Abstract
Association between p53 codon 72 polymorphisms and clinical outcome of nasopharyngeal carcinoma
Author(s): M.L. Li, Y. Dong, Y.Z. Hao, N. Xu, F.L. Ning, S.S. Chen and J.M. YuWe conducted a cohort study to investigate whether polymorphisms in p53 at codon 72 are associated with tumor response and survival time of advanced nasopharyngeal carcinoma (NPC) patients treated with radiotherapy. The study population included 127 subjects with NPC who were enrolled at Binzhou Medical University between September 2008 and December 2009. Cox proportional hazard regression was used to assess the association between polymorphisms in the p53 gene and progression-free survival (PFS) and overall survival (OS) of NPC patients.
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