Novel and highly informative Capsicum SSR markers and their cross-species transferability
Authors: G.S.C. Buso, A.M.M. Reis, Z.P.S. Amaral and M.E. Ferreira
This study was undertaken primarily to develop new simple sequence repeat (SSR) markers for Capsicum. As part of this project aimed at broadening the use of molecular tools in Capsicum breeding, two genomic libraries enriched for AG/TC repeat sequences were constructed for Capsicum annuum. A total of 475 DNA clones were sequenced from both libraries and 1.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038689
- DOI:
- 10.4238/gmr.15038689
Prevalence of �²-lactamase classes A, C, and D among clinical isolates of Pseudomonas aeruginosa from a tertiary-level hospital in Bangkok, Thailand
Authors: C. Katvoravutthichai, K. Boonbumrung and R. Tiyawisutsri
Pseudomonas aeruginosa is one of the most important causes of nosocomial infection and it has increasing resistance to many antimicrobial agents. β-lactamase production is the most frequent mechanism for β-lactam resistance in P. aeruginosa. We evaluated the prevalence of β-lactamase genes in P. aeruginosa for classes A, C, and D by polymer.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038706
- DOI:
- 10.4238/gmr.15038706
Development and characterization of single nucleotide polymorphism markers in Camellia sinensis (Theaceae)
Authors: C.C. Zhang, L.Y. Wang, K. Wei and H. Cheng
Tea is the second most popular non-alcoholic beverage in the world. In recent years, several molecular markers have been used in genetic studies of the tea plant. Yet, only a few single nucleotide polymorphisms (SNPs) have been reported. Here, we identified 818 putative SNPs from expressed sequence tag (EST) databases for the .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.10
- DOI:
- 10.4238/2014.April.14.10
Clinical significance of combined liver function and high-sensitivity C-reactive protein measurement in children with hand-foot-mouth disease
Authors: F.X. Han, J.H. Gao and J.H. Gai
Hand-foot-mouth disease (HFMD) is a common pediatric disease responsible for the development of rashes or herpes on the hand, foot, and mouth. Severe complications of HFMD include myocarditis, pulmonary edema, aseptic meningoencephalitis, and even death. Therefore, early diagnosis of HFMD is of particular importance. In this study, we determined the clini.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038744
- DOI:
- 10.4238/gmr.15038744
Analysis of genetic diversity and trait correlations among Korean landrace rice (Oryza sativa L.)
Authors: F.P. Li, Y.S. Lee, S.W. Kwon, G. Li and Y.J. Park
This study analyzed 394 Korean rice landrace accessions, including 93 waxy varieties, for polymorphisms using 29 simple sequence repeat (SSR) markers. In total, 381 alleles served as raw data for estimating the genetic diversity (GD) and population structure. The number of alleles per locus ranged from 3 to 44 (average = 13.14.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.12
- DOI:
- 10.4238/2014.April.14.12
Marsdenia tenacissima extract sensitizes MG63 cells to doxorubicin-induced apoptosis
Authors: T. Huang, W.H. Gong, C.P. Zou, X.C. Li, G.J. Jiang, X.H. Liand H. Qian
Marsdenia tenacissima extract (MTE) is a new plate-derived biotechnology product that is frequently used, but occasionally reported, in the field of chemotherapy. In this study, we assessed the antitumor activity and related mechanisms of MTE by various biotechnological methods. The survival rates of MG63 osteosarcoma cells tr.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.3
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.3
Clinical value of detection of immune index and inflammatory reaction changes in patients with autoimmune disease
Authors: X.J. Zhang, H.Y. Zhou and Y. Li
Previous studies have shown a close correlation between the generation of B cell autoantibodies and imbalances in T lymphocyte subpopulations and the occurrence of disease. In this study, we have analyzed the effects of abnormal expression of CD4+CD25+-regulatory T cells, T lymphocyte subpopulations, immunoglobulins, complement factors, inflammatory facto.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038745
- DOI:
- 10.4238/gmr.15038745
Effects of stingless bee and honey bee propolis on four species of bacteria
Authors: A.P. Farnesi, R. Aquino-Ferreira, D. De Jong, J.K. Bastosand A.E.E. Soares
We examined the antibacterial activities of several types of propolis, including Africanized honey bee green propolis and propolis produced by meliponini bees. The antibacterial activity of green propolis against Micrococcus luteus and Staphylococcus aureus was superior to that of Melipona quadrifasciata and Scaptotrigona sp p.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2kerr023
- DOI:
- 10.4238/vol8-2kerr023
Establishment of cytochrome P450 3A4 and glutathione S-transferase A1-transfected human hepatoma cell line and functional analysis
Authors: B.X. Chang, S.L. You, H.L. Liu, P.Y. Mao and S.J. Xin
This study aimed to enhance the drug metabolism function of the human hepatoma cell line C3A and to explore the related significance for patients with severe liver disease. The important liver phase I and phase II drug metabolism enzymes, cytochrome P450 3A4 (CYP 3A4) and glutathione S-transferase A1 (GST A1), were constructed.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.11
- DOI:
- 10.4238/2014.April.14.11
Direct sequencing of mutations in the copper-transporting P-type adenosine triphosphate (ATP7B) gene for diagnosis and pathogenesis of Wilson�s disease
Authors: D.F. Zhang and J.F. Teng
Copper-transporting P-type adenosine triphosphatase (ATP7B) has been identified as the pathogenic gene in hepatolenticular degeneration, or Wilson’s disease (WD). The aim of this study was to explore the correlation between genetic mutations and the clinical profile of WD, and to discuss the value of mutation examination in its diagnosis for providi.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038746
- DOI:
- 10.4238/gmr.15038746