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Endometriosis

Human Genetics   Research Article

Association between the epidermal growth factor gene polymorphism and endometriosis in women from Brazil

Authors: C.B.N. Oliveira, P. Falagan-Lotsch, M.G. Souza, R.P. Santos, F. Encinas, H. Teles, R.B. Lasmar, L.B. Duarte, J.M. Granjeiro and I.A. Penna

The aim of this study was to verify the association between the epidermal growth factor (EGF) +61 G/A polymorphism and the susceptibility to endometriosis using a case-control design study. The control group included fertile women without endometriosis and the case group included endometriosis patients. Polymerase chain reacti.. Read More»

Genet. Mol. Res. 13(3):
2014.September.5.8
DOI:
10.4238/2014.September.5.8
Medical Genetics   Research Article

GSTM1 and GSTT1 polymorphisms in endometriosis in women from Goi�¡s, Brazil

Authors: A.B. Frare, A.M. Barbosa, I.R. Costa, S.R. Souza, R.C.P.C. Silva, B.M. Bordin, C.L. Ribeiro J�ºnior and K.K.V.O. Moura

Endometriosis is a gynecologic pathology with a high prevalence and unknown etiology. Therefore, an increasing number of studies has been undertaken to search for associations between endometriosis and alterations or polymorphisms in candidate genes, including glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1). We analyze.. Read More»

Genet. Mol. Res. 12(3):
2013.August.2.1
DOI:
10.4238/2013.August.2.1
Microbial Genetics   Research Article

Vascular endothelial growth factor gene polymorphisms contribute to the risk of endometriosis: an updated systematic review and meta-analysis of 14 case-control studies

Authors: Y.Z. Li, L.J. Wang, X. Li, S.L. Li, J.L. Wang, Z.H. Wu, L. Gong and X.D. Zhang

Endometriosis is a chronic gynecological disease defined as the presence of the endometrium outside the uterine cavity. Endometriosis is a multifactorial and polygenic disease in which angiogenesis may be implicated. Angiogenesis is under the control of numerous inducers, including vascular endothelial growth factor (VEGF). Many studies have reported that.. Read More»

Genet. Mol. Res. 12(2):
2013.April.2.20
DOI:
10.4238/2013.April.2.20
Medical Genetics   Research Article

RsaI polymorphism of the ER�² gene in women with endometriosis

Authors: R.C.P.C. Silva, I.R. Costa, B.M Bordin, C.T.X. Silva, S.R. Souza, C.L.R. J�ºnior, A.B. Frare and K.K.V.O. Moura

We examined the frequency of RsaI polymorphism of the ERβ gene in 54 patients diagnosed with endometriosis and 46 controls. Peripheral blood was collected from women undergoing laparoscopy with a confirmed diagnosis of endometriosis. Polymorphisms of the ERβ gene and p53 were assessed by PCR and analyzed on 2% agaros.. Read More»

Genet. Mol. Res. 10(1):
vol10-1gmr940
DOI:
10.4238/vol10-1gmr940