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Plant Genetics   Research Article

Introgression of cotton leaf curl virus-resistant genes from Asiatic cotton (Gossypium arboreum) into upland cotton (G. hirsutum)

Authors: S. Ahmad, K. Mahmood, M. Hanif, W. Nazeer, W. Malik, A. Qayyum, K. Hanif, A. Mahmood and N. Islam

Cotton is under the constant threat of leaf curl virus, which is a major constraint for successful production of cotton in the Pakistan. A total of 3338 cotton genotypes belonging to different research stations were screened, but none were found to be resistant against the Burewala strain of cotton leaf curl virus (CLCuV). We .. Read More»

Genet. Mol. Res. 10(4):
2011.October.7.2
DOI:
10.4238/2011.October.7.2
Plant Genetics   Research Article

Relationship between progeny growth performance and molecular marker-based genetic distances in Eucommia ulmoides parental genotypes

Authors: Y. Li, Y.C. Wei, Z.Q. Li, S.H. Wang and L. Chang

Progeny performances, variations and combining abilities for growth traits were evaluated in a factorial mating design of Eucommia ulmoides. Three marker systems, sequence-related amplified polymorphism, amplified fragment length polymorphism, and inter-simple sequence repeat, were u.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.3
DOI:
10.4238/2014.July.2.3
Human Genetics   Research Article

Analysis of CD38 and ZAP70 mRNA expression among cytogenetic subgroups of Iranian chronic-lymphocytic-leukemia patients

Authors: H. Teimori, M.T. Akbari, M. Hamid, M. Forouzandeh and E. Bibordi

Chromosomal abnormalities and ZAP70 expression profile are two major independent prognostic markers in B-cell chronic lymphocytic leukemia. We investigated a possible correlation between these two markers. ZAP70 expression using real-time RT-PCR was examined in 20 B-cell chronic lymphocytic leukemia patients with del13q14, 13 .. Read More»

Genet. Mol. Res. 10(4):
2011.October.7.3
DOI:
10.4238/2011.October.7.3
Animal Genetics   Research Article

Lactoferrin mRNA expression in mouse mammary glands during pregnancy and lactation

Authors: H.P. Li, X.L. Jiao, X.J. Wang, F.T. Liu, H.S. Zhu, Y.Y. Wang and G.Y. Yang

Lactoferrin (Lf) is an iron-binding glycoprotein that is produced by mucosal epithelial cells in mammals. Lf has non-immune natural defense functions and biological functions in addition to and distinct from its role in regulating inflammatory responses. Lf also improved some physiological a.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.4
DOI:
10.4238/2014.July.2.4
Human Genetics   Research Article

Genetic diversity of HLA-DRB1 alleles in the Tujia population of Wufeng, Hubei Province, China

Authors: X.P. Qiu, L. Zhang, F.Y. Zeng, Y. Wen, C. Li, L.X. Qiu, D.X. Cheng and X.X. Wu

We established a genetic database by investigating human leukocyte antigen (HLA)-DRB1 allelic frequencies in a disease-association study in the Tujia population in Wufang, Hubei, China. The allele frequencies of the HLA-DRB1 locus in 262 healthy, unrelated Tujia individuals living in the Wufeng region of the Hubei Province wer.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.5
DOI:
10.4238/2014.July.2.5
Human Genetics   Research Article

Molecular characterization of Anthurium genotypes by using DNA fingerprinting and SPAR markers

Authors: J.D. Souza Neto, T.C.B. Soares, L.B. Motta, P.D.S. Cabral and J.A. Silva

We characterized single primer amplification reaction (SPAR) molecular markers from 20 genotypes of Anthurium andraeanum Lind., including 3 from commercial varieties and 17 from 2 communities in the State of Espírito Santo, Brazil. Twenty-four SPAR, consisting of 7 random amplified polymorphic DNA and 17 inter-.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.6
DOI:
10.4238/2014.July.2.6
Animal Genetics   Research Article

New roles of filopodia and podosomes in the differentiation and fusion process of osteoclasts

Authors: R.L. Song, X.Z. Liu, J.Q. Zhu, J.M. Zhang, Q. Gao, H.Y. Zhao, A.Z. Sheng, Y. Yuan, J.H. Gu, H. Zou, Q.C. Wang and Z.P. Liu

The cytoskeleton mediates various cellular processes such as differentiation and fusion, including in the filopodia and podosomes. However, apart from cell migration and formation of the sealing zone, little is known regarding the changes and related regulatory mechanisms of the cytoskeleton and additional roles of the filopod.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.7
DOI:
10.4238/2014.July.2.7
Medical Genetics   Research Article

Prevalence of cystathionine beta synthase gene mutation 852Ins68 as a possible risk for neural tube defects in eastern India

Authors: A.K. Saxena, J. Gupta, S. Pandey, A.N. Gangopadhaya and L.K. Pandey

Cystathionine beta synthase gene (CβS) catalyzes the condensation of homocysteine with serine, forming cystathionine by the transsulfuration pathway. Disruption of CβS enzyme activity due to defective folic acid metabolism increases the risk factor for neural tube defects. We evaluated the CβS gene mutation in 2.. Read More»

Genet. Mol. Res. 10(4):
2011.October.7.4
DOI:
10.4238/2011.October.7.4
Animal Genetics   Research Article

Identification of complex vertebral malformation carriers in Holstein cattle in south China

Authors: C. Wang, Q. Tong, X.Z. Hu, L.G. Yang, X.Q. Zhong, Y. Yu, J.J. Wu, W.J. Liu, X. Li, G.H. Hua, H.Q. Zhao and S.J. Zhang

Complex vertebral malformation (CVM) is a recently described monogenic autosomal recessive hereditary defect of Holstein dairy cattle that causes premature birth, aborted fetuses and stillborn calves. Guanine is substituted by thymine (G>T) in the solute carrier family 35 member A3 gene (SLC35A3). A valine is changed to a p.. Read More»

Genet. Mol. Res. 10(4):
2011.October.13.1
DOI:
10.4238/2011.October.13.1
Medical Genetics   Research Article

Meta-analysis of the relationship between p21 Ser31Arg polymorphism and lung cancer susceptibility

Authors: G. Lin, F. Fang, X.-J. Yu and L. Yu

The cyclin-dependent kinase inhibitor 1A (also known as p21) is thought to be involved in tumor development by mediating cell cycle arrest through the inhibition of cyclin/CDK activity. To explore the relationship of Ser31Arg polymorphism in the p21 gene with the risk of developing lung cancer, we performed an overall and stra.. Read More»

Genet. Mol. Res. 10(4):
2011.October.13.2
DOI:
10.4238/2011.October.13.2