.4238/2014.February.27.14
Plant Genetics   Research Article

Assessment of genetic diversity of bermudagrass germplasm from southwest China and Africa by using AFLP markers

Authors: Y. Ling, L.K. Huang, X.Q. Zhang, X. Ma, W. Liu, S.Y. Chen and H.D. Yan

Cynodon dactylon (L.) Pers. var. dactylon (common bermudagrass) is widely distributed geographically between approximately 45°N and 45°S latitude, penetrating to approximately 53°N latitude in Europe. The extensive variation of morphological and adaptive characteristics of the taxon has been substantially documented, but information is lacking.. Read More»

Genet. Mol. Res. 14(1):
2015.March.13.1
DOI:
10.4238/2015.March.13.1
Human Genetics   Research Article

Association between the LXR�± polymorphism and stroke in a Chinese population

Authors: J.S. Yang, J.J. Hao, S.S. Wang, Z.F. Zhu, Q. Fang, H. Bao and H.P. Zhang

We examined the relationship between the liver X receptor α gene (LXRα) polymorphism and the susceptibility to stroke. We utilized the single fluorescent-labeled probe technique to detect the genotype of rs12221497 in the LXRα gene in 400 stroke patients and 400 healthy control subjects. The difference in genotype distribution between th.. Read More»

Genet. Mol. Res. 14(1):
2015.March.13.2
DOI:
10.4238/2015.March.13.2
Microbial Genetics   Research Article

Endophytic bacteria from Piper tuberculatum Jacq.: isolation, molecular characterization, and in vitro screening for the control of Fusarium solani f. sp piperis, the causal agent of root rot disease in black pepper (Piper nigrum L.)

Authors: S.B. Nascimento, A.M. Lima, B.N. Borges and C.R.B. de Souza

Endophytic bacteria have been found to colonize internal tissues in many different plants, where they can have several beneficial effects, including defense against pathogens. In this study, we aimed to identify endophytic bacteria associated with roots of the tropical piperaceae Piper tuberculatum, which is known for itsresistance to infection by Fusariu.. Read More»

Genet. Mol. Res. 14(3):
2015.July.3.32
DOI:
10.4238/2015.July.3.32
Human Genetics   Research Article

Multibreed genetic evaluation in bovines using simulated data employing a composite population

Authors: A.L. Bocchi, H.N. Oliveira, J.B.S. Ferraz and J.P. Eler

Genetic evaluations in Brazil are performed within each animal breed; however, with the wide range of extant genetic groups in the country and the increased use of genetic crossing as a form of rapid meat production, more elaborate programs that can jointly evaluate animals of different genetic groups are needed. Genetic evalu.. Read More»

Genet. Mol. Res. 15(4):
gmr.15048382
DOI:
10.4238/gmr.15048382
Animal Genetics   Research Article

Genetic diversity and classification of Tibetan yak populations based on the mtDNA COIII gene

Authors: Q.Q. Song, Z.X. Chai, J.W. Xin, S.J. Zhao, Q.M. Ji, C.F. Zhang, Z.J. Ma and J.C. Zhong

To determine the level of genetic diversity and phylogenetic relationships among Tibetan yak populations, the mitochondrial DNA cytochrome c oxidase subunit 3 (COIII) genes of 378 yak individuals from 16 populations were analyzed in this study. The results showed that the length of cytochrome c oxidase subunit 3 gene sequences was 781 bp, with nucleotide .. Read More»

Genet. Mol. Res. 14(1):
2015.March.13.3
DOI:
10.4238/2015.March.13.3
Human Genetics   Research Article

Genetic divergence through joint analysis of morphoagronomic and molecular characters in accessions of Jatropha curcas

Authors: C.N. Pestana-Caldas, S.A. Silva, E.L. Machado, D.R. de Souza,E.C. Cerqueira-Pereira and M.S. Silva

The aim of this study was to investigate the genetic divergence between accessions of Jatropha curcas through joint analysis of morphoagronomic and molecular characters. To this end, we investigated 11 morphoagronomic characters and performed molecular genotyping, using 23 inter-simple sequence repeat (ISSR) primers in 46 acce.. Read More»

Genet. Mol. Res. 15(4):
gmr.15048385
DOI:
10.4238/gmr.15048385
Human Genetics   Research Article

Genetic diversity in Tunisian populations of faba bean (Vicia faba L.) based on morphological traits and molecular markers

Authors: I.Z. Backouchi, M. Aouida, N. Khemiri and M. Jebara

Genetic diversity within Vicia faba L. is key to the genetic improvement of this important species. In this study, morphological traits and RAPD molecular markers were used to assess the levels of polymorphism across 12 Tunisian populations, three major and nine minor from different locations. Analysis of morphological traits indicated that the three majo.. Read More»

Genet. Mol. Res. 14(3):
2015.July.13.2
DOI:
10.4238/2015.July.13.2
Animal Genetics   Research Article

Genetic diversity and population structure of Kazakh horses (Equus caballus) inferred from mtDNA sequences

Authors: M. Gemingguli, K.R. Iskhan, Y. Li, A. Qi, W. Wunirifu, L.Y. Ding and A. Wumaierjiang

The Kazakh horse is an important old horse breed in Xinjiang. They have contributed greatly to the breeding and improvement of other local horse breeds, yet their genetic diversity and population structure are not well understood. In the present study, we evaluated the genetic diversity of Kazakh horses and their relationship .. Read More»

Genet. Mol. Res. 15(4):
gmr.15048618
DOI:
10.4238/gmr.15048618