Computational identification of miRNAs and their targets in Phaseolus vulgaris
Authors: J. Han, H. Xie, M.L. Kong, Q.P. Sun, R.Z. Li and J.B. Pan
MicroRNAs (miRNAs) are a class of non-coding small RNAs that negatively regulate gene expression at the post-transcriptional level. Although thousands of miRNAs have been identified in plants, limited information is available about miRNAs in Phaseolus vulgaris, despite it being an important food legume worldwide. The high cons.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.17.16
- DOI:
- 10.4238/2014.January.17.16
Matrix metalloproteinase-3 gene polymorphism and its mRNA expression in rheumatoid arthritis
Authors: M.J. Ma, H.C. Liu, X.Q. Qu, J.L. Wang
Matrix metalloproteinase-3 (MMP-3) can mediate the occurrence and development of rheumatoid arthritis (RA). The MMP3 promoter gene exhibits polymorphism with 5A/6A alleles. We investigated the correlation between the expression of MMP3 gene polymorphism and RA to provide an objective basis for prognosis evaluation. We enrolled.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.17
- DOI:
- 10.4238/2015.December.1.17
Effects of polymorphisms in the XRCC1, XRCC3, and XPG genes on clinical outcomes of platinum-based chemotherapy for treatment of non-small cell lung cancer
Authors: Z.Y. Jin, X.T. Zhao, L.N. Zhang, Y. Wang, W.T. Yue and S.F. Xu
This study aimed to investigate the effects of single-nucleotide polymorphisms (SNPs) XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPG His104Asp, and XPG His46His in genes involved in the DNA-repair pathway on the outcomes of platinum-based chemothera.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.31.13
- DOI:
- 10.4238/2014.March.31.13
Pollen foraging in colonies of Melipona bicolor (Apidae, Meliponini): effects of season, colony size and queen number
Authors: S.D. Hil�¡rio and V.L. Imperatriz-Fonseca
We evaluated the ratio between the number of pollen foragers and the total number of bees entering colonies of Melipona bicolor, a facultative polygynous species of stingless bees. The variables considered in our analysis were: seasonality, colony size and the number of physogastric queens in each colony. The pollen forager ra.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2kerr029
- DOI:
- 10.4238/vol8-2kerr029
Polymorphisms associated with egg number at 300 days of age in chickens
Authors: H.P. Xu, H. Zeng, D.X. Zhang, X.L. Jia, C.L. Luo, M.X. Fang, Q.H. Nie and X.Q. Zhang
We looked for variations that could be associated with chicken egg number at 300 days of age (EN300) in seven genes of the hypothalamic-pituitary-gonadal axis, including gonadotrophin-releasing hormone-I (GnRH-I), GnRH receptor (GnRHR), neuropeptide Y (NPY), dopamine D2 receptor (DRD2), vasoactive intestinal polypeptide (VIP),.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.3.5
- DOI:
- 10.4238/2011.October.3.5
Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure
Authors: X.S. Gu, Z.B. Wang, Z. Ye, J.P. Lei, L. Li, D.F. Su and X. Zheng
Reduced AMP-activated protein kinase (AMPK) expression has been shown to play a significant role in the cardiac dysfunction in heart failure. This study was designed to examine the effect of resveratrol, a potent activator of silent information regulator (SIRT1), on cardiac function and AMPK expression in heart failure. Adult .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.17.17
- DOI:
- http://dx.doi.org/10.4238/2014.January.17.17
Genomic survey and gene expression analysis of the VDAC gene family in rice
Authors: X. Xu*, Y.P. Tan, G. Cheng, X.Q. Liu, C.J. Xia, F.Y. Luo,C.T. Wang
The voltage-dependent anion channel (VDAC), also known as a mitochondrial porin, plays an important role in the regulation of metabolic and energetic functions of mitochondria, as well as in mitochondria-mediated apoptosis. Cytoplasmic male sterility (CMS) is of major economic importance for commercial hybrid production and a .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.20
- DOI:
- 10.4238/2015.December.1.20
Association of a transforming growth factor-�²1 polymorphism with acute coronary syndrome in a Chinese Han population
Authors: Y.N. Yang, B. Zhao, X.M. Li, X. Xie, F. Liu and B.D. Chen
Acute coronary syndrome (ACS) is a complex multifactorial and polygenic disorder that is thought to result from the interaction between an individual’s genetic makeup and various environmental factors. The aim of this study was to investigate the association of a transforming growth factor-β1 (TGF-β1) polymorph.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.3.2
- DOI:
- 10.4238/2014.April.3.2
Diversity of arthropod community in transgenic poplar-cotton ecosystems
Authors: D.J. Zhang,Z.Y. Lu,J.X. Liu,C.L. Li, M.S. Yang
Poplar-cotton agro-ecosystems are the main agricultural planting modes of plain cotton fields in China. Here, we performed a systematic survey of the diversity and population of arthropod communities in four different combination of poplar-cotton eco-systems, including I) non-transgenic poplar and non-transgenic cotton fields;.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.23
- DOI:
- 10.4238/2015.December.1.23
Identification and expression analysis of the Broad-Complex core protein isoform 6 (BR-C Z6) gene in the giant tiger shrimp Penaeus monodon (Penaeidae: Decapoda)
Authors: A. Buaklin, S. Klinbunga and P. Mensveta
Broad-Complex (BR-C) is an early ecdysone-responsive gene encoding a family of zinc-finger transcription factors that function during metamorphosis in insects. We identified two full-length cDNAs of BR-C Z6 in the giant tiger shrimp (Penaeus monodon). They were 2422 and 2060 bp in length, containing open reading frames of 1440.. Read More»
- Genet. Mol. Res. 10(4):