Effects of glial cell line-derived neurotrophic factor and leukemia-inhibitory factor on the behavior of two calf testis germline stem cell colony types
Authors: P. Zheng, H. Huang, Y.G. Tian, Y. Zeng, E.O. Adegoke, X. Wang and G.X. Zhang
Germline stem cells are the only such capable of transmitting genetic information in vivo. The isolation and culture of these cells in vitro provide a unique model to understand sperm differentiation and hence, spermatogenesis and male fertility. In this study, we isolated, purified, and cultured germline stem cells from the t.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048856
- DOI:
- 10.4238/gmr15048856
Insights about the genetic diversity and population structure of an offshore group of common bottlenose dolphins (Tursiops truncatus) in the Mid-Atlantic
Authors: C.S. Castilho, F. Pedone-Valdez, F. Bertuol, P. Fruet, R.C. Genoves, J.C. Di Tullio, G. Caon, L.S. Hoffmann and T.R.O. Freitas
Although the genus Tursiops has a worldwide distribution and is globally well-studied, some dolphin populations continue to face high risks of decline. Hence, it is necessary to assess the genetic diversity and structure of this genus to properly assess its conservation status and to implement appropriate management actions. In Brazil, genetic studies on .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.15.2
- DOI:
- http://dx.doi.org/10.4238/2015.April.15.2
Reduced cortisol in the absence of bacterial infection in patients with hepatitis B virus cirrhosis
Authors: J. Zhang, H.-W. Yu, J. Li, Y.-K. Zhu, K.-F. Wang, L. Jia and Q.-H. Meng
In liver cirrhosis with bacterial infection, hepatoadrenal syndrome has been described recently as a progressive impairment in the adrenocortical reserve, with deficient production or action of glucocorticoids resulting in adrenal insufficiency. The aim of this study was to explore the characteristics of cortisol in hepatitis B virus (HBV) cirrhosis patie.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.3
- DOI:
- 10.4238/2015.July.17.3
Impact of citrate pretreatment on ventricular arrhythmia and myocardial capase-3 expression in ischemia/reperfusion injury
Authors: Q. Lu, Z.G. Li1,, N. Zhou, Z.G. Gong, J.Q. Jiang, Z.N. Chen, Q.J. Jiang, Y. Peng and S.F. Ding
Ischemia/reperfusion (I/R) injury often triggers ventricular arrhythmia. Citrate binds calcium ions, forming a soluble calcium citrate complex that may reduce I/R injury by affecting calcium ion concentration. We tested the effects of citrate pretreatment on ventricular heart rate and related factors in a rat I/R model. Fifty .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048848
- DOI:
- 10.4238/gmr15048848
Relationship between glutathione S-transferase P1 polymorphisms and chronic obstructive pulmonary disease in a Tunisian population
Authors: R. Lakhdar, S. Denden, J. Knani, N. Leban, H. Daimi, M. Hassine, G. Lefranc, J. Ben Chibani and A. Haj Khelil
Chronic obstructive pulmonary disease (COPD) is a multifactorial disease with possible genetic predisposition and involvement of various environmental factors. Several candidate genes have been reported as potentially associated with this lung disease. The glutathione S-transferase P1 gene (GSTP1) was proposed to be involved i.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr770
- DOI:
- 10.4238/vol9-2gmr770
Association between IL6 polymorphism and risk of cerebral infarction
Authors: Y.H. Han
We conducted a case-control study to investigate the influence of IL6 -174G/C (rs1800795) and -572C/G (rs1800796) genetic variants on the development of cerebral thrombosis in a Chinese population. This study included 305 cerebral infarction patients and 326 control subjects enrolled between May 2012 and May 2014. The genotyping of IL6 -174G/C (rs1800795).. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Characterization of microsatellite markers for the Restinga Antwren, Formicivora littoralis (Thamnophilidae), an endangered bird endemic to Brazil
Authors: F.G. Chaves, M.B. Vecchi, M.S. Webster and M.A.S. Alves
Molecular markers are important tools in determining parentage, gene flow, and the genetic structure of species. In the case of rare, endemic, and/or threatened species, these markers can be used to understand key ecological questions and support conservation actions. We developed seven microsatellite markers for the only bird endemic to the Restinga ecos.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.6
- DOI:
- 10.4238/2015.July.17.6
Genome-wide expression analysis of a rice mutant line under salt stress
Authors: K.J. Lee, S.-J. Kwon, J.E. Hwang, S.M. Han, I. Jung, J.-B. Kim, H.-I. Choi, J. Ryu and S.-Y. Kang
Salinity is a major environmental stress to plants. In this study, the ability of plants to tolerate salt was investigated by studying growth, physiological characteristics, and expression levels of genes related to the salt-stress response in the salt-tolerant rice mutant (Till-II-877), which was derived from γ-ray irra.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048833
- DOI:
- 10.4238/gmr15048833
Isolation, partial characterization, and cloning of an extracellular chitinase from the entomopathogenic fungus Verticillium lecanii
Authors: G. Yu, L.Q. Xie, J.T. Li, X.H. Sun, H. Zhang, Q. Du, Q.Y. Li,S.H. Zhang and H.Y. Pan
The entomopathogenic fungus Verticillium lecanii is a well-known biocontrol agent of fungal phytopathogens, as well as insect pests. A 42-kDa chitinase belonging to family 18 of the glycosyl hydrolases was isolated and partially characterized. Chitinase was purified using successive column chromatography on phenyl-sepharose, DEAE-sepharose, and CM-sepharo.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.13
- DOI:
- 10.4238/2015.March.27.13
Molecular marker-assisted selection of the ae alleles in maize
Authors: F. Chen, S.W. Zhu, Y. Xiang, H.Y. Jiang and B.J. Cheng
The ae (amylose extender) recessive mutant alleles in maize are an important genetic resource for the development of high-amylose cultivars. On the basis of ae allele sequences (from the National Center for Biotechnology Information), the ae mutant alleles were cloned from high-amylose maize and the allelic Ae gene from common.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr799
- DOI:
- 10.4238/vol9-2gmr799