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Human Genetics   Research Article

Effect of pulsed electromagnetic field therapy on the osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells

Authors: T. Lu, Y.X. Huang, C. Zhang, M.X. Chai and J. Zhang

We investigated the effects of pulsed electromagnetic fields (PEMFs) of 20 Hz/2 mT on the osteogenic and adipogenic differentiation of bone marrow stem cells (BMSCs). Sprague Dawley rat BMSCs were isolated and cultured in vitro. The BMSCs of the third passage were obtained and stimulated by PEMFs of 20 Hz/2 mT. The alkaline phosphatase (ALP) activity was .. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.5
DOI:
http://dx.doi.org/10.4238/2015.September.28.5
Human Genetics   Research Article

Mechanism underlying the bio-effects of an electromagnetic field based on the Huang-Ferrell model

Authors: D.Y. Geng, G. Hu, L. Wang, N. Jia and F.X. Wang

To understand the beneficial and harmful bio-effects of extremely low frequency electromagnetic fields, we studied the MAPK/ERK signaling pathway based on the Huang-Ferrell model. The sensitivity analysis method was used to study the influence of the model parameters on the activity of ERK, and to further investigate the key b.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028796
DOI:
10.4238/gmr.15028796

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