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Roles of GILZ in protein metabolism of L6 muscle cells exposed to serum from septic rats

Author(s): J. Xiong1,2*, L. Xu1,2*, W.M. Qu1,2, Z.L. Li3, Z.H. Shang1,2, Y.H. Li1, S.H. Yang1,2 and Z.H. Yang1,2

Sepsis is a complex inflammatory response to infection, associating with dramatic metabolic disorders. Although the mechanisms of immune response during sepsis have been largely clarified, current studies rarely pay attention to the disordered protein metabolism in sepsis. In this study, L6 rat skeletal muscle cells treated with serum from septic rats were used as an in vitro model for sepsis-like condition in skeletal muscle.