Analysis of ROP signaling in the leaf epidermis of mutant tomato with low-energy ion beam
Authors: Q.X. Liang,G.Q. Cao,S.P. Zhao,Q.C. Huang,F.Q. Ying and W. Chen
The importance of the ROP small GTPase signaling pathway in the regulation of cellular polarity growth in eukaryotes has been thoroughly studied. In this study, we examined the LeROP small GTPase (related to Arabidopsis thaliana genome LeROP GTPase in tomato) signaling of cell polarity growth in the mutant (M-1) tomato. Interestingly, we detected expansiv.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.10
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.10
Molecular characterization of a Han Chinese family with essential hypertension
Authors: J.F. Zhu, X. Zhang and L. Ling
Mutations in the mitochondrial genome have been found to be associated with essential hypertension. Here, we report the clinical and molecular characterization of a three-generation Han Chinese family with maternally inherited hypertension. Most strikingly, this pedigree exhibited a high penetrance of hypertension. Sequence an.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028084
- DOI:
- 10.4238/gmr.15028084
Adaptability of soybean cultivars in different crop years
Authors: I.O. Soares, P.M. Rezende, A.T. Bruzi, E.V. Zambiazzi, A.M. Zuffo, K.B. Silva and R. Gwinner
Soybean is one of the main sources of foreign exchange credits for Brazil in the agricultural sector. There is increasing interest in growing this leguminous crop, especially in the southern region of Minas Gerais, due to its importance as an alternative for crop rotation with maize. In this respect, the study of the adaptability of new cultivars to the r.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.8
- DOI:
- 10.4238/2015.August.7.8
tRNALeu intron (UAA) of Ficus carica L.: genetic diversity and evolutionary patterns
Authors: G. Baraket,A.B. Abdelkrim and A. Salhi-Hannachi
Cytoplasmic chloroplast DNA was explored to establish genetic relationships among Ficus carica cultivars and elucidate the molecular evolution of the species. The results suggest the occurrence of haplotype and nucleotide diversity. Conserved group I intron sequence motifs were detected and showed a common secondary structure, despite the presence of some.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.11
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.11
Association between a microRNA-214 binding site polymorphism in the methylenetetrahydrofolate reductase gene and esophageal squamous cell carcinoma
Authors: G.R. Shen, W.Z. Li, Y.C. Liu, X.P. Li and H.Y. Yuan
MicroRNAs (miRNAs) are key regulators of gene expression and play an important role in the development and progression of various diseases including esophageal squamous cell carcinoma (ESCC). In this study, we determined whether a polymorphism at the miR-214 binding site in the 3'-untranslated region (3'-UTR) of the methylenet.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028158
- DOI:
- 10.4238/gmr.15028158
Characteristic element of matrix attachment region mediates vector attachment and enhances nerve growth factor expression in Chinese hamster ovary cells
Authors: X.Y. Wang, J.H. Zhang, Q.L. Sun, Z.Y. Yao, B.G. Deng, W.Y. Guo,L. Wang, W.H. Dong, F. Wang, C.P. Zhao and T.Y. Wang
Preliminary studies have suggested that a characteristic element of the matrix attachment region (MAR) in human interferon-β mediates the adhesion of vectors to Chinese hamster ovary (CHO) cells. In this study, we investigated if vector adhesion increased nerve growth factor (NGF) expression in CHO cells. The MAR characteristic element sequence of hu.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.29
- DOI:
- 10.4238/2015.August.7.29
Factor analysis applied to genome prediction for high-dimensional phenotypes in pigs
Authors: F.R.F. Teixeira, M. Nascimento, A.C.C. Nascimento, F.F. e Silva, C.D. Cruz, C.F. Azevedo, D.M. Paix�£o, L.M.A. Barroso, L.L. Verardo, M.D.V. de Resende, S.E.F. Guimar�£es and P.S. Lopes
The aim of the present study was to propose and evaluate the use of factor analysis (FA) in obtaining latent variables (factors) that represent a set of pig traits simultaneously, for use in genome-wide selection (GWS) studies. We used crosses between outbred F2 populations of Brazilian Piau X commercial pigs. Data were obtain.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028231
- DOI:
- 10.4238/gmr.15028231
Association between rs155971 in the PCSK1 gene and the lipid profile of obese Thai children: a family-based study
Authors: S. Kulanuwat, J. Santiprabhob, B. Phonrat, C. Limwongse, A. Tungtrongchitr, N. Chongviriyaphan and R. Tungtrongchitr
Genetic variants of the POMC and PCSK1 genes cause severe obesity among patients in the early stages of childhood. This family-based study analyzed the links between single nucleotide polymorphisms (SNPs) in either the POMC or PCSK1 genes and obesity, as well as obesity-related traits among obese Thai children and their families. The variants rs1042571 an.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.23
- DOI:
- 10.4238/2015.August.7.23
Clinical observational study of conformal radiotherapy combined with topotecan chemotherapy in patients with platinum-resistant recurrent ovarian cancer
Authors: P. Wei,Z.H. Zhang,L. Li,X.L. Du,C.P. Shan and X.G. Sheng
This retrospective study aimed to observe the curative effect and adverse reactions of three-dimensional conformal radiotherapy combined with topotecan chemotherapy in patients with platinum-resistant recurrent epithelial ovarian carcinoma. The chemoradiotherapy group (N = 22) received 15 mv X-rays with 1.8 to 2.0 Gy/f/d radiation, 5 times per week. The t.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.12
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.12
Macrophage proinflammatory response to the titanium alloy equipment in dental implantation
Authors: X. Chen, H.S. Li, Y. Yin, Y. Feng and X.W. Tan
Titanium alloy and stainless steel (SS) had been widely used as dental implant materials because of their affinity with epithelial tissue and connective tissue, and good physical, chemical, biological, mechanical properties and processability. We compared the effects of titanium alloy and SS on macrophage cytokine expression as well as their biocompatibil.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.25
- DOI:
- 10.4238/2015.August.7.25