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Acute Coronary Syndrome

Human Genetics   Research Article

Assessment of the rs4340 ACE gene polymorphism in acute coronary syndrome in a Western Mexican population

Authors: A. Valdez-Haro, Y. Valle, E. Valdes-Alvarado, F. Casillas-Mu�±oz, J.F. Mu�±oz-Valle, G.L. Reynoso-Villalpando, H.E. Flores-Salinas and J.R. Padilla-Guti�©rrez

Acute coronary syndrome (ACS) is considered one of the main causes of death worldwide. Contradictory findings concerning the impact of the angiotensin-converting enzyme (ACE) gene on cardiovascular diseases have been reported. Previous conclusions point out that the variability in results depends on ethnicity and genetic polym.. Read More»

Genet. Mol. Res. 16(3):
gmr16039779
DOI:
10.4238/gmr16039779
Medical Genetics   Research Article

High-sensitivity cardiac troponin T is a predictor of recurrent acute coronary syndrome in patients with acute myocardial infarction

Authors: S.-C. Sheng, X.-M. Lu, Y. Kang, Y.-P. Du and G.-X. Wang

High-sensitivity cardiac troponin T is a useful tool for diagnosing myocardial ischemia. However, its role in the prognosis of patients with acute myocardial infarction has not been studied. Here, the prognostic value of high-sensitivity cardiac troponin T for patients with acute myocardial infarction was investigated. The con.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.16.6
DOI:
http://dx.doi.org/10.4238/2014.May.16.6
Medical Genetics   Research Article

Correlation of serum high-sensitivity C-reactive protein and interleukin-6 in patients with acute coronary syndrome

Authors: X.H. Wang, S.Q. Liu, Y.L. Wang and Y. Jin

Serum high-sensitivity C-reactive protein (hs-CRP) is a sensitive indicator of inflammation, which is closely related with the progress of plaque formation. Interleukin-6 (IL-6) is one of the inflammatory markers of local coronary plaque and the peripheral blood cycle, promoting the occurrence of atherosclerosis development an.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.9.11
DOI:
http://dx.doi.org/10.4238/2014.June.9.11
Human Genetics   Research Article

ESR1 gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) may not be directly correlated with cardiovascular disease risk

Authors: N. Jiang, G. Yang and C.L. Peng

The aim of this meta-analysis was to evaluate the correlations between the estrogen receptor 1 (ESR1) gene polymorphisms PvuII (rs2234693T>C) and XbaI (rs9340799A>G) and the risk of cardiovascular disease (CVD). Case-control studies were screened and selected from a larger group of studies that were retrieved through a comprehensive search of scient.. Read More»

Genet. Mol. Res. 14(4):
2015.October.29.14
DOI:
10.4238/2015.October.29.14
Human Genetics   Research Article

Association of a transforming growth factor-�²1 polymorphism with acute coronary syndrome in a Chinese Han population

Authors: Y.N. Yang, B. Zhao, X.M. Li, X. Xie, F. Liu and B.D. Chen

Acute coronary syndrome (ACS) is a complex multifactorial and polygenic disorder that is thought to result from the interaction between an individual’s genetic makeup and various environmental factors. The aim of this study was to investigate the association of a transforming growth factor-β1 (TGF-β1) polymorph.. Read More»

Genet. Mol. Res. 13(3):
2014.April.3.2
DOI:
10.4238/2014.April.3.2
Human Genetics   Research Article

Changes of circulating CD4+CD25+CD127low regulatory T cells in patients with acute coronary syndrome and its significance

Authors: M. Liu, L.-J. Xu, J.-X. Wu

The aim of this study was to investigate the changes of circulating CD4+CD25+CD127low regulatory T cells (Treg) in patients with acute coronary syndrome (ACS) and its significance. The experiment was divided into three groups: ACS (48 patients), stable angina pectoris (SAP) (24 patients), and normal controls (24 subjects). The.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.4
DOI:
10.4238/2015.December.7.4
Medical Genetics   Research Article

Association study of plasma NT-proBNP levels and severity of acute coronary syndrome

Authors: T. Tuxunguli, A. Aierken, X. Xie, C.F. Dai, Y.N. Yang, X.M. Li and Y.T. Ma

The aim of this study was to investigate the N-terminal brain natriuretic peptide precursor (NT-proBNP) levels in the peripheral blood of patients with acute coronary syndrome (ACS) and to provide the basis for its application in the early diagnosis of ACS. A total of 440 patients admitted to the hospital for examination and t.. Read More»

Genet. Mol. Res. 13(3):
2014.July.29.2
DOI:
10.4238/2014.July.29.2