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Gene

Animal Genetics   Research Article

Genetic markers of body composition and carcass quality in grazing Brangus steers

Authors: M.C. Baeza, P.M. Corva, L.A. Soria, G. Rincon, J.F. Medrano, E. Pavan, E.L. Villarreal, A. Schor, L. Melucci, C. Mezzadra and M.C. Miquel

The somatotropic axis is a major regulatory pathway of energy metabolism during postnatal growth in mammals. Genes involved in this pathway influence many economically important traits. The association of selected SNPs in these genes with carcass traits was examined in grazing Brangus steers. These traits included final live w.. Read More»

Genet. Mol. Res. 10(4):
2011.December.19.3
DOI:
10.4238/2011.December.19.3
Human Genetics   Research Article

Sulcus vocalis: evidence for autosomal dominant inheritance

Authors: R.H.G. Martins, T.M. Gon�§alves, D.S. Neves, T.A. Fracalossi, E.L.M. Tavares and D. Moretti-Ferreira

We found evidence of autosomal dominant hereditary transmission of sulcus vocalis. Four dysphonic patients from three generations of the same family were submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy (one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all four pat.. Read More»

Genet. Mol. Res. 10(4):
2011.December.19.5
DOI:
10.4238/2011.December.19.5
Microbial Genetics   Research Article

Alteration of coenzyme specificity of malate dehydrogenase from Streptomyces coelicolor A3(2) by site-directed mutagenesis

Authors: Y.D. Ge, P. Song, Z.Y. Cao, P. Wang and G.P. Zhu

We describe here for the first time the alteration of coenzyme specificity of malate dehydrogenase (MDH) from Streptomyces coelicolor A3(2) (ScMDH). In the present study, we replaced four amino acid residues in the Rossmann fold (βB-αC) region of NADH-dependent ScMDH by site-directed mutagenesis with those of NADPH-dependent MDH (Glu42.. Read More»

Genet. Mol. Res. 13(3):
2014.July.29.3
DOI:
10.4238/2014.July.29.3
Animal Genetics   Original Articles

Adaptation of a low-cost medium-throughput genotyping system for ovine prion protein gene polymorphims associated with scrapie

Authors: P. Ianella, C.M. McManus, S.R. Paiva and A.R. Caetano

Resistance and susceptibility to scrapie in sheep have been associated with SNPs located at codons 136, 154 and 171 of the prion protein (PRNP) gene. Many countries have sheep breeding programs selecting for resistance to scrapie based on the genotyping of these SNPs. We adapted a fast and robust method for genotyping sheep fl.. Read More»

Genet. Mol. Res. 10(4):
2011.December.20.2
DOI:
10.4238/2011.December.20.2
Plant Genetics   Research Article

Population genetic structure of the tropical tree species Aegiphila sellowiana (Lamiaceae)

Authors: C. Medri, E.A. Ruas, C.F. Ruas, P.S. Medri, M.E. Medri and P.M. Ruas

The Tibagi River, located in southern Brazil, is associated with a significant degree of environmental heterogeneity, along its 550 km extension. There is concern about the integrity of this river’s ecosystem, as human interference has been increasing. Aegiphila sellowiana (Lamiaceae) is an important pioneer tree species.. Read More»

Genet. Mol. Res. 10(4):
2011.December.20.3
DOI:
10.4238/2011.December.20.3
Animal Genetics   Research Article

Two splice variants of the bovine lactoferrin gene identified in Staphylococcus aureus isolated from mastitis in dairy cattle

Authors: J.M. Huang, Z.Y. Wang, Z.H. Ju, C.F. Wang, Q.L. Li, T. Sun, Q.L. Hou, S.Q. Hang, M.H. Hou and J.F. Zhong

Bovine lactoferrin (bLF) is a member of the transferrin family; it plays an important role in the innate immune response. We identified novel splice variants of the bLF gene in mastitis-infected and healthy cows. Reverse transcription-polymerase chain reaction (RT-PCR) and clone sequencing analysis were used to screen the spli.. Read More»

Genet. Mol. Res. 10(4):
2011.December.21.1
DOI:
10.4238/2011.December.21.1
Human Genetics   Research Article

Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population

Authors: X.P. Hu, Z.Q. Li, J.Y. Zhou, Z.H. Yu, J.M. Zhang and M.L. Guo

Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibi.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.15
DOI:
http://dx.doi.org/10.4238/2015.September.28.15
Animal Genetics   Research Article

Associated analysis of single nucleotide polymorphisms found on exon 3 of the IGF-1 gene with Tibetan miniature pig growth traits

Authors: M. Yue, Y.G. Tian, Y.J. Wang, Y. Gu1, N. Bayaer, Q. Hu and W.W. Gu,

The IGF-1 gene is an important regulating factor that has a growth-promoting effect on growth hormone. The IGF-1 gene promotes muscle cell differentiation in the muscle cell formation process. The IGF-1 gene also regulates the growth of skeletal muscle during skeletal muscle growth. In addition, the IGF-1 gene plays an importa.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.27.11
DOI:
http://dx.doi.org/10.4238/2014.February.27.11
Plant Genetics   Research Article

Analysis of genetic relationships and identification of lily cultivars based on inter-simple sequence repeat markers

Authors: G.F. Cui*, L.F. Wu*, X.N. Wang, W.J. Jia, Q. Duan, L.L. Ma, Y.L. Jiang and J.H. Wang

Inter-simple sequence repeat (ISSR) markers were used to discriminate 62 lily cultivars of 5 hybrid series. Eight ISSR primers generated 104 bands in total, which all showed 100% polymorphism, and an average of 13 bands were amplified by each primer. Two software packages, POPGENE 1.32 and NTSYSpc 2.1, were used to analyze the.. Read More»

Genet. Mol. Res. 13(3):
2014.July.29.5
DOI:
10.4238/2014.July.29.5
Animal Genetics   Research Article

Genotyping in the Brazilian Criollo Horse Stud Book: resources and perspectives

Authors: M.A.P. Costa, R.M.C. Bressel, D.B. Almeida, P.A. Oliveira, L.N. Bassini, C.G.A. Moreira, V.H.B. Manzke, F. Siewerdt and H.L.M. Moreira

The goal of this research was to evaluate the ability of the genotyping information available in the Brazilian Criollo Horse Stud Book to describe the genetic variability of the breed and the exclusion probability determined in comparative tests. Altogether, two softwares were used in the analyses of the available genotypes: C.. Read More»

Genet. Mol. Res. 9(3):
vol9-3gmr854
DOI:
10.4238/vol9-3gmr854