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Human Genetics   Review Article
Integrative omics of ovarian cancer

Authors: Yanisa Rattanapan and Takol Chareonsirisuthigul

Omics such as genomics, transcriptomics, proteomics, and metabolomics are gathering the study of entire characterization and molecular biology processes of organisms. The advancement in studying omics has become useful and widely applied to many human diseases. For ovarian cancer, pathogenic mechanisms at molecular levels resulting in the development of c.. Read More»

Genet. Mol. Res. 18(4):

Medical Genetics   Research Article
The clinical significance of miR-7-5p downregulation in gastric dysplasia and gastric cancer tissue

Authors: Sara Omrani, Ali Zare, Shahriar Tarighi, Hamid Ghaedi, Mir Davood Omrani

miRNAs have been involved in the pathogenesis of several cancers such as gastric cancer (GC.). In the following study we analyzed the expression of miR-7 in gastric cancer samples compared non-tumor tissues and gastric dysplasia (GD) samples with patients’ clinico-pathological data and its potential as diagnostic biomarker. We first analyzed its exp.. Read More»

Genet. Mol. Res. 18(4):

Medical Genetics   Research Article
Relationship between melanoma-associated antigen 1 (MAGE-A1) gene polymorphisms and colorectal cancer development

Authors: Mikhlid Almutairi and Abdelhabib Semlali

In the Saudi population, colorectal cancer (CRC) is the first and third most common malignancy among males and females, respectively. The CRC risk is associated with the expression of certain genes, which can be used for prognoses and for finding screening-related biomarkers. One such gene is melanoma-associated antigen 1 (MAGE-A1); however, little is kno.. Read More»

Genet. Mol. Res. 18(4):