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Decreased retinol-binding protein 4 in the sera of patients with end-stage renal disease after kidney transplantation

Author(s): W.X. Zhang1, W. Zhou1, Z.M. Zhang1, Z.Q. Zhang1, J.F. He2 and B.Y. Shi3

Retinol-binding protein 4 (RBP4) is a novel adipokine that has been associated with insulin resistance and type 2 diabetes. Patients with end-stage renal disease (ESRD) have very high serum RBP4 levels. However, whether successful kidney transplantation alleviates these elevated serum RBP4 levels is unclear. The serum RBP4 levels of 24 ESRD patients were determined before transplantation and at 1 day, 1 week, and 1 month after kidney transplantation.