Role of COL9A1 genetic polymorphisms in development of congenital talipes equinovarus in a Chinese population
Authors: X.L. Zhao, Y.J. Wang, Y.L. Wu, W.H. Han
Talipes equinovarus is a common congenital deformity. COL9A1 polymorphisms are associated with the development of articular cartilage-related diseases. In the current study, we evaluated the relationship between COL9A1 rs1135056, rs35470562, and rs592121 genetic polymorphisms and risk of congenital talipes equinovarus. Between.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048773
- DOI:
- 10.4238/gmr15048773
Limitations of cytochrome oxidase I for the barcoding of Neritidae (Mollusca: Gastropoda) as revealed by Bayesian analysis
Authors: S.Y. Chee
The mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) gene has been universally and successfully utilized as a barcoding gene, mainly because it can be amplified easily, applied across a wide range of taxa, and results can be obtained cheaply and quickly. However, in rare cases, the gene can fail to distinguish between species, particularly when expose.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.20
- DOI:
- 10.4238/2015.May.25.20
Detection of QTLs controlling fast kernel dehydration in maize (Zea mays L.)
Authors: Y.L. Qian, X.Q. Zhang, L.F. Wang, J. Chen, B.R. Chen, G.H. Lv, Z.C. Wu, J. Guo, J. Wang, Y.C. Qi, T.C. Li, W. Zhang, L. Ruan and X.L. Zuo
In order to understand the effect of grain moisture of inbred lines at the silking and physiological maturity stages on kerneldehydration rate, 59 maize inbred lines from six subgroups were selected. Grain moisture was measured and QTLs associated with kernel dehydration were mapped. A rapid dehydration evaluation and association analysis revealed eight i.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038151
- DOI:
- 10.4238/gmr.15038151
Isolation and characterization of polymorphic microsatellite markers in the endangered species Bretschneidera sinensis Hemsl.
Authors: M. Li, H.F. Chen, Z.F. Wang and S. Zhang
Bretschneidera sinensis is an endangered species that is mainly distributed in South China. As a tertiary relict and the single species in the Bretschneideraceae family, it has a high conservation value. To investigate the influence of human disturbance on its mating system, 63 new microsatellites were developed using restriction-site-associated DNA seque.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038234
- DOI:
- 10.4238/gmr.15038234
Polymorphisms in ADAMTS4 and ADAMTS5 are not linked to susceptibility to knee osteoarthritis in the Turkish population
Authors: U. Canbek, A. Imerci, M. Kara, U. Akgun, T.D. Canbek and N.H. Aydogan
Considering the functions of aggrecanase-1 (ADAMTS4) and -2 (ADAMTS5), which are thought to be the two major enzymes responsible for the destruction of aggrecans in arthritic diseases, we investigated whether important polymorphisms in the ADAMTS4 and ADAMTS5 genes affect osteoarthritis (OA) susceptibility. Our study took place in Mugla, Turkey. Ninety-fi.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038264
- DOI:
- 10.4238/gmr.15038264
Genetic variation of bovine leukemia virus (BLV) after replication in cell culture and experimental animals
Authors: M.F. Camargos, D.S. Raj�£o, R.C. Leite, D. Stancek, M.B. Heinemann and J.K.P. Reis
This article reports the selection of bovine leukemia virus (BLV) variants after continuous passage in cell lines or experimental animals. Two wild BLV strains isolated from 2 naturally infected Holstein dairy cows in Brazil (cow codes: 485 and 141) were used for the experimental infection of 1 sheep and FLK cells, and 1 rabbi.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.22.11
- DOI:
- http://dx.doi.org/10.4238/2014.January.22.11
Differential expression of genes during mastitis in Holstein-Zebu crossbreed dairy cows
Authors: I. Fonseca, G.R. Antunes, D.S. Paiva, C.C. Lange, S.E.F. Guimar�£es and M.F. Martins
Among the potential public health problems of animal production, infectious-contagious diseases stand out. Mastitis is among the main diseases affecting dairy cattle. One of the most promising options to reduce the problems caused by this disease, besides proper sanitary and management practices, is selective breeding of resis.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1096
- DOI:
- 10.4238/vol10-3gmr1096
Association of DNMT1 and DNMT3B polymorphisms with breast cancer risk in Han Chinese women from South China
Authors: M.-Y. Sun X.-X. Yang W.-W. Xu G.-Y. Yao H.-Z. Pan M. Li
Patterns of DNA methylation are established and maintained by a family of DNA methyltransferases (DNMTs). Aberrant promoter DNA methylation of tumor suppressor genes is found in breast cancer. Association studies between DNMT gene polymorphisms and breast cancer in various populations have reported inconsistent results. This study assessed the associations o.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.September.26.1
- DOI:
- 10.4238/2012.September.26.1
Development of a cyclic voltammetry method for the detection of Clostridium novyi in black disease
Authors: L.L. Liu, D.N. Jiang, G.M. Xiang, C. Liu, J.C. Yu and X.Y. Pu
Black disease is an acute disease of sheep and cattle. The pathogen is the obligate anaerobe, Clostridium novyi. Due to difficulties of anaerobic culturing in the country or disaster sites, a simple, rapid, and sensitive method is required. In this study, an electrochemical method, the cyclic voltammetry method, basing on loop.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.14.9
- DOI:
- http://dx.doi.org/10.4238/2014.January.14.9
RAPD and ISSR markers in the evaluation of genetic divergence among accessions of elephant grass
Authors: R.S.N de Lima, R.F. Daher, L.S.A. Gon�§alves, D.A. Rossi, A.T. do Amaral J�ºnior, M.G. Pereira and F.J.S. L�©do
Considering the expected genetic variability of elephant grass (Pennisetum purpureum), due to its cultivation in different continents, we characterized and estimated the genetic divergences between 46 accessions of elephant grass with different edaphoclimatic adaptations, using RAPD and ISSR markers. We evaluated, comparativel.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1107
- DOI:
- 10.4238/vol10-3gmr1107