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Differentially Expressed Genes

Human Genetics   Research Article

Screening for key genes associated with invasive ductal carcinoma of the breast via microarray data analysis

Authors: J.L. Huan, X. Gao, L. Xing, X.J. Qin, H.X. Qian, Q. Zhou and L. Zhu

The aim of this study was to identify key genes related to invasive ductal carcinoma (IDC) of the breast by analyzing gene expression data with bioinformatic tools. Microarray data set GSE31138 was downloaded from Gene Expression Omnibus, including 3 breast cancer tissue samples and 3 normal controls. Differentially expressed .. Read More»

Genet. Mol. Res. 13(3):
2014.September.29.5
DOI:
10.4238/2014.September.29.5
Animal Genetics   Research Article

Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens

Authors: B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen

Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling splee.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.32
DOI:
10.4238/2015.December.16.32
Bioinformatics   Research Article

Critical genes in head and neck squamous cell carcinoma revealed by bioinformatic analysis of gene expression data

Authors: B. Wang, T. Wang, X.L. Cao and Y. Li

In this study, bioinformatic analysis of gene expression data of head and neck squamous cell carcinoma (HNSCC) was performed to identify critical genes. Gene expression data of HNSCC were downloaded from the Cancer Genome Atlas (TCGA) and differentially expressed genes were determined through significance analysis of microarrays. Protein-protein interacti.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.10
DOI:
10.4238/2015.December.21.10
Animal Genetics   Research Article

Expression profiles of differentially expressed genes affecting fecundity in goat ovarian tissues

Authors: Y.H. Ling, Q. Quan, H. Xiang, L. Zhu, M.X. Chu, X.R. Zhang and C.Y. Han

Although RNA-Seq is an effective method for identifying and exploring novel functional genes in mammals, it has rarely been applied to study fertility-related genes in the goat. In this study, RNA-Seq was used to screen the estrus ovaries of uniparous and multiparous Anhui white goats (AWGs). In total, 15,890 genes were identified and 2201 of these were f.. Read More»

Genet. Mol. Res. 14(4):
2015.December.28.23
DOI:
10.4238/2015.December.28.23