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Preoperative chemotherapy with a trastuzumab-containing regimen for a patient with gastric cancer and hepatic metastases

Author(s): Z.-Y. Li, F. Shan, L.-H. Zhang, Z.-D. Bu, A.-W. Wu, X.-J. Wu, X.-L. Zong, S.-X. Li, X. Ji and J.-F. Ji

Gastric cancer is the fourth most common cancer worldwide and the leading cause of tumor-related death in China. Gastric cancer is a heterogeneous disease and therefore requires different treatments based on the subtype. We describe a patient who had gastric cancer with liver metastases. Biopsy and tumor analysis using the HercepTest revealed a human epidermal growth factor receptor 2 (HER2)-positive adenocarcinoma as confirmed by fluorescence in situ hybridization.