Genetic relationships among turnip (Brassica rapa var. rapa) genotypes
Authors: E. Yildirim, N. Yildirim, S. Ercisli, G. Agar and H. Karlidag
Turnip (Brassica rapa var. rapa) is one of the main vegetables consumed by people living in Eastern Anatolia in Turkey. In this region, farmers obtain their own seeds for production, which results in considerable morphological variability. We examined the genetic variation and relationships among 11 turnip genotypes sampled fr.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr786
- DOI:
- 10.4238/vol9-2gmr786
Increased risk of breast cancer in individuals carrying the TNRC9 rs3803662 C>T polymorphism: a meta-analysis of case-control studies
Authors: Q. Wang, N.Y. Wang, X.M. Cao, X. Sun, D. Shen, M. Yuan and J.F. Chen
Currently, the relationship between the trinucleotide repeat containing 9 (TNRC9) rs3803662 C>T polymorphism and risk of breast cancer (BC) is uncertain. Here, we attempted to obtain a more accurate assessment of this association by conducting a meta-analysis of all eligible case-control investigations, comprising 44,820 cases and 58,316 controls. A co.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038218
- DOI:
- 10.4238/gmr.15038218
Mutations in the FGFR2 gene in Mexican patients with Apert syndrome
Authors: A. Ibarra-Arce, G. Ortiz de ZÃ?¡rate-AlarcÃ?³n, L.G. Flores-PeÃ?±a,F. MartÃ?Ânez-HernÃ?¡ndez, M. Romero-Valdovinos and A. Olivo-DÃ?Âaz
Apert syndrome (AS) is a frequent acrocephalosyndactyly, with autosomal dominant inheritance. AS has been associated with mutations in fibroblast growth factor receptor 2 (FGFR2), and approximately 99% of cases show 2 of the frequent mutations located in exon IIIa (Ser252Trp or Pro253Arg). The purpose of the present study was to describe the mutations in .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.19
- DOI:
- 10.4238/2015.March.27.19
Genomic prediction for additive and dominance effects of censored traits in pigs
Authors: V.S. Santos, S. Martins Filho, M.D.V. Resende, C.F. Azevedo, P.S. Lopes, S.E.F. Guimar�£es and F.F. Silva
Age at the time of slaughter is a commonly used trait in animal breeding programs. Since studying this trait involves incomplete observations (censoring), analysis can be performed using survival models or modified linear models, for example, by sampling censored data from truncated normal distributions. For genomic selection,.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048764
- DOI:
- 10.4238/gmr15048764
Analysis of genetic diversity of Tunisian pistachio (Pistacia vera L.) using sequence-related amplified polymorphism (SRAP) markers
Authors: K. Guenni, M. Aouadi, K. Chatti and A. Salhi-Hannachi
Sequence-related amplified polymorphism (SRAP) markers preferentially amplify open reading frames and were used to study the genetic diversity of Tunisian pistachio. In the present study, 43 Pistacia vera accessions were screened using seven SRAP primer pairs. A total of 78 markers was revealed (95.12%) with an average polymor.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048760
- DOI:
- 10.4238/gmr15048760
Association between -44G/A and +71A/G polymorphisms in the connexin 40 gene and atrial fibrillation in Uyghur and Han populations in Xinjiang, China
Authors: J. Hailati, Y.C. Yang, L. Zhang, P.Y. He, M. Baikeyi, W. Muhuyati and Z.Q. Liu
We aimed to elucidate the association between connexin 40 (Cx40) genetic polymorphisms and atrial fibrillation (AF) in a Chinese population in Xinjiang comprising Uyghur and Han individuals. We enrolled 275 Uyghur and 305 age- and gender-matched Han subjects, and used polymerase chain reaction to detect single nucleotide polym.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048628
- DOI:
- 10.4238/gmr15048628
Preliminary study of the effects of �²-elemene on MCF-7/ADM breast cancer stem cells
Authors: Y. Dong, L. Li, L. Wang, T. Zhou, J.W. Liu and Y.J. Gao
We examined expression differences in breast cancer stem cells (BCSCs) of the doxorubicin-resistant breast cancer cell line MCF-7/ADM and doxorubicin-sensitive cell line MCF-7/S. The effects of Chinese medicine β-elemene on BCSCs and resistance protein expression were determined. The serum-free cell culture method was used for cell culture, and morph.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.20
- DOI:
- 10.4238/2015.March.27.20
Development of EST-SSR markers in the relict tree Davidia involucrata (Davidiaceae) using transcriptome sequencing
Authors: Z.C. Long, A.W. Gichira, J.M. Chen, Q.F. Wang and K. Liao
Davidia involucrata, reputed to be a “living fossil” in the plant kingdom, is a relict tree endemic to China. Extant natural populations are diminishing due to anthropogenic disturbance. In order to understand its ability to survive in a range of climatic conditions and to design conservation strategies for this en.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048539
- DOI:
- 10.4238/gmr15048539
A multi-center study on the prophylactic application of antibiotics in aseptic operations
Authors: Y. Ma, L. Bao, H. Wang and S. Shi
To understand the application of antibacterial agents in aseptic operations and to provide evidence for their rational use and management, the antibiotic use statuses of six types of aseptic operations (306 cases from 4 tertiary hospitals) were retrospectively analyzed. Of 312 patients, 306 (65.08%) were treated with antibacterial agents in the perioperat.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.21
- DOI:
- 10.4238/2015.March.27.21
Role of IL-8 rs4073 and rs2227306 polymorphisms in the development of primary gouty arthritis in a Chinese population
Authors: Y.X. Cui, H. Zhao and H.Q. Guo
In this study, we investigated the role of two single nucleotide polymorphisms in the promoter region of the interleukin-8 gene (IL-8; rs4073 and rs2227306) in the susceptibility to primary gouty arthritis in a Chinese population. Three hundred and twelve patients with primary gouty arthritis and 340 healthy controls were recr.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048511
- DOI:
- 10.4238/gmr15048511