Detection and expression of bovine papillomavirus in blood of healthy and papillomatosis-affected cattle
Authors: M.A.R. Silva, B.M.F. De Albuquerque, N.E. Pontes, L.C.A. Coutinho, M.C.G. Leit�£o, M.C. Reis, R.S. Castro and A.C. Freitas
Papillomaviruses (PV) are double-stranded DNA viruses that can cause benignant and malignant tumors in amniotes. There are 13 types of bovine papillomavirus (BPV-1 to -13); they have been found in reproductive tissues and body fluids. Normally these viruses are detected in epithelial tissue. We looked for BPV in the blood of healthy cattle and cattle with.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.31
- DOI:
- 10.4238/2013.February.28.31
Molecular evolution of the melanocortin 1-receptor pigmentation gene in rodents
Authors: G.L. Gon�§alves, V.R. Paix�£o-C�´rtes and T.R.O. Freitas
Adaptive variation in the melanocortin 1-receptor gene (MC1R), a key locus in melanogenesis, has been identified in some species of rodents. However, in others, MC1R has no causative role in pigmentation phenotypes despite their coat color variation. In this study, we characterized the rates and patterns of MC1R nucleotide and amino acid sequence evolutio.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.24
- DOI:
- 10.4238/2013.February.28.24
All-trans retinoic acid prevents the development of type 1 diabetes by affecting the levels of interferon gamma and interleukin 4 in streptozotocin-induced murine diabetes model
Authors: Y. Wang, Y.J. Zhong, Y.Y. Wang, J. Xing and Z.M. Wang
The aim of this study was to explore the molecular mechanism by which all-trans retinoic acid (ATRA) prevents type 1 diabetes mellitus (T1DM). Fifty ICR mice were randomly assigned to three groups: prevention group [N = 20; mice received 10 mg/kg ATRA daily for 5 days and then 60 mg/kg streptozotocin (STZ) for 5 days]; diabeti.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017522
- DOI:
- 10.4238/gmr.15017522
Characterization of myostatin gene (MSTN) of Pekin duck and the association of its polymorphism with breast muscle traits
Authors: T.S. Xu, L.H. Gu, X.H. Zhang, B.G. Ye, X.L. Liu and S.S. Hou
Myostatin, encoded by the MSTN gene, is a negative regulator of muscle growth, and its expression level in muscle tissue is closely correlated with muscle growth and satellite cell proliferation. To identify the characteristics of the Pekin duck MSTN gene and the relationship between its polymorphism and breast muscle traits in Pekin duck, cDNA cloning an.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.18
- DOI:
- 10.4238/2013.February.28.18
Cytochemical characteristics of blood cells from Brazilian tortoises (Testudines: Testudinidae)
Authors: G.S. Martins, K.C.C. Alevi, M.T.V. Azeredo-Oliveira and C.R. Bonini-Domingos
The hematology of wild and captive animals is essential for obtaining details about species and represents a simple method of diagnosing disease and determining prognosis. Few studies have described the morphology of chelonian blood cells, which are more common in sea and freshwater turtle species. Thus, in order to further ou.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017549
- DOI:
- 10.4238/gmr.15017549
Interethnic variation of the MMP-9 microsatellite in Amerindian and Mexican Mestizo populations: considerations for genetic association studies
Authors: R. Camacho-Mejorado, G. Noris, C. Santana, J.J. MagaÃ?±a,A. Majluf-Cruz, J. Arellano-Galindo, A. De la PeÃ?±a, J. HernÃ?¡ndez-JuÃ?¡rez, E.S. CalderÃ?³n-Aranda, M.A. Meraz-RÃ?Âos and R. GÃ?³mez
We studied the interethnic variation of the MMP-9 microsatellite in the Mestizo and Amerindian populations using blood samples collected from 435 healthy unrelated individuals from the Central Valley of Mexico. DNA samples were genotyped using the -90 (CA)12-27 repeat near the MMP transcriptional start site using capillary ele.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.31.24
- DOI:
- 10.4238/2015.March.31.24
Loop-tail phenotype in heterozygous mice and neural tube defects in homozygous mice result from a nonsense mutation in the Vangl2 gene
Authors: B. Chen, H.H. Mao, L. Chen, F.L. Zhang, K. Li and Z.F. Xue
N-ethyl-N-nitrosourea (ENU) is a powerful point mutagen that can generate random mutations. It has been used to generate mouse mutations to produce phenotypic models of human disease. Neural tube defects (NTD) are common birth defects in which the brain and/or spinal cord can be exposed; however, the mechanisms of these defects are poorly understood. Cran.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.22.2
- DOI:
- 10.4238/2013.January.22.2
Prenatal diagnosis of a partial trisomy 13q (q14�qter): phenotype, cytogenetics and molecular characterization by spectral karyotyping and array comparative genomic hybridization
Authors: I.N. Machado, J.K. Heinrich, C. Campanhol, R.M. Rodrigues-Peres, F.M. Oliveira and R. Barini
Partial trisomy 13q is an uncommon chromosomal abnormality with variable phenotypic expression. We report prenatal diagnosis of partial trisomy 13q in a fetus with partial agenesis of the cerebellar vermis, partial agenesis of the corpus callosum, hydrops and polyhydramnios. G-banding karyotyping, spectral karyotyping and arra.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr716
- DOI:
- 10.4238/vol9-1gmr716
A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp
Authors: Y.B. Shen, J.B. Zhang, J.J. Fu, X.Y. Xu, J.L. Li R.Q. Wang and Y.F. Xuan
Aeromonas hydrophila, a widespread bacterium in the aquatic environment, causes hemorrhagic septicemia in fish. In the last decade, the disease has caused mass mortalities and tremendous economic loss in cultured fish. The complement component C7 is a terminal component of complement that interacts in a sequence of polymerizat.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15014526
- DOI:
- 10.4238/gmr.15014526
Polyandry in the red-headed river turtle Podocnemis erythrocephala (Testudines, Podocnemididae) in the Brazilian Amazon
Authors: C. Fantin, I.P. Farias, L.A.S. Monjel�³ and T. Hrbek
The genus Podocnemis comprises six living species, including P. erythrocephala (irapuca - red-headed river turtle). Data are available concerning the reproductive biology of the species of the genus Podocnemis, but little is known about their reproductive strategies. Considering the total lack of such data for P. erythrocephal.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr749
- DOI:
- 10.4238/vol9-1gmr749