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Mapping quantitative trait loci for the lysozyme level and immunoglobulin G blocking percentage of classical swine fever virus

Author(s): X. Lu, Y.F. Gong, J.F. Liu, Y. Liu and Q. Zhang

Increased disease resistance through improved general immune capacity would be beneficial for the welfare and productivity of farm animals. Classical swine fever (CSF) is a contagious disease in farm animals. The immunoglobulin G (IgG) blocking percentage of CSF virus (CSFV) in serum is an essential diagnostic parameter in veterinary practice. In addition, lysozymes are a part of the innate immune system. To identify quantitative trait loci (QTL) for IgG blocking percentage of CSFV and lysozyme concentration, IgG blocking percentage and lysozyme concentration in serum were measured in a composite pig population before and after challenge with modified live CSF vaccine.